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Vitamin D - a new treatment for airway remodelling in asthma? (2009)
Journal Article
Clifford, R. L., & Knox, A. J. (2009). Vitamin D - a new treatment for airway remodelling in asthma?. British Journal of Pharmacology, 158(6), 1426-1428. https://doi.org/10.1111/j.1476-5381.2009.00429.x

Increased airway smooth muscle (ASM) mass plays a critical role in chronic asthmatic airway remodelling. ASM cell hypertrophy and hyperplasia are likely to contribute to increased ASM mass and a variety of mitogens induce ASM proliferation in cell cu... Read More about Vitamin D - a new treatment for airway remodelling in asthma?.

Novel Regulation of Vascular Endothelial Growth Factor-A (VEGF-A) by Transforming Growth Factor ?1: REQUIREMENT FOR Smads,?-CATENIN, AND GSK3? (2008)
Journal Article
Clifford, R. L., Deacon, K., & Knox, A. J. (2008). Novel Regulation of Vascular Endothelial Growth Factor-A (VEGF-A) by Transforming Growth Factor ?1: REQUIREMENT FOR Smads,?-CATENIN, AND GSK3?. Journal of Biological Chemistry, 283(51), 35337-35353. https://doi.org/10.1074/jbc.m803342200

Vascular endothelial growth factor (VEGF) is a vital angiogenic effector, regulating key angiogenic processes. Vascular development relies on numerous signaling pathways, of which those induced by transforming growth factor-? (TGF?) are critical. The... Read More about Novel Regulation of Vascular Endothelial Growth Factor-A (VEGF-A) by Transforming Growth Factor ?1: REQUIREMENT FOR Smads,?-CATENIN, AND GSK3?.

Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP 2/EP4 receptors and SP-1 transcription factor binding sites (2005)
Journal Article
Bradbury, D., Clarke, D., Seedhouse, C., Corbettt, L., Stocks, J., & Knox, A. (2005). Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP 2/EP4 receptors and SP-1 transcription factor binding sites. Journal of Biological Chemistry, 280(34), 29993-30000. https://doi.org/10.1074/jbc.M414530200

Prostaglandin E2 (PGE2) can increase vascular endothelial growth factor A (VEGF-A) production but the mechanisms involved are unclear. Here we characterized the transcriptional mechanisms involved in human airway smooth muscle cells (HASMC). PGE2 inc... Read More about Vascular endothelial growth factor induction by prostaglandin E2 in human airway smooth muscle cells is mediated by E prostanoid EP 2/EP4 receptors and SP-1 transcription factor binding sites.