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All Outputs (559)

Effects on abstinence of nicotine patch treatment prior to quitting smoking: a parallel, two-arm, pragmatic randomised trial (2018)
Journal Article

Objectives: Standard smoking cessation pharmacotherapy is recommended in the post-quit period, but may also facilitate abstinence if used prior to quitting. The objective was to examine the effectiveness and cost-effectiveness of nicotine patch worn... Read More about Effects on abstinence of nicotine patch treatment prior to quitting smoking: a parallel, two-arm, pragmatic randomised trial.

Developing a measure of polypharmacy appropriateness in primary care: systematic review and expert consensus study (2018)
Journal Article

Background: Polypharmacy is an increasing challenge for primary care. Although sometimes clinically justified, polypharmacy can be inappropriate, leading to undesirable outcomes. Optimising care for polypharmacy necessitates effective targeting and m... Read More about Developing a measure of polypharmacy appropriateness in primary care: systematic review and expert consensus study.

Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study (2018)
Journal Article

Objective: To quantify psychological morbidity and identify baseline factors associated with depression, anxiety and post-traumatic distress symptoms up to 12 months post-injury. Methods: Multicentre cohort study of 668 adults, aged 16 to 70,... Read More about Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study.

Informing evaluation of a smartphone application for people with acquired brain injury: a stakeholder engagement study (2018)
Journal Article

Background Brain in Hand is a smartphone application (app) that allows users to create structured diaries with problems and solutions, attach reminders, record task completion and has a symptom monitoring system. Brain in Hand was designed to supp... Read More about Informing evaluation of a smartphone application for people with acquired brain injury: a stakeholder engagement study.

Intervention planning for the REDUCE maintenance intervention: a digital intervention to reduce re-ulceration risk among patients with a history of diabetic foot ulcers (2018)
Journal Article

Objectives: To develop a comprehensive intervention plan for the REDUCE maintenance intervention to support people who have had diabetic foot ulcers (DFUs) to sustain behaviours that reduce re-ulceration risk. Methods: Theory-, evidence- and perso... Read More about Intervention planning for the REDUCE maintenance intervention: a digital intervention to reduce re-ulceration risk among patients with a history of diabetic foot ulcers.

Cost-utility analysis of searching electronic health records and cascade testing to identify and diagnose familial hypercholesterolaemia in England and Wales (2018)
Journal Article

Background and aims: The cost effectiveness of cascade testing for familial hypercholesterolaemia (FH) is well recognised. Less clear is the cost effectiveness of FH screening when it includes case identification strategies that incorporate routinely... Read More about Cost-utility analysis of searching electronic health records and cascade testing to identify and diagnose familial hypercholesterolaemia in England and Wales.

Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial (2018)
Journal Article

Background: Antenatal depression is associated with harmful consequences for both the mother and child. One intervention that might be effective is participation in regular physical activity although data on this question in pregnant smokers is curre... Read More about Physical activity for antenatal and postnatal depression in women attempting to quit smoking: randomised controlled trial.

Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study (2018)
Journal Article

Background and Aims: Familial hypercholesterolaemia (FH) is a major cause of premature heart disease but remains unrecognised in most patients. This study investigated if a systematic primary care-based approach to identify and manage possible FH imp... Read More about Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study.

Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study (2018)
Journal Article

Background: Smoking in pregnancy is a major public health concern. Pregnant smokers are particularly difficult to reach, with low uptake of support options and few effective interventions. Text message–based self-help is a promising, low-cost interve... Read More about Uptake of Tailored Text Message Smoking Cessation Support in Pregnancy When Advertised on the Internet (MiQuit): Observational Study.

Does bone mineral density improve the predictive accuracy of fracture risk assessment?: a prospective cohort study in Northern Denmark (2018)
Journal Article

Objective: To evaluate the added predictive accuracy of bone mineral density (BMD) to fracture risk assessment.Design Prospective cohort study using data between 01 January 2010 and 31 December 2012. Setting: North Denmark Osteoporosis Clinic of r... Read More about Does bone mineral density improve the predictive accuracy of fracture risk assessment?: a prospective cohort study in Northern Denmark.

Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database (2018)
Journal Article

© 2018 The Author(s). Background: Antidepressants are one of the most commonly prescribed medications in young and middle-aged adults, but there is relatively little information on their safety across a range of adverse outcomes in this age group. Th... Read More about Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database.

Improving behavioral support for smoking cessation in pregnancy: what are the barriers to stopping and which behavior change techniques can influence these?: application of theoretical domains framework (2018)
Journal Article

Behavioral support interventions are used to help pregnant smokers stop; however, of those tested, few are proven effective. Systematic research developing effective pregnancy-specific behavior change techniques (BCTs) is ongoing. This paper reports... Read More about Improving behavioral support for smoking cessation in pregnancy: what are the barriers to stopping and which behavior change techniques can influence these?: application of theoretical domains framework.

A development study and randomised feasibility trial of a tailored intervention to improve activity and reduce falls in older adults with mild cognitive impairment and mild dementia (2018)
Journal Article

Background: People with dementia progressively lose abilities and are prone to falling. Exercise- and activity-based interventions hold the prospect of increasing abilities, reducing falls, and slowing decline in cognition. Current falls prevention... Read More about A development study and randomised feasibility trial of a tailored intervention to improve activity and reduce falls in older adults with mild cognitive impairment and mild dementia.