All Outputs (65)

The Surf-1 and Surf-2 genes and their essential bi-directional promoter elements are conserved between mouse and human (1994)
Journal Article
Lennard, A., Gaston, K., & Fried, M. (1994). The Surf-1 and Surf-2 genes and their essential bi-directional promoter elements are conserved between mouse and human. DNA and Cell Biology, 13(11), 1117-1126. https://doi.org/10.1089/dna.1994.13.1117

The organization of the Surfeit locus and the juxtaposition of at least five of the Surfeit genes (Surf?1 to ?5) are conserved between mouse and human (Williams et al., 1988; Yon et al., 1993). In the mouse, the heterogeneous transcription start site... Read More about The Surf-1 and Surf-2 genes and their essential bi-directional promoter elements are conserved between mouse and human.

YY1 is involved in the regulation of the bi-directional promoter of the Surf-1 and Surf-2 genes (1994)
Journal Article
Gaston, K., & Fried, M. (1994). YY1 is involved in the regulation of the bi-directional promoter of the Surf-1 and Surf-2 genes. FEBS Letters, 347(2-3), 289-294. https://doi.org/10.1016/0014-5793%2894%2900567-2

The Surfeit locus is an unusual cluster of at least 6 housekeeping genes whose organisation is conserved between birds and mammals. We have previously shown that the divergently transcribed Surf?1 and Surf?2 genes are separated by a bi?directional, T... Read More about YY1 is involved in the regulation of the bi-directional promoter of the Surf-1 and Surf-2 genes.

The isolation of transcription factors from ?gt11 cDNA expression libraries: human steroid 5?-reductase 1 has sequence-specific DNA binding activity (1992)
Journal Article
Gaston, K., & Fried, M. (1992). The isolation of transcription factors from ?gt11 cDNA expression libraries: human steroid 5?-reductase 1 has sequence-specific DNA binding activity. Nucleic Acids Research, 20(23), 6297-6301. https://doi.org/10.1093/nar/20.23.6297

The Surf-1/Surf-2 bi-directional promoter contains binding sites for at least three transcription factors (Su1, Su2, and Su3). By screening a ?gt11 HeLa cell cDNA expression library with a concatenated Su2 factor binding site, we isolated a cDNA whic... Read More about The isolation of transcription factors from ?gt11 cDNA expression libraries: human steroid 5?-reductase 1 has sequence-specific DNA binding activity.

A comparison of the DNA bending properties of the DNA binding proteins CRP and TFIID (1992)
Journal Article
Gaston, K., Bell, A., Busby, S., & Fried, M. (1992). A comparison of the DNA bending properties of the DNA binding proteins CRP and TFIID. Nucleic Acids Research, 20(13), 3391-3396. doi:10.1093/nar/20.13.3391

Protein-induced DNA bending is of importance in the formation of complex nucleoprotein assemblies such as those involved in the initiation of DNA replication or transcription initiation. We have compared the DNA bending characteristics of the Escheri... Read More about A comparison of the DNA bending properties of the DNA binding proteins CRP and TFIID.

The nirB promoter of Escherichia coli: location of nucleotide sequences essential for regulation by oxygen, the FNR protein and nitrite (1988)
Journal Article
Jayaraman, P., Gaston, K., Cole, J., & Busby, S. (1988). The nirB promoter of Escherichia coli: location of nucleotide sequences essential for regulation by oxygen, the FNR protein and nitrite. Molecular Microbiology, 2(4), 527-530. https://doi.org/10.1111/j.1365-2958.1988.tb00059.x

Using recombinant DNA techniques, nested deletions have been made upstream of the Escherichia coli nirB transcription start site and their effects on the regulation of nirB promoter activity have been measured. Nucleotide sequences downstream of ?73... Read More about The nirB promoter of Escherichia coli: location of nucleotide sequences essential for regulation by oxygen, the FNR protein and nitrite.