All Outputs (325)

Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review (2019)
Journal Article

Background & aims Weight loss is common in people with neurodegenerative diseases of the motor system (NDMS), such as Parkinson's disease and Amyotrophic Lateral Sclerosis, and is associated with reduced quality of life, functional ability and survi... Read More about Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review.

An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units (2019)
Journal Article

Background Good Clinical Practice guidelines issued in 2016 encourage risk-based approaches to monitoring clinical trials. This study compared current risk assessment and monitoring approaches in UK Clinical Trials Units (CTUs) with the published gu... Read More about An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units.

ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol (2019)
Journal Article

Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study (2019)
Journal Article

IMPORTANCE Anticholinergic medicines have short-term cognitive adverse effects, but it is uncertain whether long-term use of these drugs is associated with an increased risk of dementia. OBJECTIVE To assess associations between anticholinergic dr... Read More about Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study.

P018 RENAL adverse events and gastrointestinal bleeding with ibuprofen use in preterm neonates with patent ductus arteriosus (PDA) (2019)
Journal Article

Origins of lifetime health around the time of conception: causes and consequences (2018)
Journal Article

Parental environmental factors, including diet, body composition, metabolism, and stress, affect the health and chronic disease risk of people throughout their lives, as captured in the Developmental Origins of Health and Disease concept. Research ac... Read More about Origins of lifetime health around the time of conception: causes and consequences.

368 CFHealthHub: development and evaluation of videos incorporating peer description of successful self-management with inhaled therapies in adults with CF used to build self-efficacy to support self-care within the CFHealthHub complex intervention (2017)
Journal Article

Interventions made by UK pharmacists to minimise risk from paediatric prescribing errors (2016)
Journal Article

The PAndemic INfluenza Triage in the Emergency Department (PAINTED) pilot cohort study (2015)
Journal Article

Background Research needs to be undertaken rapidly in the event of an influenza pandemic to develop and evaluate triage methods for people presenting to the emergency department with suspected pandemic influenza. Objectives We aimed to pilot a r... Read More about The PAndemic INfluenza Triage in the Emergency Department (PAINTED) pilot cohort study.

Maternal Obesity and Infant Mortality: A Meta-Analysis (2014)
Journal Article

BACKGROUND AND OBJECTIVES: Despite numerous studies reporting an elevated risk of infant mortality among women who are obese, the magnitude of the association is unclear. A systematic review and meta-analysis was undertaken to assess the association... Read More about Maternal Obesity and Infant Mortality: A Meta-Analysis.

Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS) (2013)
Journal Article

Background It is good practice for the public to be involved in developing health research. Resources should be available for researchers to fund the involvement of the public in the development of their grants. Objective To describe a funding a... Read More about Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS).

Act now against new NHS competition regulations (2013)
Journal Article

An open letter to the BMA and the Academy of Medical Royal Colleges calls on them to make a joint public statement of opposition to the amended section 75 regulations

Children's access to medicines (2012)
Journal Article

Sunday 13 November - Short paper session 2: Children's access to medicines

Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK) (2011)
Journal Article

Background Low levels of physical activity in children have been linked to an increased risk of obesity, but many children lack confidence in relation to exercise (exercise self-efficacy). Factors which can impact on confidence include a chronic hea... Read More about Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK).

Garlic as an inhibitor of pseudomonas aeruginosa quorum sensing in cystic fibrosis - A pilot randomized controlled trial (2010)
Journal Article

Pseudomonas aeruginosa forms biofilms in the cystic fibrosis lung. Quorum sensing (QS) controls biofilm maturation, immune evasion, antibiotic tolerance and virulence factor production. Garlic shows QS inhibitory activity in vitro and in animal model... Read More about Garlic as an inhibitor of pseudomonas aeruginosa quorum sensing in cystic fibrosis - A pilot randomized controlled trial.

Clinical trials: the viewpoint of children with a chronic illness compared with healthy children (2009)
Journal Article

The views of over 200 children (11–16 years old, who were either healthy or attending paediatric medical clinics with a chronic illness) on issues relating to paediatric clinical trials were determined by a questionnaire. Children with a chronic illn... Read More about Clinical trials: the viewpoint of children with a chronic illness compared with healthy children.

Safety in paediatric clinical trials - a 7-year review (2008)
Journal Article

Aim: The safety of clinical trials in children has not been previously studied. We aimed to identify how safety is monitored and the extent of adverse drug reactions (ADRs). Methods: A literature review of the Medline Database for therapeutic clin... Read More about Safety in paediatric clinical trials - a 7-year review.

With Art in Mind (2007)
Journal Article

Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: A population-based cohort study (2007)
Journal Article

There is debate over the mortality and malignancy risk in people with primary biliary cirrhosis (PBC) and whether this risk is reduced by use of ursodeoxycholic acid. To investigate this issue, we identified 930 people with PBC and 9,202 control subj... Read More about Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: A population-based cohort study.

Asthma as a Barrier to Children's Physical Activity: In Reply (2007)
Journal Article