All Outputs (333)

Synovitis and bone marrow lesions associate with symptoms and radiographic progression in hand osteoarthritis: a systematic review and meta-analysis of observational studies (2021)
Journal Article

Aims: To systematically review observational studies for the association between features detected on ultrasound (US) and magnetic resonance imaging (MRI) and, symptoms, signs and radiographic progression of hand osteoarthritis (OA). Methods: Medline... Read More about Synovitis and bone marrow lesions associate with symptoms and radiographic progression in hand osteoarthritis: a systematic review and meta-analysis of observational studies.

Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting (2021)
Journal Article

OBJECTIVE: To determine the burden of comorbidities in OA and their temporal relationships in the UK. METHODS: The Clinical Practice Research Datalink (CPRD) GOLD was used to identify people with incident OA and age, gender and practice matched n... Read More about Temporal relationship between osteoarthritis and comorbidities: a combined case control and cohort study in the UK primary care setting.

Systematic review and meta-analysis of anakinra, sarilumab, siltuximab and tocilizumab for COVID-19 (2021)
Journal Article

Background There is accumulating evidence for an overly activated immune response in severe COVID-19, with several studies exploring the therapeutic role of immunomodulation. Through systematic review and meta-analysis, we assess the effectiveness of... Read More about Systematic review and meta-analysis of anakinra, sarilumab, siltuximab and tocilizumab for COVID-19.

Randomised controlled trial of tailored support to increase physical activity and reduce smoking in smokers not immediately ready to quit: protocol for the Trial of physical Activity-assisted Reduction of Smoking (TARS) Study (2020)
Journal Article

Defining stable glaucoma: a Delphi consensus survey of UK optometrists with a specialist interest in Glaucoma (2020)
Journal Article

Background Increasing demand on hospital services has led to the development of alternative community-based services, often run by optometrists for monitoring ‘stable’ and low-risk glaucoma patients. Methods An online Delphi exercise was underta... Read More about Defining stable glaucoma: a Delphi consensus survey of UK optometrists with a specialist interest in Glaucoma.

Editorial Comment: Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control (2020)
Journal Article

Re: Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case Control Study (2019)
Journal Article

Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review (2019)
Journal Article

Background & aims Weight loss is common in people with neurodegenerative diseases of the motor system (NDMS), such as Parkinson's disease and Amyotrophic Lateral Sclerosis, and is associated with reduced quality of life, functional ability and survi... Read More about Interventions to promote oral nutritional behaviours in people living with neurodegenerative disorders of the motor system: A systematic review.

An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units (2019)
Journal Article

Background Good Clinical Practice guidelines issued in 2016 encourage risk-based approaches to monitoring clinical trials. This study compared current risk assessment and monitoring approaches in UK Clinical Trials Units (CTUs) with the published gu... Read More about An evaluation of risk-based monitoring in pragmatic trials in UK Clinical Trials Units.

ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol (2019)
Journal Article

Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study (2019)
Journal Article

IMPORTANCE Anticholinergic medicines have short-term cognitive adverse effects, but it is uncertain whether long-term use of these drugs is associated with an increased risk of dementia. OBJECTIVE To assess associations between anticholinergic dr... Read More about Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study.

P018 RENAL adverse events and gastrointestinal bleeding with ibuprofen use in preterm neonates with patent ductus arteriosus (PDA) (2019)
Journal Article

Origins of lifetime health around the time of conception: causes and consequences (2018)
Journal Article

Parental environmental factors, including diet, body composition, metabolism, and stress, affect the health and chronic disease risk of people throughout their lives, as captured in the Developmental Origins of Health and Disease concept. Research ac... Read More about Origins of lifetime health around the time of conception: causes and consequences.

368 CFHealthHub: development and evaluation of videos incorporating peer description of successful self-management with inhaled therapies in adults with CF used to build self-efficacy to support self-care within the CFHealthHub complex intervention (2017)
Journal Article

Interventions made by UK pharmacists to minimise risk from paediatric prescribing errors (2016)
Journal Article

The PAndemic INfluenza Triage in the Emergency Department (PAINTED) pilot cohort study (2015)
Journal Article

Background Research needs to be undertaken rapidly in the event of an influenza pandemic to develop and evaluate triage methods for people presenting to the emergency department with suspected pandemic influenza. Objectives We aimed to pilot a r... Read More about The PAndemic INfluenza Triage in the Emergency Department (PAINTED) pilot cohort study.

Maternal Obesity and Infant Mortality: A Meta-Analysis (2014)
Journal Article

BACKGROUND AND OBJECTIVES: Despite numerous studies reporting an elevated risk of infant mortality among women who are obese, the magnitude of the association is unclear. A systematic review and meta-analysis was undertaken to assess the association... Read More about Maternal Obesity and Infant Mortality: A Meta-Analysis.

Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS) (2013)
Journal Article

Background It is good practice for the public to be involved in developing health research. Resources should be available for researchers to fund the involvement of the public in the development of their grants. Objective To describe a funding a... Read More about Supporting public involvement in research design and grant development: a case study of a public involvement award scheme managed by a National Institute for Health Research (NIHR) Research Design Service (RDS).

Act now against new NHS competition regulations (2013)
Journal Article

An open letter to the BMA and the Academy of Medical Royal Colleges calls on them to make a joint public statement of opposition to the amended section 75 regulations

Children's access to medicines (2012)
Journal Article

Sunday 13 November - Short paper session 2: Children's access to medicines