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Electrochemical Sensor for Ascorbic Acid, Acetaminophen and Nitrite Based on Organoclay/Zr-MOF Film Modified Glassy Carbon Electrode

Ngwem, Marcelline Carine Ngo; Kemmegne‐Mbouguen, Justin Claude; Langmi, Henrietta W.; Musyoka, Nicholas M.; Mokaya, Robert

Authors

Marcelline Carine Ngo Ngwem

Justin Claude Kemmegne‐Mbouguen

Henrietta W. Langmi

Nicholas M. Musyoka



Abstract

A composite (Sa-HTDMA/UiO-66) consisting of organoclay (Sa-HTDMA) and a metal-organic framework (UiO-66) was prepared using organically modified natural Cameroonian clay and Zr-MOF. The organoclay was obtained by intercalating in its interlayer hexadecyltrimethyl ammonium cation (HTDMA). The composite was then used to form a film onto a glassy carbon electrode (GCE) by drop coating (Sa-HTDMA/UiO-66/GCE). Electrochemical responses recorded at the as-prepared modified electrodes for ascorbic acid (AA), acetaminophen (AC) and nitrite (NO2−) were investigated using cyclic and linear sweep voltammetry. The results revealed that Sa-HTDMA/UiO-66/GCE exhibited a favorable behavior for individual and simultaneous sensing of AA, AC and NO2−. Additionally, compared with UiO-66 modified GCE, the composite enabled good performance of the electrode. Under the optimum conditions, the linear calibration curves were attained in the following ranges: 1–650 μM for AA, 1–700 μM for AC and 1–600 μM for NO2− with the respective detection limits of 0.01, 0.19 and 0.33 μM. Application of the sensors to determine AA and AC in pharmaceutical preparations, and NO2− in tap water, was successful.

Citation

Ngwem, M. C. N., Kemmegne‐Mbouguen, J. C., Langmi, H. W., Musyoka, N. M., & Mokaya, R. (2022). Electrochemical Sensor for Ascorbic Acid, Acetaminophen and Nitrite Based on Organoclay/Zr-MOF Film Modified Glassy Carbon Electrode. ChemistrySelect, 7(40), Article e202202308. https://doi.org/10.1002/slct.202202308

Journal Article Type Article
Acceptance Date Oct 6, 2022
Online Publication Date Oct 25, 2022
Publication Date Oct 26, 2022
Deposit Date Nov 3, 2022
Publicly Available Date Mar 29, 2024
Journal ChemistrySelect
Electronic ISSN 2365-6549
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 7
Issue 40
Article Number e202202308
DOI https://doi.org/10.1002/slct.202202308
Public URL https://nottingham-repository.worktribe.com/output/13176910
Publisher URL https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/slct.202202308
Additional Information This is the peer reviewed version of the following article: M. C. N. Ngwem, J. C. Kemmegne-Mbouguen, H. W. Langmi, N. M. Musyoka, R. Mokaya, ChemistrySelect 2022, 7, e202202308, which has been published in final form at https://doi.org/10.1002/slct.202202308. The article must be linked to Wiley’s version of record on Wiley Online Library

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