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Cl− Influx into Rat Cortical Lens Fiber Cells Is Mediated by a Cl− Conductance That Is Not ClC-2 or -3 (2004)
Journal Article

PURPOSE. Exposure of organ-cultured lenses to C1- channel blockers under isotonic conditions induces a localized cortical zone of extracellular space dilations. The purpose of this study was to investigate whether elongated lens fiber cells from this... Read More about Cl− Influx into Rat Cortical Lens Fiber Cells Is Mediated by a Cl− Conductance That Is Not ClC-2 or -3.

Organ-specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium (2004)
Journal Article

In the article by Wiles et al. (2004) the wild-type Citrobacter rodentium (and naladixic acid-resistant derivative) strain used was not David Schauer's DBS100 (Schauer et al., 1993) but ICC168 which is a wild-type strain (formally Citrobacter freundi... Read More about Organ-specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium.

Molecular tagging of a senescence gene by introgression mapping of a stay-green mutation from Festuca pratensis (2004)
Journal Article

Intergeneric hybrids between Lolium multiflorum and Festuca pratensis (Lm/Fp) and their derivatives exhibit a unique combination of genetic and cytogenetic characteristics: chromosomes undergo a high frequency of homoeologous recombination at meiosis... Read More about Molecular tagging of a senescence gene by introgression mapping of a stay-green mutation from Festuca pratensis.

Herpes simplex virus VP22-human papillomavirus E2 fusion proteins produced in mammalian or bacterial cells enter mammalian cells and induce apoptotic cell death (2004)
Journal Article

Infection by high‐risk HPV (human papillomavirus) is supposed to be the primary cause of cervical cancer. The HPV E2 protein (E2) is a DNA‐binding protein that regulates viral gene expression and is required for efficient viral replication. Overexpre... Read More about Herpes simplex virus VP22-human papillomavirus E2 fusion proteins produced in mammalian or bacterial cells enter mammalian cells and induce apoptotic cell death.

Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice (2004)
Journal Article

Infection of mice with the intestinal bacterial pathogen Citrobacter rodentium results in colonic mucosal hyperplasia and a local Th1 inflammatory response similar to that seen in mouse models of inflammatory bowel disease. Matrix metalloproteinases... Read More about Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice.

Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays (2004)
Journal Article

Enzymatic activity in the fecal droppings from the house dust mite has been postulated to contribute to the elicited allergic response. Screening dust mite extracts through 137,180 tetrapeptide fluorogenic substrates allowed for the characterization... Read More about Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays.