All Outputs (129)

The Pain at Work Toolkit for Employees with Chronic or Persistent Pain: A Collaborative-Participatory Study (2021)
Journal Article
Blake, H., Somerset, S., & Greaves, S. (2022). The Pain at Work Toolkit for Employees with Chronic or Persistent Pain: A Collaborative-Participatory Study. Healthcare, 10(1), Article 56. https://doi.org/10.3390/healthcare10010056

Self-management tools for people with chronic or persistent pain tend to focus on symptom reporting, treatment programmes or exercise and do not address barriers to work, facilitators of work ability, or workplace pain self-management strategies. We... Read More about The Pain at Work Toolkit for Employees with Chronic or Persistent Pain: A Collaborative-Participatory Study.

Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function (2021)
Journal Article
Singh, S., Almuhanna, Y., Alshahrani, M. Y., Lowman, D. W., Rice, P. J., Gell, C., …Martinez-Pomares, L. (2021). Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function. npj Biofilms and Microbiomes, 7(1), Article 87. https://doi.org/10.1038/s41522-021-00257-w

Bacterial biofilms represent a challenge to the healthcare system because of their resilience against antimicrobials and immune attack. Biofilms consist of bacterial aggregates embedded in an extracellular polymeric substance (EPS) composed of polysa... Read More about Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function.

Impact of mass vaccination on SARS-CoV-2 infections among multiple sclerosis patients taking immunomodulatory disease-modifying therapies in England (2021)
Journal Article
Garjani, A., Patel, S., Bharkhada, D., Rashid, W., Coles, A., Law, G. R., & Evangelou, N. (2022). Impact of mass vaccination on SARS-CoV-2 infections among multiple sclerosis patients taking immunomodulatory disease-modifying therapies in England. Multiple Sclerosis and Related Disorders, 57, Article 103458. https://doi.org/10.1016/j.msard.2021.103458

Background: Contradicting assumptions have been made about the effectiveness of SARS-CoV-2 vaccines in patients with multiple sclerosis (MS) receiving immunomodulatory disease-modifying therapies (DMTs) based on the quantification of humoral and cell... Read More about Impact of mass vaccination on SARS-CoV-2 infections among multiple sclerosis patients taking immunomodulatory disease-modifying therapies in England.

Intra-tracheal multiplexed sensing of contact pressure and perfusion (2021)
Journal Article
Correia, R., Gadsby, B., Korposh, S., Norris, A. M., Hayes-Gill, B. R., Sinha, R., …Morgan, S. P. (2022). Intra-tracheal multiplexed sensing of contact pressure and perfusion. Biomedical Optics Express, 13(1), 48-64. https://doi.org/10.1364/BOE.442165

Incorrect endotracheal tube (ETT) cuff inflation pressure causes significant problems for intubated patients. The technical development and first in vivo use of a smart ETT for measurements at the cuff-trachea interface during mechanical ventilation... Read More about Intra-tracheal multiplexed sensing of contact pressure and perfusion.

Pre-hospital continuous positive airway pressure after blast lung injury and hypovolaemic shock: a modelling study (2021)
Journal Article
Mistry, S., Das, A., Hardman, J. G., Bates, D. G., & Scott, T. E. (2022). Pre-hospital continuous positive airway pressure after blast lung injury and hypovolaemic shock: a modelling study. British Journal of Anaesthesia, 128(2), e151-e157. https://doi.org/10.1016/j.bja.2021.10.012

Background In non-traumatic respiratory failure, pre-hospital application of CPAP reduces the need for intubation. Primary blast lung injury (PBLI) accompanied by haemorrhagic shock is common after mass casualty incidents. We hypothesised that pre-h... Read More about Pre-hospital continuous positive airway pressure after blast lung injury and hypovolaemic shock: a modelling study.

Sensorineural Hearing Loss (2021)
Book Chapter
Cheung, L., Baguley, D., & McCombe, A. (2021). Sensorineural Hearing Loss. In R. A. England, & E. Shamil (Eds.), Scott-Brown's Essential Otorhinolaryngology, Head & Neck Surgery. CRC Press

Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial (2021)
Journal Article
the TICH-2 Investigators, Law, Z. K., Appleton, J. P., Scutt, P., Roberts, I., Al-Shahi Salman, R., …Sprigg, N. (2021). Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial. Stroke, 53(4), 1141-1148. https://doi.org/10.1161/STROKEAHA.121.035191

Background: Seeking consent rapidly in acute stroke trials is crucial as interventions are time sensitive. We explored the association between consent pathways and time to enrollment in the TICH-2 (Tranexamic Acid in Intracerebral Haemorrhage-2) rand... Read More about Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial.

Recovery From COVID-19 in Multiple Sclerosis: A Prospective and Longitudinal Cohort Study of the United Kingdom Multiple Sclerosis Register (2021)
Journal Article
Garjani, A., Middleton, R. M., Nicholas, R., & Evangelou, N. (2022). Recovery From COVID-19 in Multiple Sclerosis: A Prospective and Longitudinal Cohort Study of the United Kingdom Multiple Sclerosis Register. Neurology, Neuroimmunology and Neuroinflammation, 9(1), Article e1118. https://doi.org/10.1212/nxi.0000000000001118

Background and Objectives: To understand the course of recovery from coronavirus disease 2019 (COVID-19) among patients with multiple sclerosis (MS) and to determine its predictors, including patients' pre–COVID-19 physical and mental health status.... Read More about Recovery From COVID-19 in Multiple Sclerosis: A Prospective and Longitudinal Cohort Study of the United Kingdom Multiple Sclerosis Register.

Meta-Analysis of Apparent Diffusion Coefficient in Pediatric Medulloblastoma, Ependymoma, and Pilocytic Astrocytoma (2021)
Journal Article
Dury, R. J., Lourdusamy, A., Macarthur, D. C., Peet, A. C., Auer, D. P., Grundy, R. G., & Dineen, R. A. (2022). Meta-Analysis of Apparent Diffusion Coefficient in Pediatric Medulloblastoma, Ependymoma, and Pilocytic Astrocytoma. Journal of Magnetic Resonance Imaging, 56(1), 147-157. https://doi.org/10.1002/jmri.28007

Background: Medulloblastoma, ependymoma, and pilocytic astrocytoma are common pediatric posterior fossa tumors. These tumors show overlapping characteristics on conventional MRI scans, making diagnosis difficult. Purpose: To investigate whether appar... Read More about Meta-Analysis of Apparent Diffusion Coefficient in Pediatric Medulloblastoma, Ependymoma, and Pilocytic Astrocytoma.

Midfrontal theta oscillations and conflict monitoring in children and adults (2021)
Journal Article
Chevalier, N., Hadley, L. V., & Balthrop, K. (2021). Midfrontal theta oscillations and conflict monitoring in children and adults. Developmental Psychobiology, 63(8), Article e22216. https://doi.org/10.1002/dev.22216

Conflict monitoring is central in cognitive control, as detection of conflict serves as a signal for the need to engage control. This study examined whether (1) midfrontal theta oscillations similarly support conflict monitoring in children and adult... Read More about Midfrontal theta oscillations and conflict monitoring in children and adults.

Sound pressure levels in close proximity to sound reinforcement loudspeakers (2021)
Conference Proceeding
Wiggins, I., & Liston, K. (2021). Sound pressure levels in close proximity to sound reinforcement loudspeakers. In Proceedings of the Institute of Acoustics. https://doi.org/10.25144/13800

Clinical Characteristics and Outcomes of Fungal Keratitis in the United Kingdom 2011–2020: A 10-Year Study (2021)
Journal Article
Ting, D. S. J., Galal, M., Kulkarni, B., Elalfy, M. S., Lake, D., Hamada, S., …Dua, H. S. (2021). Clinical Characteristics and Outcomes of Fungal Keratitis in the United Kingdom 2011–2020: A 10-Year Study. Journal of Fungi, 7(11), Article 966. https://doi.org/10.3390/jof7110966

Fungal keratitis (FK) is a serious ocular infection that often poses significant diagnostic and therapeutic dilemmas. This study aimed to examine the causes, clinical characteristics, out-comes, and prognostic factors of FK in the UK. All culture-pos... Read More about Clinical Characteristics and Outcomes of Fungal Keratitis in the United Kingdom 2011–2020: A 10-Year Study.

The effect of stimulus duration on preferences for gain adjustments when listening to speech (2021)
Journal Article
Whitmer, W. M., Caswell-Midwinter, B., & Naylor, G. (2022). The effect of stimulus duration on preferences for gain adjustments when listening to speech. International Journal of Audiology, 61(11), 940-947. https://doi.org/10.1080/14992027.2021.1998676

Objectives: In the personalisation of hearing-aid fittings, gain is often adjusted to suit patient preferences using live speech. When using brief sentences as stimuli, the minimum gain adjustments necessary to elicit consistent preferences (“prefere... Read More about The effect of stimulus duration on preferences for gain adjustments when listening to speech.

Clinical Trials and Outcome Measures in Adults With Hearing Loss (2021)
Journal Article
Munro, K. J., Whitmer, W. M., & Heinrich, A. (2021). Clinical Trials and Outcome Measures in Adults With Hearing Loss. Frontiers in Psychology, 12, Article 733060. https://doi.org/10.3389/fpsyg.2021.733060

Clinical trials are designed to evaluate interventions that prevent, diagnose or treat a health condition and provide the evidence base for improving practice in health care. Many health professionals, including those working within or allied to hear... Read More about Clinical Trials and Outcome Measures in Adults With Hearing Loss.

Tinnitus prevalence in Europe: a multi-country cross-sectional population study (2021)
Journal Article
Biswas, R., Lugo, A., Akeroyd, M., Schlee, W., Gallus, S., & Hall, D. (2022). Tinnitus prevalence in Europe: a multi-country cross-sectional population study. Lancet Regional Health – Europe, 12, Article 100250. https://doi.org/10.1016/j.lanepe.2021.100250

Background Tinnitus prevalence studies report large variability across countries that might be due to inconsistent research methods. Our study aimed to report a single Pan-European estimate for tinnitus prevalence and investigate the effect of indiv... Read More about Tinnitus prevalence in Europe: a multi-country cross-sectional population study.

Dysregulated anterior insula reactivity as robust functional biomarker for chronic pain—Meta-analytic evidence from neuroimaging studies (2021)
Journal Article
Ferraro, S., Klugah-Brown, B., Tench, C. R., Yao, S., Nigri, A., Demichelis, G., …Becker, B. (2022). Dysregulated anterior insula reactivity as robust functional biomarker for chronic pain—Meta-analytic evidence from neuroimaging studies. Human Brain Mapping, 43(3), 998-1010. https://doi.org/10.1002/hbm.25702

Neurobiological pain models propose that chronic pain is accompanied by neurofunctional changes that mediate pain processing dysfunctions. In contrast, meta-analyses of neuroimaging studies in chronic pain conditions have not revealed convergent evid... Read More about Dysregulated anterior insula reactivity as robust functional biomarker for chronic pain—Meta-analytic evidence from neuroimaging studies.

Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study (2021)
Journal Article
Alyami, A., Hoad, C. L., Tench, C., Bannur, U., Clarke, C., Latief, K., …Moran, G. W. (2021). Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study. Diagnostics, 11(11), Article 2135. https://doi.org/10.3390/diagnostics11112135

Perianal Crohn’s Disease (pCD) is a common manifestation of Crohn’s Disease. Absence of reliable disease measures makes disease monitoring unreliable. Qualitative MRI has been increasingly used for diagnosing and monitoring pCD and has shown potentia... Read More about Quantitative magnetic resonance imaging in perianal crohn’s disease at 1.5 and 3.0 T: A feasibility study.

Juxtacellular Labeling of Stellate, Disk and Basket Neurons in the Central Nucleus of the Guinea Pig Inferior Colliculus (2021)
Journal Article
Wallace, M. N., Shackleton, T. M., Thompson, Z., & Palmer, A. R. (2021). Juxtacellular Labeling of Stellate, Disk and Basket Neurons in the Central Nucleus of the Guinea Pig Inferior Colliculus. Frontiers in Neural Circuits, 15, 1-24. https://doi.org/10.3389/fncir.2021.721015

We reconstructed the intrinsic axons of 32 neurons in the guinea pig inferior colliculus (IC) following juxtacellular labeling. Biocytin was injected into cells in vivo, after first analyzing physiological response properties. Based on axonal morphol... Read More about Juxtacellular Labeling of Stellate, Disk and Basket Neurons in the Central Nucleus of the Guinea Pig Inferior Colliculus.

Associations of Early Systolic Blood Pressure Control and Outcome after Thrombolysis-Eligible Acute Ischemic Stroke: Results from the ENCHANTED Study (2021)
Journal Article
Wang, X., Minhas, J. S., Moullaali, T. J., Luca Di Tanna, G., Lindley, R. I., Chen, X., …Robinson, T. G. (2022). Associations of Early Systolic Blood Pressure Control and Outcome after Thrombolysis-Eligible Acute Ischemic Stroke: Results from the ENCHANTED Study. Stroke, 53(3), 779-787. https://doi.org/10.1161/strokeaha.121.034580

Background and Purpose: In thrombolysis-eligible patients with acute ischemic stroke, there is uncertainty over the most appropriate systolic blood pressure (SBP) lowering profile that provides an optimal balance of potential benefit (functional reco... Read More about Associations of Early Systolic Blood Pressure Control and Outcome after Thrombolysis-Eligible Acute Ischemic Stroke: Results from the ENCHANTED Study.

COVID-19 Vaccine Response in People with Multiple Sclerosis (2021)
Journal Article
Tallantyre, E. C., Vickaryous, N., Anderson, V., Asardag, A. N., Baker, D., Bestwick, J., …Dobson, R. (2022). COVID-19 Vaccine Response in People with Multiple Sclerosis. Annals of Neurology, 91(1), 89-100. https://doi.org/10.1002/ana.26251

Objective: The purpose of this study was to investigate the effect of disease modifying therapies on immune response to severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) vaccines in people with multiple sclerosis (MS). Methods: Four hundre... Read More about COVID-19 Vaccine Response in People with Multiple Sclerosis.