Re: Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case Control Study
(2019)
Journal Article
All Outputs (350)
Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review (2019)
Journal Article
Background & aims Weight loss is common in people with neurodegenerative diseases of the motor system (NDMS), such as Parkinson's disease and Amyotrophic Lateral Sclerosis, and is associated with reduced quality of life, functional ability and survi... Read More about Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review.
An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units (2019)
Journal Article
Background Good Clinical Practice guidelines issued in 2016 encourage risk-based approaches to monitoring clinical trials. This study compared current risk assessment and monitoring approaches in UK Clinical Trials Units (CTUs) with the published gu... Read More about An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units.
Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study (2019)
Journal Article
IMPORTANCE Anticholinergic medicines have short-term cognitive adverse effects, but it is uncertain whether long-term use of these drugs is associated with an increased risk of dementia. OBJECTIVE To assess associations between anticholinergic dr... Read More about Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study.
Origins of lifetime health around the time of conception: causes and consequences (2018)
Journal Article
Parental environmental factors, including diet, body composition, metabolism, and stress, affect the health and chronic disease risk of people throughout their lives, as captured in the Developmental Origins of Health and Disease concept. Research ac... Read More about Origins of lifetime health around the time of conception: causes and consequences.
Interventions made by UK pharmacists to minimise risk from paediatric prescribing errors (2016)
Journal Article
The PAndemic INfluenza Triage in the Emergency Department (PAINTED) pilot cohort study (2015)
Journal Article
Background Research needs to be undertaken rapidly in the event of an influenza pandemic to develop and evaluate triage methods for people presenting to the emergency department with suspected pandemic influenza. Objectives We aimed to pilot a r... Read More about The PAndemic INfluenza Triage in the Emergency Department (PAINTED) pilot cohort study.
Maternal Obesity and Infant Mortality: A Meta-Analysis (2014)
Journal Article
BACKGROUND AND OBJECTIVES: Despite numerous studies reporting an elevated risk of infant mortality among women who are obese, the magnitude of the association is unclear. A systematic review and meta-analysis was undertaken to assess the association... Read More about Maternal Obesity and Infant Mortality: A Meta-Analysis.
How to read a cohort study (2014)
Book Chapter
The cohort is the basis of all epidemiologic study designs as it is the closest way to study the natural progression of people's life course over which the temporal relationship between exposures and outcomes can be assessed. Although a cohort is def... Read More about How to read a cohort study.
How to read a case-control study (2014)
Book Chapter
Background It is good practice for the public to be involved in developing health research. Resources should be available for researchers to fund the involvement of the public in the development of their grants. Objective To describe a funding a... Read More about Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS).
Act now against new NHS competition regulations (2013)
Journal Article
An open letter to the BMA and the Academy of Medical Royal Colleges calls on them to make a joint public statement of opposition to the amended section 75 regulations
Children's access to medicines (2012)
Journal Article
Sunday 13 November - Short paper session 2: Children's access to medicines
Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK) (2011)
Journal Article
Background Low levels of physical activity in children have been linked to an increased risk of obesity, but many children lack confidence in relation to exercise (exercise self-efficacy). Factors which can impact on confidence include a chronic hea... Read More about Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK).
Acute medical unit comprehensive geriatric assessment intervention study (AMIGOS): Study protocol for a randomised controlled trial (2011)
Journal Article
Background Many older people presenting to Acute Medical Units (AMU) are discharged after only a short stay (< 72 hours), yet many re-present to hospital or die within 1 year. Comprehensive Geriatric Assessment may improve patient outcomes for this... Read More about Acute medical unit comprehensive geriatric assessment intervention study (AMIGOS): Study protocol for a randomised controlled trial.
Garlic as an inhibitor of pseudomonas aeruginosa quorum sensing in cystic fibrosis - A pilot randomized controlled trial (2010)
Journal Article
Pseudomonas aeruginosa forms biofilms in the cystic fibrosis lung. Quorum sensing (QS) controls biofilm maturation, immune evasion, antibiotic tolerance and virulence factor production. Garlic shows QS inhibitory activity in vitro and in animal model... Read More about Garlic as an inhibitor of pseudomonas aeruginosa quorum sensing in cystic fibrosis - A pilot randomized controlled trial.
Clinical trials: the viewpoint of children with a chronic illness compared with healthy children (2009)
Journal Article
The views of over 200 children (11–16 years old, who were either healthy or attending paediatric medical clinics with a chronic illness) on issues relating to paediatric clinical trials were determined by a questionnaire. Children with a chronic illn... Read More about Clinical trials: the viewpoint of children with a chronic illness compared with healthy children.