All Outputs (2)

Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I. (2014)
Journal Article
Watson, H. A., Holley, R. J., Langford-Smith, K. J., Wilkinson, F. L., van Kuppevelt, T. H., Wynn, R. F., …Bigger, B. W. (2014). Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I. Journal of Biological Chemistry, 289(52), 36194-36203. https://doi.org/10.1074/jbc.M114.599944

Mucopolysaccharidosis I Hurler (MPSI-H) is a pediatric lysosomal storage disease caused by genetic deficiencies in IDUA, coding for ?-l-iduronidase. Idua?/? mice share similar clinical pathology with patients, including the accumulation of the undegr... Read More about Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I..

Novel cell lines isolated from mouse embryonic stem cells exhibiting de novo methylation of the E-cadherin promoter. (2014)
Journal Article
Hawkins, K., Keramari, M., Soncin, F., Segal, J. M., Mohamet, L., Miazga, N., …Ward, C. M. (2014). Novel cell lines isolated from mouse embryonic stem cells exhibiting de novo methylation of the E-cadherin promoter. STEM CELLS, 32(11), 2869-2879. https://doi.org/10.1002/stem.1790

Mouse embryonic stem cells (mESCs) and epiblast stem cells represent the naïve and primed pluripotent states, respectively. These cells self‐renew via distinct signaling pathways and can transition between the two states in the presence of appropriat... Read More about Novel cell lines isolated from mouse embryonic stem cells exhibiting de novo methylation of the E-cadherin promoter..