The adaptability of the ion binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF

Lithgo, Ryan M.; Hanževački, Marko; Harris, Gemma; Kamps, Jos J .A. G.; Holden, Ellie; Gianga, Tiberiu-Marius; Benesch, Justin L.P.; Jäger, Christof M.; Croft, Anna K.; Hussain, Rohannah; Hobman, Jon L.; Orville, Allen M.; Quigley, Andrew; Carr, Stephen B.; Scott, David J.

doi:10.1016/j.jbc.2023.105331

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The adaptability of the ion binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF (2023)
Journal Article
Lithgo, R. M., Hanževački, M., Harris, G., Kamps, J. J. .. G., Holden, E., Gianga, T., …Scott, D. J. (2023). The adaptability of the ion binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF. Journal of Biological Chemistry, 299(11), Article 105331. https://doi.org/10.1016/j.jbc.2023.105331

The periplasmic chaperone SilF has been identified as part of an Ag(I) detoxification system in Gram negative bacteria. Sil proteins also bind Cu(I), but with reported weaker affinity, therefore leading to the designation of a specific detoxification... Read More about The adaptability of the ion binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF.