Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2þ/CaMKK2 Signaling to Enhance Tumor Cell Survival
(2017)
Journal Article
Vara-Ciruelos, D., Dandapani, M., Gray, A., Egbani, E. O., Evans, A. M., & Hardie, D. G. (2018). Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2þ/CaMKK2 Signaling to Enhance Tumor Cell Survival. Molecular Cancer Research, 16(2), 345-357. https://doi.org/10.1158/1541-7786.mcr-17-0323
2017 American Association for Cancer Research. Many genotoxic cancer treatments activate AMP-activated protein kinase (AMPK), but the mechanisms of AMPK activation in response to DNA damage, and its downstream consequences, have been unclear. In this... Read More about Genotoxic Damage Activates the AMPK-α1 Isoform in the Nucleus via Ca2þ/CaMKK2 Signaling to Enhance Tumor Cell Survival.