All Outputs (22)

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial (2022)
Journal Article
Butler, C. C., Hobbs, F. D. R., Gbinigie, O. A., Rahman, N. M., Hayward, G., Richards, D. B., Dorward, J., Lowe, D. M., Standing, J. F., Breuer, J., Khoo, S., Petrou, S., Hood, K., Nguyen-Van-Tam, J. S., Patel, M. G., Saville, B. R., Marion, J., Ogburn, E., Allen, J., Rutter, H., …Zafar, A. (2023). Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial. Lancet, 401(10373), 281-293. https://doi.org/10.1016/s0140-6736%2822%2902597-1

Background: The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the community at increased risk of morbidity and mortality from COVID-19. W... Read More about Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.

Burden of respiratory syncytial virus infection in older and high-risk adults: a systematic review and meta-analysis of the evidence from developed countries (2022)
Journal Article
Nguyen-Van-Tam, J. S., O'Leary, M., Martin, E. T., Heijnen, E., Callendret, B., Fleischhackl, R., Comeaux, C., Tran, T. M. P., & Weber, K. (2022). Burden of respiratory syncytial virus infection in older and high-risk adults: a systematic review and meta-analysis of the evidence from developed countries. European Respiratory Review, 31(166), Article 220105. https://doi.org/10.1183/16000617.0105-2022

Background Respiratory syncytial virus (RSV) significantly impacts the health of older and high-risk adults (those with comorbidities). We aimed to synthesise the evidence on RSV disease burden and RSV-related healthcare utilisation in both populatio... Read More about Burden of respiratory syncytial virus infection in older and high-risk adults: a systematic review and meta-analysis of the evidence from developed countries.

Perceptions of the Electronic Holistic Needs Assessment (eHNA) for people with breast cancer: The potential for value or paradox (2022)
Presentation / Conference Contribution
Briggs, L., Corner, J., Bailey, C., & Blake, H. (2022, November). Perceptions of the Electronic Holistic Needs Assessment (eHNA) for people with breast cancer: The potential for value or paradox. Presented at UKONS Annual Conference 2022: Cancer Care in the Digital Age, Belfast, Northern Ireland

Electrochemical Sensor for Ascorbic Acid, Acetaminophen and Nitrite Based on Organoclay/Zr-MOF Film Modified Glassy Carbon Electrode (2022)
Journal Article
Ngwem, M. C. N., Kemmegne‐Mbouguen, J. C., Langmi, H. W., Musyoka, N. M., & Mokaya, R. (2022). Electrochemical Sensor for Ascorbic Acid, Acetaminophen and Nitrite Based on Organoclay/Zr-MOF Film Modified Glassy Carbon Electrode. ChemistrySelect, 7(40), Article e202202308. https://doi.org/10.1002/slct.202202308

A composite (Sa-HTDMA/UiO-66) consisting of organoclay (Sa-HTDMA) and a metal-organic framework (UiO-66) was prepared using organically modified natural Cameroonian clay and Zr-MOF. The organoclay was obtained by intercalating in its interlayer hexad... Read More about Electrochemical Sensor for Ascorbic Acid, Acetaminophen and Nitrite Based on Organoclay/Zr-MOF Film Modified Glassy Carbon Electrode.

Brute force determination of the optimum pore sizes for CO2 uptake in turbostratic carbons (2022)
Journal Article
Blankenship, L. S., Albeladi, N., Alkhaldi, T., Madkhali, A., & Mokaya, R. (2022). Brute force determination of the optimum pore sizes for CO2 uptake in turbostratic carbons. Energy Advances, 1(12), 1009-1020. https://doi.org/10.1039/d2ya00149g

Porosity, and in particular pore size is one of the most important considerations in the development of porous carbons for CO2 capture. Current methods for determining the optimum pore size for adsorption of gases either make very broad assumptions (... Read More about Brute force determination of the optimum pore sizes for CO2 uptake in turbostratic carbons.

A Qualitative Evaluation of the Barriers and Enablers for Implementation of an Asymptomatic SARS-CoV-2 Testing Service at the University of Nottingham: A Multi-Site Higher Education Setting in England (2022)
Journal Article
Blake, H., Somerset, S., Mahmood, I., Mahmood, N., Corner, J., Ball, J. K., & Denning, C. (2022). A Qualitative Evaluation of the Barriers and Enablers for Implementation of an Asymptomatic SARS-CoV-2 Testing Service at the University of Nottingham: A Multi-Site Higher Education Setting in England. International Journal of Environmental Research and Public Health, 19(20), Article 13140. https://doi.org/10.3390/ijerph192013140

Asymptomatic testing for SARS-CoV-2 RNA has been used to prevent and manage COVID-19 outbreaks in university settings, but few studies have explored their implementation. The aim of the study was to evaluate how an accredited asymptomatic SARS-CoV-2... Read More about A Qualitative Evaluation of the Barriers and Enablers for Implementation of an Asymptomatic SARS-CoV-2 Testing Service at the University of Nottingham: A Multi-Site Higher Education Setting in England.

Workforce Experiences of a Rapidly Established SARS-CoV-2 Asymptomatic Testing Service in a Higher Education Setting: A Qualitative Study (2022)
Journal Article
Blake, H., Somerset, S., Mahmood, I., Mahmood, N., Corner, J., Ball, J. K., & Denning, C. (2022). Workforce Experiences of a Rapidly Established SARS-CoV-2 Asymptomatic Testing Service in a Higher Education Setting: A Qualitative Study. International Journal of Environmental Research and Public Health, 19(19), Article 12464. https://doi.org/10.3390/ijerph191912464

The aim of the study was to explore workforce experiences of the rapid implementation of a SARS-CoV-2 asymptomatic testing service (ATS) in a higher education setting during the COVID-19 pandemic. The setting was a multi-campus university in the UK,... Read More about Workforce Experiences of a Rapidly Established SARS-CoV-2 Asymptomatic Testing Service in a Higher Education Setting: A Qualitative Study.

Generalised predictability in the synthesis of biocarbons as clean energy materials: targeted high performance CO2 and CH4 storage (2022)
Journal Article
Alali, I., & Mokaya, R. (2022). Generalised predictability in the synthesis of biocarbons as clean energy materials: targeted high performance CO2 and CH4 storage. Energy and Environmental Science, 15(11), 4710-4724. https://doi.org/10.1039/d2ee02322a

This work shows how knowledge of any biomass and choice of carbonisation process can offer a generalised route to predictability in the preparation of activated biocarbons. We demonstrate that based on O/C ratio of carbonaceous matter, it is possible... Read More about Generalised predictability in the synthesis of biocarbons as clean energy materials: targeted high performance CO2 and CH4 storage.

Lessons learned from 2 years of influenza vaccinations in the UK and USA during the COVID-19 pandemic as respiratory viruses return (2022)
Journal Article
Tan, L. J., Ahmed, S., Rothholz, M. C., Kassianos, G., & Nguyen-Van-Tam, J. S. (2022). Lessons learned from 2 years of influenza vaccinations in the UK and USA during the COVID-19 pandemic as respiratory viruses return. Human Vaccines and Immunotherapeutics, 18(6), Article 2125754. https://doi.org/10.1080/21645515.2022.2125754

During the COVID-19 pandemic, immunization programs for other respiratory infections, notably influenza continued worldwide but attracted less public or political attention than COVID-19 vaccinations. Due to non-pharmaceutical intervention measures t... Read More about Lessons learned from 2 years of influenza vaccinations in the UK and USA during the COVID-19 pandemic as respiratory viruses return.

Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis (2022)
Journal Article
Nakafero, G., Grainge, M. J., Card, T., Mallen, C. D., Nguyen Van-Tam, J. S., Williams, H. C., & Abhishek, A. (2023). Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis. Rheumatology, 62(4), 1445-1450. https://doi.org/10.1093/rheumatology/keac484

OBJECTIVES: To investigate the association between vaccination against coronavirus disease 2019 (COVID-19) and autoimmune rheumatic disease (AIRD) flare.

MATERIAL AND METHODS: Patients with AIRDs vaccinated against COVID-19 who consulted for dise... Read More about Is vaccination against COVID-19 associated with autoimmune rheumatic disease flare? A self-controlled case series analysis.

Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic (2022)
Journal Article
Fuller, A., Hancox, J., Vedhara, K., Card, T., Mallen, C., Van-Tam, J. S. N., & Abhishek, A. (2022). Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic. PLoS ONE, 17(9), Article e0267769. https://doi.org/10.1371/journal.pone.0267769

Objectives To explore barriers and facilitators to COVID-19, influenza, and pneumococcal vaccine uptake in immunosuppressed adults with immune-mediated inflammatory diseases (IMIDs). Methods Recruiting through national patient charities and a local h... Read More about Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic.

Optimization of biodiesel synthesis from Jatropha curcas oil using kaolin derived zeolite Na-X as a catalyst (2022)
Journal Article
Otieno, S., Kengara, F., Kowenje, C., & Mokaya, R. (2022). Optimization of biodiesel synthesis from Jatropha curcas oil using kaolin derived zeolite Na-X as a catalyst. RSC Advances, 12(35), 22792-22805. https://doi.org/10.1039/d2ra03278c

Biodiesel is an alternative renewable green fuel obtainable from the reaction of plant or animal oil with a low molecular weight alcohol in the presence of a catalyst. However, the cost of its production remains high due to costly feedstock, the majo... Read More about Optimization of biodiesel synthesis from Jatropha curcas oil using kaolin derived zeolite Na-X as a catalyst.

Mixed-methods process evaluation of a residence-based SARS-CoV-2 testing participation pilot on a UK university campus during the COVID-19 pandemic (2022)
Journal Article
Blake, H., Carlisle, S., Fothergill, L., Hassard, J., Favier, A., Corner, J., Ball, J. K., & Denning, C. (2022). Mixed-methods process evaluation of a residence-based SARS-CoV-2 testing participation pilot on a UK university campus during the COVID-19 pandemic. BMC Public Health, 22(1), Article 1470. https://doi.org/10.1186/s12889-022-13792-8

Background: Regular testing for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is an important strategy for controlling virus outbreaks on university campuses during the COVID-19 pandemic but testing participation rates can be low. The... Read More about Mixed-methods process evaluation of a residence-based SARS-CoV-2 testing participation pilot on a UK university campus during the COVID-19 pandemic.

Quality Quantification in Deep Convolutional Neural Networks for Skin Lesion Segmentation using Fuzzy Uncertainty Measurement (2022)
Presentation / Conference Contribution
Lin, Q., Chen, X., Chen, C., & Garibaldi, J. M. (2022, July). Quality Quantification in Deep Convolutional Neural Networks for Skin Lesion Segmentation using Fuzzy Uncertainty Measurement. Presented at 2022 IEEE International Conference on Fuzzy Systems (FUZZ-IEEE), Padua, Italy

Deep convolutional neural networks (DCNN)-based methods have achieved promising performance in semantic image segmentation. However, in practical applications, it is important not only to produce the segmentation result but also to inform the segment... Read More about Quality Quantification in Deep Convolutional Neural Networks for Skin Lesion Segmentation using Fuzzy Uncertainty Measurement.

The Rights Track: Sound Evidence on Human Rights and Modern Slavery (2022)
Book
Landman, T., & Garrington, C. (2022). The Rights Track: Sound Evidence on Human Rights and Modern Slavery. Anthem Press

The Rights Track: Sound Evidence on Human Rights and Modern Slavery uses rich content from The Rights Track podcast [www.rightstrack.org] in an innovative book that enhances and enriches our understanding of the human rights challenges facing the wor... Read More about The Rights Track: Sound Evidence on Human Rights and Modern Slavery.

Rational synthesis of microporous carbons for enhanced post-combustion CO2 capture via non-hydroxide activation of air carbonised biomass (2022)
Journal Article
Altwala, A., & Mokaya, R. (2022). Rational synthesis of microporous carbons for enhanced post-combustion CO2 capture via non-hydroxide activation of air carbonised biomass. RSC Advances, 12(31), 20080-20087. https://doi.org/10.1039/d2ra02661a

This work explores the use of a less corrosive activating agent, potassium oxalate (PO), in combination with difficult to activate carbonaceous matter for the preparation of activated carbons. The design of the study allowed a fuller understanding of... Read More about Rational synthesis of microporous carbons for enhanced post-combustion CO2 capture via non-hydroxide activation of air carbonised biomass.

Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial (2022)
Journal Article
Abhishek, A., Boyton, R. J., Peckham, N., McKnight, Á., Coates, L. C., Bluett, J., Barber, V., Cureton, L., Francis, A., Appelbe, D., Eldridge, L., Julier, P., Valdes, A. M., Brooks, T., Rombach, I., Altmann, D. M., Nguyen-Van-Tam, J. S., Williams, H. C., & Cook, J. A. (2022). Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial. Lancet Respiratory Medicine, 10(9), 840-850. https://doi.org/10.1016/S2213-2600%2822%2900186-2

Background: Immunosuppressive treatments inhibit vaccine-induced immunity against SARS-CoV-2. We evaluated whether a 2-week interruption of methotrexate treatment immediately after the COVID-19 vaccine booster improved antibody responses against the... Read More about Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial.

Exploring the Psychological Impacts of COVID-19 Social Restrictions on International University Students: A Qualitative Study (2022)
Journal Article
Al-Oraibi, A., Fothergill, L., Yildirim, M., Knight, H., Carlisle, S., O’Connor, M., Briggs, L., Morling, J. R., Corner, J., Ball, J. K., Denning, C., Vedhara, K., & Blake, H. (2022). Exploring the Psychological Impacts of COVID-19 Social Restrictions on International University Students: A Qualitative Study. International Journal of Environmental Research and Public Health, 19(13), Article 7631. https://doi.org/10.3390/ijerph19137631

The global COVID-19 pandemic has impacted on the mental well-being of university students, but little attention has been given to international students, who may have a unique experience and perspective. The aim of this study was to explore the views... Read More about Exploring the Psychological Impacts of COVID-19 Social Restrictions on International University Students: A Qualitative Study.

Ethical Concerns and Perceptions of Consumer Neurotechnology from Lived Experiences of Mental Workload Tracking (2022)
Presentation / Conference Contribution
Midha, S., Wilson, M. L., & Sharples, S. (2022, June). Ethical Concerns and Perceptions of Consumer Neurotechnology from Lived Experiences of Mental Workload Tracking. Presented at FAccT '22: 2022 ACM Conference on Fairness, Accountability, and Transparency, Seoul Republic of Korea

With rapid growth in the development of consumer neurotechnology, it is imperative to consider the ethical implications that this might have in order to minimise consumer harm. Whilst ethical and legal guidelines for commercialisation have previously... Read More about Ethical Concerns and Perceptions of Consumer Neurotechnology from Lived Experiences of Mental Workload Tracking.

Aid effectiveness: Human rights as a conditionality measure (2022)
Journal Article
Douch, M., Edwards, H., Landman, T., & Mallick, S. (2022). Aid effectiveness: Human rights as a conditionality measure. World Development, 158, Article 105978. https://doi.org/10.1016/j.worlddev.2022.105978

The ‘aid conditionality’ hypothesis as documented in the literature suggests that aid is effective in augmenting growth only in the presence of a sound policy environment. This hypothesis was so influential that its policy recommendation, to provide... Read More about Aid effectiveness: Human rights as a conditionality measure.