All Outputs (1122)

Operculo-Insular and Anterior Cingulate Plasticity Induced by Transcranial Magnetic Stimulation in the Human Motor Cortex: A Dynamic Casual Modelling Study (2021)
Journal Article

The ability to induce neuroplasticity with non-invasive brain stimulation techniques offers a unique opportunity to examine the human brain systems involved in pain modulation. In experimental and clinical settings, the primary motor cortex (M1) is c... Read More about Operculo-Insular and Anterior Cingulate Plasticity Induced by Transcranial Magnetic Stimulation in the Human Motor Cortex: A Dynamic Casual Modelling Study.

Outcomes in Antiplatelet?Associated Intracerebral Hemorrhage in the TICH?2 Randomized Controlled Trial (2021)
Journal Article

Background Antiplatelet therapy increases the risk of hematoma expansion in intracerebral hemorrhage (ICH) while the effect on functional outcome is uncertain. Methods and Results This is an exploratory analysis of the TICH‐2 (Tranexamic Acid in... Read More about Outcomes in Antiplatelet?Associated Intracerebral Hemorrhage in the TICH?2 Randomized Controlled Trial.

Salicylate decreases the spontaneous firing rate of guinea pig auditory nerve fibres (2021)
Journal Article

Tinnitus has similarities to chronic neuropathic pain where there are changes in the firing rate of different types of afferent neurons. We postulated that one possible cause of tinnitus is a change in the distribution of spontaneous firing rates in... Read More about Salicylate decreases the spontaneous firing rate of guinea pig auditory nerve fibres.

Effect of variable pre-oxygenation endpoints on safe apnoea time using high flow nasal oxygen for women in labour: a modelling investigation (2021)
Journal Article

Background Studies of pulmonary denitrogenation (pre-oxygenation) in obstetric populations have shown high flow nasal oxygen therapy (HFNO) is inferior to facemask techniques. HFNO achieves median end-tidal oxygen fraction (FE′O2) of 0.87 after 3... Read More about Effect of variable pre-oxygenation endpoints on safe apnoea time using high flow nasal oxygen for women in labour: a modelling investigation.

Tinnitus and Tinnitus Disorder: Theoretical and Operational Definitions (An international multidisciplinary proposal) (2021)
Book Chapter

As for hypertension, chronic pain, epilepsy and other disorders with particular symptoms, a commonly accepted and unambiguous definition provides a common ground for researchers and clinicians to study and treat the problem. The WHO's ICD11 definitio... Read More about Tinnitus and Tinnitus Disorder: Theoretical and Operational Definitions (An international multidisciplinary proposal).

Hearing Aids Reduce Daily-Life Fatigue and Increase Social Activity: A Longitudinal Study (2021)
Journal Article

People with hearing loss experience fatigue, and it is unknown whether this is alleviated by treatment with hearing aids. The objective of this study was to address this issue and to investigate the possible concomitant effect of hearing-aid fitting... Read More about Hearing Aids Reduce Daily-Life Fatigue and Increase Social Activity: A Longitudinal Study.

The prevalence of tinnitus in China: a systematic review of the literature (2021)
Journal Article

Purpose: The aim of the present study was to identify reports of the prevalence of tinnitus in China and to present these findings in a review format. Method: We assessed and collated published prevalence estimates of tinnitus and tinnitus severity,... Read More about The prevalence of tinnitus in China: a systematic review of the literature.

Age-related normative changes in cerebral perfusion: data from The Irish Longitudinal Study on Ageing (TILDA) (2021)
Journal Article

Objective To establish normative reference values for total grey matter cerebral blood flow (CBFGM) measured using pseudo-continuous arterial spin labelling (pCASL) MRI in a large cohort of community-dwelling adults aged 54 years and older. Backgroun... Read More about Age-related normative changes in cerebral perfusion: data from The Irish Longitudinal Study on Ageing (TILDA).

Multimodal imaging brain markers in early adolescence are linked with a physically active lifestyle (2021)
Journal Article

© 2021 Salvan et al. The World Health Organization promotes physical exercise and a healthy lifestyle as means to improve youth development. However, relationships between physical lifestyle and human brain development are not fully understood. Here,... Read More about Multimodal imaging brain markers in early adolescence are linked with a physically active lifestyle.

Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance (2021)
Journal Article

Corneal opacity is the 5th leading cause of blindness and visual impairment globally, affecting ~6 million of the world population. In addition, it is responsible for 1.5–2.0 million new cases of monocular blindness per year, highlighting an ongoing... Read More about Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance.

Pilot Randomised Evaluation of Singing in Dementia (PRESIDE): protocol for a two-arm, parallel group randomised controlled feasibility study with waiting-list control (2021)
Journal Article

Background As the number of people living with dementia grows, so does the need to provide them with adequate psychosocial support. Many people with dementia live at home with family carers, who also require social and emotional support to cope wi... Read More about Pilot Randomised Evaluation of Singing in Dementia (PRESIDE): protocol for a two-arm, parallel group randomised controlled feasibility study with waiting-list control.

The secretome of endothelial progenitor cells: a potential therapeutic strategy for ischemic stroke (2021)
Journal Article

Ischemic stroke continues to be a leading cause of mortality and morbidity in the world. Despite recent advances in the field of stroke medicine, thrombolysis with recombinant tissue plasminogen activator remains as the only pharmacological therapy f... Read More about The secretome of endothelial progenitor cells: a potential therapeutic strategy for ischemic stroke.

Morbidity and Complications of Diabetes Mellitus in Children and Adolescents in Ghana: Protocol for a longitudinal study (2021)
Journal Article

Quantum computing at the frontiers of biological sciences (2021)
Journal Article

The search for meaningful structure in biological data has relied on cutting-edge advances in computational technology and data science methods. However, challenges arise as we push the limits of scale and complexity in biological problems. Innovatio... Read More about Quantum computing at the frontiers of biological sciences.

Can listening-related fatigue influence well-being? Examining associations between hearing loss, fatigue, activity levels and well-being (2021)
Journal Article

Objective Well-being is influenced by the activities we undertake. Hearing loss may reduce well-being directly through increased listening-related fatigue due to cognitive and emotional strain in challenging situations. Hearing loss and hearing devi... Read More about Can listening-related fatigue influence well-being? Examining associations between hearing loss, fatigue, activity levels and well-being.

Associations Between Hearing and Cognitive Abilities From Childhood to Middle Age: The National Child Development Study 1958 (2021)
Journal Article

Previous cross-sectional findings indicate that hearing and cognitive abilities are positively correlated in childhood, adulthood, and older age. We used an unusually valuable longitudinal dataset from a single-year birth cohort study, the National C... Read More about Associations Between Hearing and Cognitive Abilities From Childhood to Middle Age: The National Child Development Study 1958.

Neural Fields with Rebound Currents: Novel Routes to Patterning (2021)
Journal Article

The understanding of how spatio-temporal patterns of neural activity may arise in the cortex of the brain has advanced with the development and analysis of neural field models. To replicate this success for sub-cortical tissues, such as the thalamus,... Read More about Neural Fields with Rebound Currents: Novel Routes to Patterning.

Modelling white matter in gyral blades as a continuous vector field (2020)
Journal Article

© 2020 Many brain imaging studies aim to measure structural connectivity with diffusion tractography. However, biases in tractography data, particularly near the boundary between white matter and cortical grey matter can limit the accuracy of such st... Read More about Modelling white matter in gyral blades as a continuous vector field.

MicroRNA: An Emerging Predictive, Diagnostic, Prognostic and Therapeutic Strategy in Ischaemic Stroke (2020)
Journal Article

Stroke continues to be the third-leading cause of death and disability worldwide. The limited availability of diagnostic tools approved therapeutics and biomarkers that help monitor disease progression or predict future events remain as the major cha... Read More about MicroRNA: An Emerging Predictive, Diagnostic, Prognostic and Therapeutic Strategy in Ischaemic Stroke.

Prognostication and contemporary management of clinically isolated syndrome (2020)
Journal Article

Clinically isolated syndrome (CIS) patients present with a single attack of inflammatory demyelination of the central nervous system. Recent advances in multiple sclerosis (MS) diagnostic criteria have expanded the number of CIS patients eligible for... Read More about Prognostication and contemporary management of clinically isolated syndrome.