All Outputs (2)

Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial (2017)
Journal Article
Lindsay, J. O., Clark, M., Allez, M., Labopin, M., Rogler, G., Rovira, M., …Ricart, E. (2017). Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial. Lancet Gastroenterology and Hepatology, 2(6), 399-406. https://doi.org/10.1016/S2468-1253%2817%2930056-0

Background: The randomised controlled ASTIC trial showed no benefit of mobilisation and autologous haematopoietic stem-cell transplantation (HSCT) compared with mobilisation followed by conventional therapy using a stringent primary endpoint (steroid... Read More about Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial.

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial (2015)
Journal Article
Hawkey, C. J., Allez, M., Clark, M. M., Labopin, M., Lindsay, J. O., Ricart, E., …Farge, D. (2015). Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial. Journal of the American Medical Association, 314(23), 2524-2534. https://doi.org/10.1001/jama.2015.16700

Importance: Case reports and series suggest hematopoietic stem cell transplantation (HSCT) may benefit some patients with Crohn disease. Objective: To evaluate the effect of autologous HSCT on refractory Crohn disease. Design, Setting, and Pa... Read More about Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.