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All Outputs (387)

Oxygen-enhanced MRI assessment of tumour hypoxia in head and neck cancer is feasible and well tolerated in the clinical setting (2024)
Journal Article
McCabe, A., Martin, S., Rowe, S., Shah, J., Morgan, P. S., Borys, D., & Panek, R. (2024). Oxygen-enhanced MRI assessment of tumour hypoxia in head and neck cancer is feasible and well tolerated in the clinical setting. European Radiology Experimental, 8(1), Article 27. https://doi.org/10.1186/s41747-024-00429-1

Background: Tumour hypoxia is a recognised cause of radiotherapy treatment resistance in head and neck squamous cell carcinoma (HNSCC). Current positron emission tomography-based hypoxia imaging techniques are not routinely available in many centres.... Read More about Oxygen-enhanced MRI assessment of tumour hypoxia in head and neck cancer is feasible and well tolerated in the clinical setting.

Allopurinol and blood pressure variability following ischemic stroke and transient ischemic attack: a secondary analysis of XILO-FIST (2024)
Journal Article
MacDonald, A. S., McConnachie, A., Dickie, D. A., Bath, P. M., Forbes, K., Quinn, T., …Dawson, J. (2024). Allopurinol and blood pressure variability following ischemic stroke and transient ischemic attack: a secondary analysis of XILO-FIST. Journal of Human Hypertension, 38, 307-313. https://doi.org/10.1038/s41371-024-00906-5

Blood Pressure Variability (BPV) is associated with cardiovascular risk and serum uric acid level. We investigated whether BPV was lowered by allopurinol and whether it was related to neuroimaging markers of cerebral small vessel disease (CSVD) and c... Read More about Allopurinol and blood pressure variability following ischemic stroke and transient ischemic attack: a secondary analysis of XILO-FIST.

Disclosing non-visible disabilities in educational workplaces: a scoping review (2024)
Journal Article
Hassard, J., Yildrim, M., Thomson, L., & Blake, H. (2024). Disclosing non-visible disabilities in educational workplaces: a scoping review. British Medical Bulletin, 150(1), 23-41. https://doi.org/10.1093/bmb/ldae004

a sizable proportion of the working population has a disability that is not visible. Many choose not to disclose this at work, particularly in educational workplaces where disability is underrepresented. A better understanding of the barriers and fac... Read More about Disclosing non-visible disabilities in educational workplaces: a scoping review.

Group concept mapping to facilitate participatory design of the web-based Pain-at-Work Toolkit (2024)
Presentation / Conference Contribution
Blake, H., Greaves, S., Abbott-Fleming, V., & Somerset, S. (2024, March). Group concept mapping to facilitate participatory design of the web-based Pain-at-Work Toolkit. Presented at 18th International Technology, Education and Development Conference, Valencia, Spain

Concept mapping is increasingly being used as an approach to enhance the development of evidence-based public health interventions. In a prior collaborative-participatory study, Agile methodology was used to co-create the web-based Pain-at-Work (PAW)... Read More about Group concept mapping to facilitate participatory design of the web-based Pain-at-Work Toolkit.

Delivering web-based workforce training interventions: the WWHIDE framework and key considerations for health research (2024)
Presentation / Conference Contribution
Blake, H., Chaplin, W., Hassard, J., & Thomson, L. (2024). Delivering web-based workforce training interventions: the WWHIDE framework and key considerations for health research. In INTED2024 Proceedings: 18th International Technology, Education and Development Conference Valencia, Spain. 4-6 March, 2024. https://doi.org/10.21125/inted.2024.1529

The workplace is an important setting for raising awareness of public health issues and delivering interventions to promote health and wellbeing of working-age adults. The role of employers in supporting the physical and mental health of their employ... Read More about Delivering web-based workforce training interventions: the WWHIDE framework and key considerations for health research.

The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques (2024)
Journal Article
Howell, A. M., Warrington, S., Fonteneau, C., Cho, Y. T., Sotiropoulos, S. N., Murray, J. D., & Anticevic, A. (in press). The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques. eLife, https://doi.org/10.7554/elife.95018.1

Each cortical area has a distinct pattern of anatomical connections within the thalamus, a central subcortical structure composed of functionally and structurally distinct nuclei. Previous studies have suggested that certain cortical areas may have m... Read More about The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques.

Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences (2024)
Journal Article
Patel, P., Brown, S., Guo, B., Holmes, E. A., Iyadurai, L., Kingslake, J., …Morriss, R. (2024). Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences. JMIR Formative Research, 8(1), Article e47458. https://doi.org/10.2196/47458

Background: Many intensive care unit (ICU) staff experience intrusive memories following work-related traumatic events, which can lead to long-term mental health outcomes and impact work functioning. There is a need for interventions that target intr... Read More about Using a Novel Gameplay Intervention to Target Intrusive Memories After Work-Related Trauma: Iterative Qualitative Analysis of Intensive Care Unit Staff Experiences.

Development of a Job Retention Vocational Rehabilitation Intervention for People with Multiple Sclerosis Following the Person-Based Approach (2024)
Journal Article
De Dios Pérez, B., das Nair, R., & Radford, K. (2024). Development of a Job Retention Vocational Rehabilitation Intervention for People with Multiple Sclerosis Following the Person-Based Approach. Clinical Rehabilitation, 38(7), 965-978. https://doi.org/10.1177/02692155241235956

Objective
To describe the process of developing a job retention vocational rehabilitation intervention for people with multiple sclerosis.

Design
We used the person-based approach, to develop interventions through an iterative process incorporat... Read More about Development of a Job Retention Vocational Rehabilitation Intervention for People with Multiple Sclerosis Following the Person-Based Approach.

Influence of Time to Achieve Target Systolic Blood Pressure on Outcome After Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration (2024)
Journal Article
Wang, X., Yang, J., Moullaali, T. J., Sandset, E. C., Woodhouse, L. J., Law, Z. K., Arima, H., Butcher, K. S., Delcourt, C., Mbbs, L. E., Gupta, S., Jiang, W., Koch, S., Potter, J., Qureshi, A. I., Robinson, T. G., Salman, R. A.-S., Saver, J. L., Sprigg, N., Wardlaw, J., …Chalmers, J. (2024). Influence of Time to Achieve Target Systolic Blood Pressure on Outcome After Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration. Stroke, 55(4), 849-855. https://doi.org/10.1161/STROKEAHA.123.044358

OBJECTIVE:
To investigate whether an earlier time to achieving and maintaining systolic blood pressure (SBP) at 120 to 140 mm Hg is associated with favorable outcomes in a cohort of patients with acute intracerebral hemorrhage.

METHODS:
We poole... Read More about Influence of Time to Achieve Target Systolic Blood Pressure on Outcome After Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration.

Influence of Time to Achieve Target Systolic Blood Pressure on Outcome after Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration (2024)
Presentation / Conference Contribution
Wang, X., Yang, J., Moullaali, T. J., Sandset, E. C., Woodhouse, L. J., Law, Z. K., Arima, H., Butcher, K. S., Delcourt, C., Edwards, L., Gupta, S., Jiang, W., Koch, S., Potter, J., Qureshi, A. I., Robinson, T. G., Al-Shahi Salman, R., Saver, J. L., Sprigg, N., Wardlaw, J., …Chalmers, J. (2023, May). Influence of Time to Achieve Target Systolic Blood Pressure on Outcome after Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration. Presented at European Stroke Organisation Conference, Munich

OBJECTIVE:
To investigate whether an earlier time to achieving and maintaining systolic blood pressure (SBP) at 120 to 140 mmHg is associated with favorable outcomes in a cohort of patients with acute intracerebral hemorrhage.

METHODS:
We poo... Read More about Influence of Time to Achieve Target Systolic Blood Pressure on Outcome after Intracerebral Hemorrhage: The Blood Pressure in Acute Stroke Collaboration.

Using Electronic Health Records to Facilitate Precision Psychiatry (2024)
Journal Article
Oliver, D., Arribas, M., Perry, B. I., Whiting, D., Blackman, G., Krakowski, K., Seyedsalehi, A., Osimo, E. F., Griffiths, S. L., Stahl, D., Cipriani, A., Fazel, S., Fusar-Poli, P., & McGuire, P. (2024). Using Electronic Health Records to Facilitate Precision Psychiatry. Biological Psychiatry, 96(7), 532-542. https://doi.org/10.1016/j.biopsych.2024.02.1006

The use of clinical prediction models to produce individualized risk estimates can facilitate the implementation of precision psychiatry. As a source of data from large, clinically representative patient samples, electronic health records (EHRs) prov... Read More about Using Electronic Health Records to Facilitate Precision Psychiatry.

Generalising XTRACT tractography protocols across common macaque brain templates (2024)
Journal Article
Assimopoulos, S., Warrington, S., Bryant, K. L., Pszczolkowski, S., Jbabdi, S., Mars, R. B., & Sotiropoulos, S. N. (2024). Generalising XTRACT tractography protocols across common macaque brain templates. Brain Structure and Function, https://doi.org/10.1007/s00429-024-02760-0

Non-human primates are extensively used in neuroscience research as models of the human brain, with the rhesus macaque being a prominent example. We have previously introduced a set of tractography protocols (XTRACT) for reconstructing 42 correspondi... Read More about Generalising XTRACT tractography protocols across common macaque brain templates.

On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations (2024)
Journal Article
Helmer, M., Warrington, S., Mohammadi-Nejad, A., Ji, J. L., Howell, A., Rosand, B., …Murray, J. D. (2024). On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations. Communications Biology, 7(1), Article 217. https://doi.org/10.1038/s42003-024-05869-4

Associations between datasets can be discovered through multivariate methods like Canonical Correlation Analysis (CCA) or Partial Least Squares (PLS). A requisite property for interpretability and generalizability of CCA/PLS associations is stability... Read More about On the stability of canonical correlation analysis and partial least squares with application to brain-behavior associations.

Muddy, muddled, or muffled? Understanding the perception of audio quality in music by hearing aid users (2024)
Journal Article
Bannister, S., Greasley, A. E., Cox, T. J., Akeroyd, M. A., Barker, J., Fazenda, B., …Whitmer, W. M. (2024). Muddy, muddled, or muffled? Understanding the perception of audio quality in music by hearing aid users. Frontiers in Psychology, 15, https://doi.org/10.3389/fpsyg.2024.1310176

Introduction: Previous work on audio quality evaluation has demonstrated a developing convergence of the key perceptual attributes underlying judgments of quality, such as timbral, spatial and technical attributes. However, across existing research t... Read More about Muddy, muddled, or muffled? Understanding the perception of audio quality in music by hearing aid users.

Approaches and challenges to assessing risk of violence in first episode psychosis: A qualitative interview study of clinicians, patients and carers (2024)
Journal Article
Whiting, D., Glogowska, M., Fazel, S., & Lennox, B. (2024). Approaches and challenges to assessing risk of violence in first episode psychosis: A qualitative interview study of clinicians, patients and carers. Early Intervention in Psychiatry, 18(8), 624-632. https://doi.org/10.1111/eip.13502

Aim: Clinical services for early psychosis seek to improve prognosis for a range of adverse outcomes. For some individuals, perpetration of violence is an important potential outcome to reduce. How these clinical services currently assess this risk h... Read More about Approaches and challenges to assessing risk of violence in first episode psychosis: A qualitative interview study of clinicians, patients and carers.

Top ten research priorities for alcohol use disorder and alcohol-related liver disease: results of a multistakeholder research priority setting partnership (2024)
Journal Article
Subhani, M., Dhanda, A., Olaru, A., Dunford, L., Ahmad, N., Wragg, A., Frost, K., Greenwood, J., King, M., Jones, K. A., Rosenberg, W., Sinclair, J., Rennick-Egglestone, S., Morling, J. R., Patel, K., & Ryder, S. D. (2024). Top ten research priorities for alcohol use disorder and alcohol-related liver disease: results of a multistakeholder research priority setting partnership. The Lancet Gastroenterology & Hepatology, 9(5), 400-402. https://doi.org/10.1016/S2468-1253%2824%2900009-8

Alcohol is a preventable leading cause of liver disease and over 200 other acute or chronic medical conditions. 1 In the UK, 25% of the population drinks at an increasing risk level (ie, 15–34 units per week for women and 15–49 units per week for men... Read More about Top ten research priorities for alcohol use disorder and alcohol-related liver disease: results of a multistakeholder research priority setting partnership.

Associations of physical activity and cardiorespiratory fitness with cognitive function, self-control, and resilience in young people with attention deficit hyperactivity disorder (2024)
Journal Article
Sibbick, E., Boat, R., Sarkar, M., Johnston, J. P., Groom, M., Williams, R. A., …Cooper, S. B. (2024). Associations of physical activity and cardiorespiratory fitness with cognitive function, self-control, and resilience in young people with attention deficit hyperactivity disorder. Advanced Exercise and Health Science, 1(1), 51-58. https://doi.org/10.1016/j.aehs.2024.01.003

The aim of the present study was to investigate if physical activity and cardiorespiratory fitness influence cognition, self-control, and resilience in young people with ADHD. Fifty-four children with ADHD (12.8 ± 1.4 y) completed questionnaires to a... Read More about Associations of physical activity and cardiorespiratory fitness with cognitive function, self-control, and resilience in young people with attention deficit hyperactivity disorder.

Implementing internet-based cognitive behavioural therapy (moodgym) for African students with symptoms of low mood during the COVID-19 pandemic: a qualitative feasibilty study (2024)
Journal Article
Ncheka, J. M., Menon, J. A., Davies, E. B., Paul, R., Mwaba, S. O. C., Mudenda, J., Wharrad, H., Tak, H., & Glazebrook, C. (2024). Implementing internet-based cognitive behavioural therapy (moodgym) for African students with symptoms of low mood during the COVID-19 pandemic: a qualitative feasibilty study. BMC Psychiatry, 24(1), Article 92. https://doi.org/10.1186/s12888-024-05542-4

Background: Online therapies have been shown to be effective in improving students’ mental health. They are cost-effective and therefore have particular advantages in low-income countries like Zambia where mental health resources are limited. This st... Read More about Implementing internet-based cognitive behavioural therapy (moodgym) for African students with symptoms of low mood during the COVID-19 pandemic: a qualitative feasibilty study.

Experiences and impact of psychiatric inpatient admissions far away from home: a qualitative study with young people, parents/carers and healthcare professionals (2024)
Journal Article
Roe, J., Holland, J., Burn, A., Hopkin, E., Wild, L., Fisher, M., …Sayal, K. (2024). Experiences and impact of psychiatric inpatient admissions far away from home: a qualitative study with young people, parents/carers and healthcare professionals. BMJ Mental Health, 27(1), Article e300991. https://doi.org/10.1136/bmjment-2024-300991

Background: There are significant clinical, policy and societal concerns about the impact on young people (YP), from admission to psychiatric wards far from home. However, research evidence is scarce.
Aims: To investigate the impact of at-distance... Read More about Experiences and impact of psychiatric inpatient admissions far away from home: a qualitative study with young people, parents/carers and healthcare professionals.