All Outputs (43)

Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis (2013)
Journal Article
Ashraf, S., Mapp, P. I., Chapman, V., Burston, J., Bennett, A., & Walsh, D. A. (2014). Augmented pain behavioural responses to intra-articular injection of nerve growth factor in two animal models of osteoarthritis. Annals of the Rheumatic Diseases, 73(9), 1710-1718. https://doi.org/10.1136/annrheumdis-2013-203416

Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain (2010)
Journal Article
Sagar, D. R., Staniaszek, L. E., Okine, B. N., Woodhams, S., Norris, L. M., Pearson, R. G., …Chapman, V. (2010). Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. Arthritis and Rheumatism, 62(12), https://doi.org/10.1002/art.27698

Objective. To investigate the impact of an experimental model of osteoarthritis (OA) on spinal nociceptive processing and the role of the inhibitory endocannabinoid system in regulating sensory processing at the spinal level. Methods. Experiment... Read More about Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain.

Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain (2006)
Journal Article
Jhaveri, M., Richardson, D., Kendall, D., Barrett, D., & Chapman, V. (2006). Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain

Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is analgesic in models of acute and inflammatory pain states. The aim of... Read More about Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain.