All Outputs (350)

Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study (2023)
Journal Article

Background: Higher-valency pneumococcal vaccines are anticipated. We aimed to describe serotype distribution and risk factors for vaccine-serotype community-acquired pneumonia (CAP) in the two years pre-SARS-CoV-2 pandemic. Methods: We conducted a pr... Read More about Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study.

How Should a Vape Shop-Based Smoking Cessation Intervention Be Delivered? A Qualitative Study (2023)
Journal Article

Introduction Encouraging smokers to quit smoking tobacco using e-cigarettes could substantially reduce smoking-related diseases. Vape shops (VS) therefore have the potential to play an important role in supporting smoking cessation. The aim of thi... Read More about How Should a Vape Shop-Based Smoking Cessation Intervention Be Delivered? A Qualitative Study.

International melanoma and non melanoma skin cancer mortality trends: is it time to refocus our attention? (2023)
Journal Article

Treatment of Hidradenitis Suppurativa Evaluation Study: the THESEUS prospective cohort study (2023)
Journal Article

Background Hidradenitis suppurativa is a chronic inflammatory skin disease characterised by recurrent inflammatory lesions and skin tunnels in flexural sites such as the axilla. Deroofing of skin tunnels and laser treatment are standard hidradenit... Read More about Treatment of Hidradenitis Suppurativa Evaluation Study: the THESEUS prospective cohort study.

Evidence-based appraisal of the role of SJTs in selection (2023)
Journal Article

A recent opinion article in Clinical Medicine promoted a new preference-based algorithm to allocate training places for the UK Foundation Programme Office (UKFPO). This replaced the previous process, which ranked candidates based on medical school ac... Read More about Evidence-based appraisal of the role of SJTs in selection.

Embedding genomics across the NHS: a primary care perspective (2023)
Journal Article

Primary care remains the point of access to the NHS as well as having key roles in care coordination and prescribing. Therefore, embedding of genomic medicine in the NHS relies on successful implementation into the primary care landscape. Primary car... Read More about Embedding genomics across the NHS: a primary care perspective.

Antibody response to four doses of SARS-CoV-2 vaccine in rare autoimmune rheumatic diseases: an observational study (2023)
Journal Article

Objective: Antibody responses to coronavirus disease 2019 (COVID-19) vaccines are reduced among immunocompromised patients but are not well quantified among people with rare disease. We conducted an observational study to evaluate the antibody respon... Read More about Antibody response to four doses of SARS-CoV-2 vaccine in rare autoimmune rheumatic diseases: an observational study.

Assessment of ethnic inequalities in diagnostic coding of familial hypercholesterolaemia (FH): A cross-sectional database study in Lambeth, South London (2023)
Journal Article

Background and aims: Differences in the perceived prevalence of familial hypercholesterolemia (FH) by ethnicity are unclear. In this study, we aimed to assess the prevalence, determinants and management of diagnostically-coded FH in an ethnically div... Read More about Assessment of ethnic inequalities in diagnostic coding of familial hypercholesterolaemia (FH): A cross-sectional database study in Lambeth, South London.

Experiences of coordinated care for people in the UK affected by rare diseases: cross-sectional survey of patients, carers, and healthcare professionals (2023)
Journal Article

Background Poorly coordinated care can have major impacts on patients and families affected by rare conditions, with negative physical health, psychosocial and financial consequences. This study aimed to understand how care is coordinated for rare d... Read More about Experiences of coordinated care for people in the UK affected by rare diseases: cross-sectional survey of patients, carers, and healthcare professionals.

Eczema Bathing Study – how often should we bathe? (2023)
Dataset

Background and study aims The Eczema Bathing Study is part of the Rapid Eczema Trials project. The researchers hope to answer many questions about how to manage eczema through this project. People with eczema are helping to prioritise, design and ru... Read More about Eczema Bathing Study – how often should we bathe?.

Assessing the value of integrating national longitudinal shopping data into respiratory disease forecasting models (2023)
Journal Article

The COVID-19 pandemic led to unparalleled pressure on healthcare services. Improved healthcare planning in relation to diseases affecting the respiratory system has consequently become a key concern. We investigated the value of integrating sales of... Read More about Assessing the value of integrating national longitudinal shopping data into respiratory disease forecasting models.

Using a machine learning model to risk stratify for the presence of significant liver disease in a primary care population (2023)
Journal Article

Background: Current strategies for detecting significant chronic liver disease (CLD) in the community are based on the extrapolation of diagnostic tests used in secondary care settings. Whilst this approach provides clinical utility, it has limitatio... Read More about Using a machine learning model to risk stratify for the presence of significant liver disease in a primary care population.

Lifestyle behaviours and associated factors among people with type 2 diabetes attending a diabetes clinic in Ningbo, China: A crosssectional study (2023)
Journal Article

The burden of type 2 diabetes (T2DM) in China is significant and growing, and this is reflected in high rates of T2DM in the city of Ningbo, China. Consequent impacts on morbidity, mortality, healthcare expenditure, and health-related quality of life... Read More about Lifestyle behaviours and associated factors among people with type 2 diabetes attending a diabetes clinic in Ningbo, China: A crosssectional study.

‘No evidence of harm’ implies no evidence of safety: Framing the lack of causal evidence in gambling advertising research (2023)
Journal Article

A core domain set for pyoderma gangrenosum trial outcomes: an international eDelphi and consensus study from the UPGRADE initiative (2023)
Journal Article

Background Pyoderma gangrenosum (PG) is a rare ulcerative skin condition with no current standardized outcomes or outcome measures. With a rich investigational therapeutic pipeline, standardization of outcomes and improvement of data quality and inte... Read More about A core domain set for pyoderma gangrenosum trial outcomes: an international eDelphi and consensus study from the UPGRADE initiative.

Qualitative Investigation of the Novel Use of Shopping Loyalty Card Data in Medical Decision Making (2023)
Book Chapter

This paper describes early results of a small qualitative study investigating the potential impact of shopping loyalty card data (SLCD) in the diagnostic pathway for ovarian cancer. There is early evidence that pharmaceutical products such as pain re... Read More about Qualitative Investigation of the Novel Use of Shopping Loyalty Card Data in Medical Decision Making.

The critical role of technologies in neonatal care (2023)
Journal Article

Neonatal care has made significant advances in the last few decades. As a result, mortality and morbidity in high-risk infants, such as extremely preterm infants or those infants with birth-related brain injury, has reduced significantly. Many of the... Read More about The critical role of technologies in neonatal care.

Association between women’s experience of domestic violence and childhood vaccination in West Africa: Cross-sectional analysis of Demographic and Health Survey data (2023)
Journal Article

Background: In 2021, 25 million children worldwide did not receive full basic childhood vaccinations, the highest figure in over a decade. There are large variations between countries in vaccination coverage. Globally, the lifetime prevalence of dome... Read More about Association between women’s experience of domestic violence and childhood vaccination in West Africa: Cross-sectional analysis of Demographic and Health Survey data.

Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data (2023)
Journal Article

Background There is an increasing demand for mental health services for young people, which may vary across the year. Objective To determine whether there are seasonal patterns in primary care antidepressant prescribing and mental health issues in... Read More about Seasonal trends in antidepressant prescribing, depression, anxiety and self-harm in adolescents and young adults: an open cohort study using English primary care data.

Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound‐guided intra‐articular hip injection in the hip injection trial. A qualitative study (2023)
Journal Article

Objectives: The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound-guided intra-articular injection of either corticosteroid and local anaesthetic or local anaesthetic alone to advice and education among people with hi... Read More about Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound‐guided intra‐articular hip injection in the hip injection trial. A qualitative study.