All Outputs (2)

Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition (2015)
Journal Article
Ledaki, I., MCINTYRE, A., Wigfield, S., Buffa, F., McGowan, S., Baban, D., …Harris, A. L. (2015). Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. Oncotarget, 6(23), 19413-19427. https://doi.org/10.18632/oncotarget.4989

The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions (2015)
Journal Article
Tapmeier, T. T., Moshnikova, A., Beech, J., Allen, D., Kinchesh, P., Smart, S., …Muschel, R. J. (2015). The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions. Proceedings of the National Academy of Sciences, 112(31), 9710-9715. https://doi.org/10.1073/pnas.1509488112

Current strategies for early detection of breast and other cancers are limited in part because some lesions identified as potentially malignant do not develop into aggressive tumors. Acid pH has been suggested as a key characteristic of aggressive tu... Read More about The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions.