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Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites (2023)
Journal Article
Fry, A., White, B., Nagarwalla, D., Shelton, J., & Jack, R. H. (2023). Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites. BMJ Open, 13(1), Article e062079. https://doi.org/10.1136/bmjopen-2022-062079

Objectives: Cancer stage at diagnosis is a determinant of treatment options and survival. Previous research has shown differences in barriers to presentation with cancer between ethnic groups. The completeness and quality of cancer stage and ethnicit... Read More about Relationship between ethnicity and stage at diagnosis in England: a national analysis of six cancer sites.

Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated (2023)
Journal Article
Atallah, E., Grove, J. I., Crooks, C., Burden-Teh, E., Abhishek, A., Moreea, S., …Aithal, G. P. (2023). Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated. Journal of Hepatology, 78(5), 989-997. https://doi.org/10.1016/j.jhep.2022.12.034

Background & Aims: The risk of significant liver fibrosis from prolonged methotrexate (MTX) exposure has been estimated at around 5%, prompting intensive monitoring strategies. However, the evidence is derived from retrospective studies that under-re... Read More about Risk of liver fibrosis associated with long-term methotrexate therapy may be overestimated.

Characterisation of the Paternal Influence on Intergenerational Offspring Cardiac and Brain Lipid Homeostasis in Mice (2023)
Journal Article
Furse, S., Morgan, H. L., Koulman, A., & Watkins, A. J. (2023). Characterisation of the Paternal Influence on Intergenerational Offspring Cardiac and Brain Lipid Homeostasis in Mice. International Journal of Molecular Sciences, 24(3), Article 1814. https://doi.org/10.3390/ijms24031814

There is growing evidence that poor paternal diet at the time of conception increase the risk of offspring developing a range of non-communicable metabolic diseases, such as obesity, diabetes and cardiovascular disease, in adulthood. We hypothesise t... Read More about Characterisation of the Paternal Influence on Intergenerational Offspring Cardiac and Brain Lipid Homeostasis in Mice.

The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review (2023)
Journal Article
Phillips, O., Baguley, D., Pearson, S., & Akeroyd, M. A. (2023). The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review. Journal of Cancer Survivorship, 17(1), 40-58. https://doi.org/10.1007/s11764-022-01314-9

Purpose: To elucidate the long-term impacts of hearing loss, tinnitus and balance in people living with and beyond cancer (LWBC) treated with platinum-based chemotherapy (PBCT). Methods: A literature search was conducted between March and June 2022 u... Read More about The long-term impacts of hearing loss, tinnitus and poor balance on the quality of life of people living with and beyond cancer after platinum-based chemotherapy: a literature review.

The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets (2023)
Journal Article
Gysling, S., Morgan, H., Ifesemen, O. S., West, D., Conibear, J., Navani, N., …Hubbard, R. (2023). The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets. Chest, 163(6), 1599-1607. https://doi.org/10.1016/j.chest.2023.01.008

Background: The COVID-19 pandemic has caused significant disruption to health-care services and delivery worldwide. The impact of the pandemic and associated national lockdowns on lung cancer incidence in England have yet to be assessed. Research Que... Read More about The Impact of COVID-19 on Lung Cancer Incidence in England: Analysis of the National Lung Cancer Audit 2019 and 2020 Rapid Cancer Registration Datasets.

A Qualitative Study of the Implementation and Continued Delivery of Complete and Partial Smoke-Free Policies Across England's Prison Estate (2023)
Journal Article
Jayes, L., Waddingham, J., Britton, J., & Murray, R. (2023). A Qualitative Study of the Implementation and Continued Delivery of Complete and Partial Smoke-Free Policies Across England's Prison Estate. Nicotine & Tobacco Research, 25(6), 1099-1108. https://doi.org/10.1093/ntr/ntac296

Introduction In the UK, smoking among prisoners is up to five times more prevalent than the national average. Between 2015 and 2018, HMPPS introduced a complete smoke-free policy in all closed prisons, and a partial policy permitting smoking only in... Read More about A Qualitative Study of the Implementation and Continued Delivery of Complete and Partial Smoke-Free Policies Across England's Prison Estate.

Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring: Part 1 wearable technology (2023)
Journal Article
Grooby, E., Sitaula, C., Chang Kwok, T., Sharkey, D., Marzbanrad, F., & Malhotra, A. (2023). Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring: Part 1 wearable technology. Pediatric Research, 93(2), 413-425. https://doi.org/10.1038/s41390-022-02416-x

Abstract: With the development of Artificial Intelligence techniques, smart health monitoring is becoming more popular. In this study, we investigate the trend of wearable sensors being adopted and developed in neonatal cardiorespiratory monitoring.... Read More about Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring: Part 1 wearable technology.

Analgesic utilization in people with knee osteoarthritis: A population-based study using primary care data (2023)
Journal Article
Taqi, A., Gran, S., & Knaggs, R. D. (2023). Analgesic utilization in people with knee osteoarthritis: A population-based study using primary care data. Pain Practice, https://doi.org/10.1111/papr.13212

Purpose: Osteoarthritis (OA) is a chronic painful condition that often affects large joints such as the knee. Treatment guidelines recommend paracetamol, nonsteroidal anti-inflammatory drugs (NSAIDs), and opioids. Antidepressants and anti-epileptic d... Read More about Analgesic utilization in people with knee osteoarthritis: A population-based study using primary care data.

Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset (2022)
Journal Article
Sisodia, S., McGill, S., Evans, M. S., Brough, G., Okereke, U., & Dunn, T. J. (2023). Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset. Public Health In Practice, 5, Article 100351. https://doi.org/10.1016/j.puhip.2022.100351

Objectives To capture and compare the differences in experiences of public health Specialty Registrars who commenced training prior to the COVID-19 pandemic (pre-pandemic Registrars) and those who commenced training during the pandemic (post-pandemi... Read More about Comparing impacts of the COVID-19 pandemic on training of public health Specialty Registrars starting before or after its onset.

Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context (2022)
Journal Article
Quinn-Scoggins, H. D., Murray, R. L., Quaife, S. L., Smith, P., Brain, K. E., Callister, M. E. J., …McCutchan, G. M. (2022). Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context. BMC Pulmonary Medicine, 22(1), Article 478. https://doi.org/10.1186/s12890-022-02263-w

Background: Optimising smoking cessation services within a low radiation-dose computed tomography (LDCT) lung cancer screening programme has the potential to improve cost-effectiveness and overall efficacy of the programme. However, evidence on the o... Read More about Co-development of an evidence-based personalised smoking cessation intervention for use in a lung cancer screening context.

Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence (2022)
Journal Article
Sitaula, C., Grooby, E., Kwok, T. C., Sharkey, D., Marzbanrad, F., & Malhotra, A. (2023). Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence. Pediatric Research, 93(2), 426-436. https://doi.org/10.1038/s41390-022-02417-w

Background: With the development of Artificial Intelligence (AI) techniques, smart health monitoring, particularly neonatal cardiorespiratory monitoring with wearable devices, is becoming more popular. To this end, it is crucial to investigate the tr... Read More about Artificial intelligence-driven wearable technologies for neonatal cardiorespiratory monitoring. Part 2: artificial intelligence.

Techniques for managing an impacted fetal head at caesarean section: A systematic review (2022)
Journal Article
Peak, A. G., Barwise, E., & Walker, K. F. (2023). Techniques for managing an impacted fetal head at caesarean section: A systematic review. European Journal of Obstetrics and Gynecology and Reproductive Biology, 281, 12-22. https://doi.org/10.1016/j.ejogrb.2022.12.017

A complication arising at caesarean birth when the baby's head is deeply engaged in the pelvis and may be difficult to deliver, is known as an ‘impacted fetal head’. This obstetric emergency occurs in 16% of second stage caesarean sections. Multiple... Read More about Techniques for managing an impacted fetal head at caesarean section: A systematic review.

Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials (2022)
Journal Article
Santer, M., Muller, I., Becque, T., Stuart, B., Hooper, J., Steele, M., …Thomas, K. S. (2022). Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials. BMJ, 379, Article e072007. https://doi.org/10.1136/bmj-2022-072007

Objective: To determine the effectiveness of two online behavioural interventions, one for parents and carers and one for young people, to support eczema self-management. Design: Two independent, pragmatic, parallel group, unmasked, randomised contro... Read More about Eczema Care Online behavioural interventions to support self-care for children and young people: two independent, pragmatic, randomised controlled trials.

'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema (2022)
Journal Article
Greenwell, K., Sivyer, K., Howells, L., Steele, M., Ridd, M. J., Roberts, A., …Muller, I. (2023). 'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema. British Journal of Dermatology, 188(4), 506-513. https://doi.org/10.1093/bjd/ljac115

Background There is a lack of well-conducted randomized controlled trials evaluating the effectiveness of theory-based online interventions for eczema. To address these deficiencies, we previously developed and demonstrated the effectiveness of two o... Read More about 'Eczema shouldn't control you; you should control eczema': qualitative process evaluation of online behavioural interventions to support young people and parents/carers of children with eczema.

Emollients for prevention of atopic dermatitis: 5‐year findings from the BEEP randomized trial (2022)
Journal Article
Bradshaw, L. E., Wyatt, L. A., Brown, S. J., Haines, R. H., Montgomery, A. A., Perkin, M. R., …Williams, H. C. (2023). Emollients for prevention of atopic dermatitis: 5‐year findings from the BEEP randomized trial. Allergy, 78(4), 995-1006. https://doi.org/10.1111/all.15555

Background: The effectiveness of emollients for preventing atopic dermatitis/eczema is controversial. The Barrier Enhancement for Eczema Prevention trial evaluated the effects of daily emollients during the first year of life on atopic dermatitis and... Read More about Emollients for prevention of atopic dermatitis: 5‐year findings from the BEEP randomized trial.

The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” Project: a protocol for the development of the core outcome domain set for trials in pyoderma gangrenosum (2022)
Journal Article
Rick, J., Gould, L. J., Marzano, A. V., Garg, A., Chen, D., Oakes, D. L., …Ortega-Loayza, A. G. (2023). The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” Project: a protocol for the development of the core outcome domain set for trials in pyoderma gangrenosum. Archives of Dermatological Research, 315(4), 983-988. https://doi.org/10.1007/s00403-022-02424-1

Introduction: Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that affects approximately 0.3–6 out of every 100,000 people worldwide. Clinical trials are scarce but there is growing interest in using newer and more targeted therapeutics t... Read More about The “Understanding Pyoderma Gangrenosum, Review and Assessment of Disease Effects (UPGRADE)” Project: a protocol for the development of the core outcome domain set for trials in pyoderma gangrenosum.

Effects of mobile technology-based interventions for promoting mental health and psychosocial well-being among young people in low- and middle-income countries: a systematic review protocol (2022)
Journal Article
Rai, D., Bhattacharjee, S., Dhakal, R., Chattopadhyay, K., & Neupane, D. (2023). Effects of mobile technology-based interventions for promoting mental health and psychosocial well-being among young people in low- and middle-income countries: a systematic review protocol. JBI Evidence Synthesis, 21(4), 744-752. https://doi.org/10.11124/JBIES-22-00034

Objective: This review will aim to examine the effectiveness of mobile-based technologies implemented in low-and middle-income countries (LMICs) among young people (10-24 years) to promote their mental health and psychosocial wellbeing. Such promotio... Read More about Effects of mobile technology-based interventions for promoting mental health and psychosocial well-being among young people in low- and middle-income countries: a systematic review protocol.

Risk of Suicide After Dementia Diagnosis (2022)
Journal Article
Alothman, D., Card, T., Lewis, S., Tyrrell, E., Fogarty, A. W., & Marshall, C. R. (2022). Risk of Suicide After Dementia Diagnosis. JAMA Neurology, 79(11), 1148-1154. https://doi.org/10.1001/jamaneurol.2022.3094

Importance: Patients with dementia may be at an increased suicide risk. Identifying groups at greatest risk of suicide would support targeted risk reduction efforts by clinical dementia services. Objectives: To examine the association between a d... Read More about Risk of Suicide After Dementia Diagnosis.