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All Outputs (5)

Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care (2018)
Journal Article
Vinogradova, Y., Coupland, C., Hill, T., & Hippisley-Cox, J. (2018). Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care. BMJ, 362, Article k2505. https://doi.org/10.1136/bmj.k2505

Objective: To investigate the associations between direct oral anticoagulants (DOACs) and risks of bleeding, ischaemic stroke, venous thromboembolism, and all cause mortality compared with warfarin. Design: Prospective open cohort study. Settin... Read More about Risks and benefits of direct oral anticoagulants versus warfarin in a real world setting: cohort study in primary care.

Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study (2018)
Journal Article
Kendrick, D., Baker, R., Hill, T., Beckett, K., Coupland, C., Kellezi, B., …Morriss, R. (2018). Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study. Journal of Psychosomatic Research, 112, 15-24. https://doi.org/10.1016/j.jpsychores.2018.06.008

Objective: To quantify psychological morbidity and identify baseline factors associated with depression, anxiety and post-traumatic distress symptoms up to 12 months post-injury. Methods: Multicentre cohort study of 668 adults, aged 16 to 70,... Read More about Early risk factors for depression, anxiety and post-traumatic distress after hospital admission for unintentional injury: multicentre cohort study.

Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database (2018)
Journal Article
Coupland, C., Hill, T., Morriss, R., Moore, M., Arthur, A., & Hippisley-Cox, J. (2018). Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database. BMC Medicine, 16(1), Article 36. https://doi.org/10.1186/s12916-018-1022-x

© 2018 The Author(s). Background: Antidepressants are one of the most commonly prescribed medications in young and middle-aged adults, but there is relatively little information on their safety across a range of adverse outcomes in this age group. Th... Read More about Antidepressant use and risk of adverse outcomes in people aged 20–64 years: cohort study using a primary care database.

PHysical activity Implementation Study In Community-dwelling AduLts (PHISICAL): study protocol (2018)
Journal Article
Carpenter, H., Audsley, S., Coupland, C., Gladman, J. R., Kendrick, D., Lafond, N., …Orton, E. (in press). PHysical activity Implementation Study In Community-dwelling AduLts (PHISICAL): study protocol. Injury Prevention, https://doi.org/10.1136/injuryprev-2017-042627

Background: Falls in older people are a leading causes of unintentional injury. Due to an ageing population, injuries are likely to increase unless more is done to reduce older people’s falls risk. In clinical trials, the Falls Management Exercise (F... Read More about PHysical activity Implementation Study In Community-dwelling AduLts (PHISICAL): study protocol.