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Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy (2019)
Journal Article
Voets, N. L., Alvarez, I., Qiu, D., Leatherday, C., Willie, J. T., Sotiropoulos, S., …Drane, D. L. (2019). Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy. Stereotactic and Functional Neurosurgery, 97(4), 255–265. https://doi.org/10.1159/000502701

Selective laser amygdalohippocampotomy (SLAH) is a minimally invasive surgical treatment for medial temporal lobe epilepsy. Visual field deficits (VFDs) are a significant potential complication. The objective of this study was to determine the relati... Read More about Mechanisms and Risk Factors Contributing to Visual Field Deficits following Stereotactic Laser Amygdalohippocampotomy.

Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma (2019)
Journal Article
Detappe, A., Reidy, M., Yu, Y., Mathieu, C., Nguyen, H. V.-T., Coroller, T. P., …Ghoroghchian, P. P. (2019). Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma. Nanoscale, 11(43), 20485-20496. https://doi.org/10.1039/c9nr06512a

Monitoring malignant progression and disease recurrence post-therapy are central challenges to improving the outcomes of patients with multiple myeloma (MM). Whereas current detection methods that rely upon bone marrow examination allow for precise m... Read More about Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma.

Coordinate based meta-analysis of networks in neuroimaging studies (2019)
Journal Article
Tench, C., Tanasescu, R., Constantinescu, C., Cottam, W., & Auer, D. (2020). Coordinate based meta-analysis of networks in neuroimaging studies. NeuroImage, 205, 1-12. https://doi.org/10.1016/j.neuroimage.2019.116259

Meta-analysis of summary results from published neuroimaging studies independently testing a common hypothesis is performed using coordinate based meta-analysis (CBMA), which tests for consistent activation (in the case of functional MRI studies) of... Read More about Coordinate based meta-analysis of networks in neuroimaging studies.

Calibration of arterial spin labeling data—potential pitfalls in post‐processing (2019)
Journal Article
Pinto, J., Chappell, M. A., Okell, T. W., Mezue, M., Segerdahl, A. R., Tracey, I., …Figueiredo, P. (2020). Calibration of arterial spin labeling data—potential pitfalls in post‐processing. Magnetic Resonance in Medicine, 83(4), 1222-1234. https://doi.org/10.1002/mrm.28000

Purpose
To assess the impact of the different post‐processing options in the calibration of arterial spin labeling (ASL) data on perfusion quantification and its reproducibility.

Theory and Methods
Absolute quantification of perfusion measuremen... Read More about Calibration of arterial spin labeling data—potential pitfalls in post‐processing.

The efficacy of statins as otoprotective agents: A systematic review (2019)
Journal Article
Prayuenyong, P., Kasbekar, A. V., & Baguley, D. M. (2020). The efficacy of statins as otoprotective agents: A systematic review. Clinical Otolaryngology, 45(1), 21-31. https://doi.org/10.1111/coa.13457

Objective: This systematic review examined the current literature, summarized research findings and identified research gaps regarding the efficacy of statins on audiological outcomes.

Methods: Systematic search of electronic databases and grey l... Read More about The efficacy of statins as otoprotective agents: A systematic review.

Large‐scale network dysfunction in vascular cognitive disorder supports connectional diaschisis in advanced arteriosclerosis (2019)
Journal Article
Meng, D., Hosseini, A. A., Simpson, R. J., Welton, T., Dineen, R. A., & Auer, D. P. (2019). Large‐scale network dysfunction in vascular cognitive disorder supports connectional diaschisis in advanced arteriosclerosis. European Journal of Neurology, https://doi.org/10.1111/ene.14084

Background and Purpose
The interrelation of cognitive performance, cerebrovascular damage and brain functional connectivity (FC) in advanced arteriosclerosis remains unclear. Our aim was to investigate the associations between FC, white matter damag... Read More about Large‐scale network dysfunction in vascular cognitive disorder supports connectional diaschisis in advanced arteriosclerosis.

Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging (2019)
Journal Article
Chou, I.-J., Tanasescu, R., Mougin, O. E., Gowland, P. A., Tench, C. R., Whitehouse, W. P., …Constantinescu, C. S. (2019). Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging. Scientific Reports, 9, Article 14378. https://doi.org/10.1038/s41598-019-50928-0

Whether the integrity of normal-appearing white matter (NAWM) is preserved in neuromyelitis optica spectrum disorders (NMOSD) is open to debate. To examine whether the tissue integrity of NAWM in NMOSD is compromised compared to that in healthy contr... Read More about Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging.

Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage (2019)
Journal Article
Bath, P. M., Woodhouse, L. J., Krishnan, K., Appleton, J. P., Anderson, C. S., Berge, E., …Sprigg, N. (2019). Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage. Stroke, 50(11), 3064-3071. https://doi.org/10.1161/STROKEAHA.119.026389

Background and Purpose—
Pilot trials suggest that glyceryl trinitrate (GTN; nitroglycerin) may improve outcome when administered early after stroke onset.

Methods—
We undertook a multicentre, paramedic-delivered, ambulance-based, prospective ran... Read More about Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage.

Biofeedback fixation training method for improving eccentric vision in patients with loss of foveal function secondary to different maculopathies (2019)
Journal Article
Morales, M. U., Saker, S., Wilde, C., Rubinstein, M., Limoli, P., & Amoaku, W. M. (2020). Biofeedback fixation training method for improving eccentric vision in patients with loss of foveal function secondary to different maculopathies. International Ophthalmology, 40, 305–312. https://doi.org/10.1007/s10792-019-01180-y

© 2019, The Author(s). Purpose: Fixation stability (FS) of the preferred retinal locus (PRL) may be improved by biofeedback fixation training (BFT) with microperimetry. Such training can be done on the patient’s PRL or in different retinal loci with... Read More about Biofeedback fixation training method for improving eccentric vision in patients with loss of foveal function secondary to different maculopathies.

The association between subcortical and cortical fMRI and lifetime noise exposure in listeners with normal hearing thresholds (2019)
Journal Article
Dewey, R. S., Francis, S. T., Guest, H., Prendergast, G., Millman, R. E., Plack, C. J., & Hall, D. A. (2020). The association between subcortical and cortical fMRI and lifetime noise exposure in listeners with normal hearing thresholds. NeuroImage, 204, Article 116239. https://doi.org/10.1016/j.neuroimage.2019.116239

© 2019 In animal models, exposure to high noise levels can cause permanent damage to hair-cell synapses (cochlear synaptopathy) for high-threshold auditory nerve fibers without affecting sensitivity to quiet sounds. This has been confirmed in several... Read More about The association between subcortical and cortical fMRI and lifetime noise exposure in listeners with normal hearing thresholds.

Shedding Light On The Human Auditory Cortex: A Review Of The Advances In Near Infrared Spectroscopy (NIRS) (2019)
Journal Article
Harrison, S., & Hartley, D. (2019). Shedding Light On The Human Auditory Cortex: A Review Of The Advances In Near Infrared Spectroscopy (NIRS). Reports in Medical Imaging, 12, 31-42. https://doi.org/10.2147/rmi.s174633

Imaging the auditory cortex can prove challenging using neuroimaging methodologies due to interfering noise from the scanner in fMRI and the low spatial resolution of EEG. Optical imaging provides a new and exciting option for exploring this key cort... Read More about Shedding Light On The Human Auditory Cortex: A Review Of The Advances In Near Infrared Spectroscopy (NIRS).

Mathematical and Computational Modelling in Critical Illness (2019)
Journal Article
Laviola, M., Bates, D. G., & Hardman, J. G. (2019). Mathematical and Computational Modelling in Critical Illness. European Respiratory & Pulmonary Diseases, 5(1),

Mathematical and computational modelling are assuming a prominent role in investigating the complex pathophysiological states and therapeutic strategies in critical illness. This editorial briefly illustrates the models of the respiratory and cardiov... Read More about Mathematical and Computational Modelling in Critical Illness.

Urokinase Plasminogen Activator: A Potential Thrombolytic Agent for Ischaemic Stroke (2019)
Journal Article
Kadir, R. R. A., & Bayraktutan, U. (2019). Urokinase Plasminogen Activator: A Potential Thrombolytic Agent for Ischaemic Stroke. Cellular and Molecular Neurobiology, 40, 347-355. https://doi.org/10.1007/s10571-019-00737-w

Stroke continues to be one of the leading causes of mortality and morbidity worldwide. Restoration of cerebral blood flow by recombinant plasminogen activator (rtPA) with or without mechanical thrombectomy is considered the most effective therapy for... Read More about Urokinase Plasminogen Activator: A Potential Thrombolytic Agent for Ischaemic Stroke.

Cancer survivors treated with platinum-based chemotherapy affected by ototoxicity and the impact on quality of life: a narrative synthesis systematic review (2019)
Journal Article
Pearson, S. E., Taylor, J., Patel, P., & Baguley, D. M. (2019). Cancer survivors treated with platinum-based chemotherapy affected by ototoxicity and the impact on quality of life: a narrative synthesis systematic review. International Journal of Audiology, 58(11), 685-695. https://doi.org/10.1080/14992027.2019.1660918

© 2019, © 2019 British Society of Audiology, International Society of Audiology, and Nordic Audiological Society. Objective: To identify any change in quality of life (QoL) caused by chemotherapy-induced toxicities, such as hearing loss and tinnitus,... Read More about Cancer survivors treated with platinum-based chemotherapy affected by ototoxicity and the impact on quality of life: a narrative synthesis systematic review.

On the interaction of head and gaze control with acoustic beam width of a simulated beamformer in a two-talker scenario (2019)
Journal Article
Hládek, Ľ., Porr, B., Naylor, G., Lunner, T., & Owen Brimijoin, W. (2019). On the interaction of head and gaze control with acoustic beam width of a simulated beamformer in a two-talker scenario. Trends in Hearing, 23, 1-12. https://doi.org/10.1177/2331216519876795

Superdirectional acoustic beamforming technology provides a high signal-to-noise ratio, but potential speech intelligibility benefits to hearing aid users are limited by the way the users move their heads. Steering the beamformer using eye gaze inste... Read More about On the interaction of head and gaze control with acoustic beam width of a simulated beamformer in a two-talker scenario.

Cathelicidin-Derived Synthetic Peptide Improves Therapeutic Potential of Vancomycin Against Pseudomonas aeruginosa (2019)
Journal Article
Mohammed, I., Said, D. G., Nubile, M., Mastropasqua, L., & Dua, H. S. (2019). Cathelicidin-Derived Synthetic Peptide Improves Therapeutic Potential of Vancomycin Against Pseudomonas aeruginosa. Frontiers in Microbiology, 10, Article 2190. https://doi.org/10.3389/fmicb.2019.02190

© Copyright © 2019 Mohammed, Said, Nubile, Mastropasqua and Dua. Pseudomonas aeruginosa (PA) is the leading cause of corneal blindness worldwide. A constant increase in multi-drug resistant PA strains have heightened the challenge of effectively mana... Read More about Cathelicidin-Derived Synthetic Peptide Improves Therapeutic Potential of Vancomycin Against Pseudomonas aeruginosa.

Understanding user reactions and interactions with an Internet-based intervention for tinnitus self-management: Mixed-methods evaluation (2019)
Journal Article
Greenwell, K., Sereda, M., Coulson, N. S., & Hoare, D. J. (2019). Understanding user reactions and interactions with an Internet-based intervention for tinnitus self-management: Mixed-methods evaluation. American Journal of Audiology, 28(3), 697-713. https://doi.org/10.1044/2019_AJA-18-0171

Purpose: Internet-based interventions have the potential to reduce the disparity in access to psychological therapy that people with tinnitus currently experience. One example is the Tinnitus E-Programme, which although freely available online, has n... Read More about Understanding user reactions and interactions with an Internet-based intervention for tinnitus self-management: Mixed-methods evaluation.

Quantification of cerebral perfusion and cerebrovascular reserve using Turbo‐QUASAR arterial spin labeling MRI (2019)
Journal Article
Zhao, M. Y., Václavů, L., Petersen, E. T., Biemond, B. J., Sokolska, M. J., Suzuki, Y., …Chappell, M. A. (2020). Quantification of cerebral perfusion and cerebrovascular reserve using Turbo‐QUASAR arterial spin labeling MRI. Magnetic Resonance in Medicine, 83(2), 731-748. https://doi.org/10.1002/mrm.27956

Purpose
To compare cerebral blood flow (CBF) and cerebrovascular reserve (CVR) quantification from Turbo‐QUASAR (quantitative signal targeting with alternating radiofrequency labeling of arterial regions) arterial spin labeling (ASL) and single post... Read More about Quantification of cerebral perfusion and cerebrovascular reserve using Turbo‐QUASAR arterial spin labeling MRI.