Electrochemical Sensor for Ascorbic Acid, Acetaminophen and Nitrite Based on Organoclay/Zr-MOF Film Modified Glassy Carbon Electrode

Ngwem, Marcelline Carine Ngo; Kemmegne‐Mbouguen, Justin Claude; Langmi, Henrietta W.; Musyoka, Nicholas M.; Mokaya, Robert

Abstract

A composite (Sa-HTDMA/UiO-66) consisting of organoclay (Sa-HTDMA) and a metal-organic framework (UiO-66) was prepared using organically modified natural Cameroonian clay and Zr-MOF. The organoclay was obtained by intercalating in its interlayer hexadecyltrimethyl ammonium cation (HTDMA). The composite was then used to form a film onto a glassy carbon electrode (GCE) by drop coating (Sa-HTDMA/UiO-66/GCE). Electrochemical responses recorded at the as-prepared modified electrodes for ascorbic acid (AA), acetaminophen (AC) and nitrite (NO2−) were investigated using cyclic and linear sweep voltammetry. The results revealed that Sa-HTDMA/UiO-66/GCE exhibited a favorable behavior for individual and simultaneous sensing of AA, AC and NO2−. Additionally, compared with UiO-66 modified GCE, the composite enabled good performance of the electrode. Under the optimum conditions, the linear calibration curves were attained in the following ranges: 1–650 μM for AA, 1–700 μM for AC and 1–600 μM for NO2− with the respective detection limits of 0.01, 0.19 and 0.33 μM. Application of the sensors to determine AA and AC in pharmaceutical preparations, and NO2− in tap water, was successful.

Citation

Ngwem, M. C. N., Kemmegne‐Mbouguen, J. C., Langmi, H. W., Musyoka, N. M., & Mokaya, R. (2022). Electrochemical Sensor for Ascorbic Acid, Acetaminophen and Nitrite Based on Organoclay/Zr-MOF Film Modified Glassy Carbon Electrode. ChemistrySelect, 7(40), Article e202202308. https://doi.org/10.1002/slct.202202308

• Journal Article Type: Article
• Acceptance Date: Oct 6, 2022
• Online Publication Date: Oct 25, 2022
• Publication Date: Oct 26, 2022
• Deposit Date: Nov 3, 2022
• Publicly Available Date: Oct 26, 2023
• Journal: ChemistrySelect
• Electronic ISSN: 2365-6549
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 7
• Issue: 40
• Article Number: e202202308
• DOI: https://doi.org/10.1002/slct.202202308
• Public URL: https://nottingham-repository.worktribe.com/output/13176910
• Publisher URL: https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/slct.202202308
• Additional Information: This is the peer reviewed version of the following article: M. C. N. Ngwem, J. C. Kemmegne-Mbouguen, H. W. Langmi, N. M. Musyoka, R. Mokaya, ChemistrySelect 2022, 7, e202202308, which has been published in final form at https://doi.org/10.1002/slct.202202308. The article must be linked to Wiley’s version of record on Wiley Online Library