All Outputs (139)

Cattle farmers’ perception of biosecurity measures and the main predictors of behaviour change: The first European-wide pilot study (2020)
Journal Article
Renault, V., Damiaans, B., Humblet, M., Jiménez Ruiz, S., García Bocanegra, I., Brennan, M. L., …Saegerman, C. (2021). Cattle farmers’ perception of biosecurity measures and the main predictors of behaviour change: The first European-wide pilot study. Transboundary and Emerging Diseases, 68(6), 3305-3319. https://doi.org/10.1111/tbed.13935

The importance of biosecurity as a strategy to prevent and control infectious diseases has increased substantially over the last few decades. Several studies have reported a low implementation level of biosecurity measures (BSM), particularly in catt... Read More about Cattle farmers’ perception of biosecurity measures and the main predictors of behaviour change: The first European-wide pilot study.

Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection (2020)
Journal Article
Zou, Y., Zheng, W., He, J., Elsheikha, H. M., Zhu, X., & Lu, Y. (2020). Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.587273

Toxocara canis is a neglected zoonotic parasite, which threatens the health of dogs and humans worldwide. The molecular mechanisms that underlie the progression of T. canis infection remain mostly unknown. MicroRNAs (miRNAs) are small non-coding RNAs... Read More about Toxocara canis Differentially Affects Hepatic MicroRNA Expression in Beagle Dogs at Different Stages of Infection.

Retrospective serological survey for influenza in horses from Brazil (2020)
Journal Article
Daly, J. M., Megid, J., Langoni, H., de Nardi Júnior, G., & Ribeiro, M. G. (2021). Retrospective serological survey for influenza in horses from Brazil. Brazilian Journal of Microbiology, 52(1), 461-466. https://doi.org/10.1007/s42770-020-00398-8

Equine influenza (EI) virus is one of the most economically important pathogens of respiratory diseases of horses worldwide. Despite availability of vaccines for control of EI, the highly contagious nature and variability properties of the virus mean... Read More about Retrospective serological survey for influenza in horses from Brazil.

Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis (2020)
Journal Article
England, G., Rijsselaere, T., Campbell, A., Moxon, R., & Freeman, S. (2021). Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis. Theriogenology, 159, 176-183. https://doi.org/10.1016/j.theriogenology.2020.10.013

In mammalian species there are significant physiological responses of the female reproductive tract to the deposition of sperm. These are particularly notable in species where sperm are deposited directly into the uterus, and function both to facilit... Read More about Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis.

Could it be osteoarthritis? How dog owners and veterinary surgeons describe identifying canine osteoarthritis in a general practice setting (2020)
Journal Article
Belshaw, Z., Dean, R., & Asher, L. (2020). Could it be osteoarthritis? How dog owners and veterinary surgeons describe identifying canine osteoarthritis in a general practice setting. Preventive Veterinary Medicine, 185, Article 105198. https://doi.org/10.1016/j.prevetmed.2020.105198

Canine osteoarthritis is a common, painful condition that is typically managed in a general practice setting. Osteoarthritis may have significant negative impacts on the welfare of both dogs and their owners. Anticipated early clinical signs of canin... Read More about Could it be osteoarthritis? How dog owners and veterinary surgeons describe identifying canine osteoarthritis in a general practice setting.

Impact of Flock Health Clubs (2020)
Journal Article
Noble, N., Occhiuto, F., Lovatt, F., Johnson, M., Jones, W., & Kaler, J. (2020). Impact of Flock Health Clubs. Livestock, 25(6), 301-307. https://doi.org/10.12968/live.2020.25.6.301

Sheep farming is an important part of UK agriculture with significantly more breeding females than either the pig or cattle sectors. Whether grazing alongside arable rotations or utilising the marginal uplands, sheep farms arguably play a key role th... Read More about Impact of Flock Health Clubs.

Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells (2020)
Journal Article
Pérez-Cota, F., Fuentes-Domínguez, R., La Cavera III, S., Hardiman, W., Yao, M., Setchfield, K., …Clark, M. (2020). Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells. Journal of Applied Physics, 128(16), Article 160902. https://doi.org/10.1063/5.0023744

© 2020 Author(s). Characterization of the elasticity of biological cells is growing as a new way to gain insight into cell biology. Cell mechanics are related to most aspects of cellular behavior, and applications in research and medicine are broad.... Read More about Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells.

Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts (2020)
Journal Article
Hu, R., He, J., Elsheikha, H. M., Zou, Y., Ehsan, M., Ma, Q., …Cong, W. (2020). Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts. Frontiers in Microbiology, 11, Article 570903. https://doi.org/10.3389/fmicb.2020.570903

Infection by the protozoan Toxoplasma gondii can have a devastating impact on the structure and function of the brain of the infected individuals, particularly immunocompromised patients. A systems biology view of the brain transcriptome can identify... Read More about Transcriptomic Profiling of Mouse Brain During Acute and Chronic Infections by Toxoplasma gondii Oocysts.

Tumor Spheroids And Organoids Encyclopedia (2020)
Other
Rutland, C. (in press). Tumor Spheroids And Organoids Encyclopedia

Understanding and investigating tumors is carried out by researchers using a number of different methods. One exciting and promising area is 3D tumor models including spheriod and organoid models. They act in similar ways to tumors which means we can... Read More about Tumor Spheroids And Organoids Encyclopedia.

Global profiling of lysine 2-hydroxyisobutyrylome in Toxoplasma gondii using affinity purification mass spectrometry (2020)
Journal Article
Nie, L.-B., Liang, Q.-L., Elsheikha, H. M., Du, R., Zhu, X.-Q., & Li, F.-C. (2020). Global profiling of lysine 2-hydroxyisobutyrylome in Toxoplasma gondii using affinity purification mass spectrometry. Parasitology Research, 119(12), 4061-4071. https://doi.org/10.1007/s00436-020-06923-w

Lysine 2-hydroxyisobutyrylation (Khib) is a recently discovered and evolutionarily conserved form of protein post-translational modification (PTM) found in mammalian and yeast cells. Previous studies have shown that Khib plays roles in the activity o... Read More about Global profiling of lysine 2-hydroxyisobutyrylome in Toxoplasma gondii using affinity purification mass spectrometry.

Classification of portosystemic shunts entering the caudal vena cava at the omental foramen in dogs (2020)
Journal Article
White, R., Warren-Smith, C., Shales, C., & Parry, A. (2020). Classification of portosystemic shunts entering the caudal vena cava at the omental foramen in dogs. Journal of Small Animal Practice, 61(11), 659-668. https://doi.org/10.1111/jsap.13209

Objective To re‐evaluate the anatomy and classification of congenital extrahepatic portosystemic shunts entering the caudal vena cava at the level of the omental foramen. Material and Methods A retrospective review of a consecutive series of... Read More about Classification of portosystemic shunts entering the caudal vena cava at the omental foramen in dogs.

Apoptosis in Cancer Cells Is Induced by Alternative Splicing of hnRNPA2/B1 Through Splicing of Bcl-x, a Mechanism that Can Be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata (2020)
Journal Article
Makhafola, T. J., Mbele, M., Yacqub-Usman, K., Hendren, A., Haigh, D. B., Blackley, Z., …Dlamini, Z. (2020). Apoptosis in Cancer Cells Is Induced by Alternative Splicing of hnRNPA2/B1 Through Splicing of Bcl-x, a Mechanism that Can Be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata. Frontiers in Oncology, 10, Article 547392. https://doi.org/10.3389/fonc.2020.547392

Alternative splicing is deregulated in cancer and alternatively spliced products can be linked to cancer hallmarks. Targeting alternative splicing could offer novel effective cancer treatments. We investigated the effects of the crude extract of a So... Read More about Apoptosis in Cancer Cells Is Induced by Alternative Splicing of hnRNPA2/B1 Through Splicing of Bcl-x, a Mechanism that Can Be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata.

Systematic review and meta‐analysis of seroprevalence studies of West Nile virus in equids in Europe between 2001 and 2018 (2020)
Journal Article
Metz, M. B. C., Olufemi, O. T., Daly, J. M., & Barba, M. (2021). Systematic review and meta‐analysis of seroprevalence studies of West Nile virus in equids in Europe between 2001 and 2018. Transboundary and Emerging Diseases, 68(4), 1814-1823. https://doi.org/10.1111/tbed.13866

There is some evidence that West Nile virus (WNV), which causes encephalomyelitis in equids, is an emerging disease in Europe. The aim of this study was to perform a systematic review and meta-analysis to determine the seroprevalence of West Nile vir... Read More about Systematic review and meta‐analysis of seroprevalence studies of West Nile virus in equids in Europe between 2001 and 2018.

Hearts, and the Heartless, in the Animal Kingdom (2020)
Journal Article
Alibhai, A., Stanford, K., Rutland, S., & Rutland, C. S. (in press). Hearts, and the Heartless, in the Animal Kingdom. Frontiers for Young Minds, 8, Article 540440. https://doi.org/10.3389/frym.2020.540440

We all take our hearts for granted: the fascinating organ inside everyone that beats continuously to keep blood pumping through our bodies. Blood flow ensures that oxygen, nutrients from food, hormones, and waste products get to the correct cells. Th... Read More about Hearts, and the Heartless, in the Animal Kingdom.

Viruses of protozoan parasites and viral therapy: Is the time now right? (2020)
Journal Article
Barrow, P., Dujardin, J. C., Fasel, N., Greenwood, A. D., Osterrieder, K., Lomonossoff, G., …Lalle, M. (2020). Viruses of protozoan parasites and viral therapy: Is the time now right?. Virology Journal, 17, Article 142. https://doi.org/10.1186/s12985-020-01410-1

Infections caused by protozoan parasites burden the world with huge costs in terms of human and animal health. Most parasitic diseases caused by protozoans are neglected, particularly those associated with poverty and tropical countries, but the pauc... Read More about Viruses of protozoan parasites and viral therapy: Is the time now right?.

Global profiling of lncRNAs-miRNAs-mRNAs reveals differential expression of coding genes and non-coding RNAs in the lung of beagle dogs at different stages of Toxocara canis infection (2020)
Journal Article
Zheng, W.-B., Zou, Y., He, J.-J., Elsheikha, H. M., Liu, G.-H., Hu, M.-H., …Zhu, X.-Q. (2021). Global profiling of lncRNAs-miRNAs-mRNAs reveals differential expression of coding genes and non-coding RNAs in the lung of beagle dogs at different stages of Toxocara canis infection. International Journal for Parasitology, 51(1), 49-61. https://doi.org/10.1016/j.ijpara.2020.07.014

The roundworm Toxocara canis causes toxocariasis in dogs and larval migrans in humans. Better understanding of the lung response to T. canis infection could explain why T. canis must migrate to and undergoes part of its development inside the lung of... Read More about Global profiling of lncRNAs-miRNAs-mRNAs reveals differential expression of coding genes and non-coding RNAs in the lung of beagle dogs at different stages of Toxocara canis infection.

Thapsigargin at non-cytotoxic levels induces a potent host antiviral response that blocks influenza a virus replication (2020)
Journal Article
Goulding, L. V., Yang, J., Jiang, Z., Zhang, H., Lea, D., Emes, R. D., …Chang, K. C. (2020). Thapsigargin at non-cytotoxic levels induces a potent host antiviral response that blocks influenza a virus replication. Viruses, 12(10), Article 1093. https://doi.org/10.3390/v12101093

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Influenza A... Read More about Thapsigargin at non-cytotoxic levels induces a potent host antiviral response that blocks influenza a virus replication.

Critical Impact of Different Conserved Endoplasmic Retention Motifs and Dopamine Receptor Interacting Proteins (DRIPs) on Intracellular Localization and Trafficking of the D2 Dopamine Receptor (D2-R) Isoforms (2020)
Journal Article
Blagotinšek Cokan, K., Mavri, M., Rutland, C. S., Glišić, S., Senćanski, M., Vrecl, M., & Kubale, V. (2020). Critical Impact of Different Conserved Endoplasmic Retention Motifs and Dopamine Receptor Interacting Proteins (DRIPs) on Intracellular Localization and Trafficking of the D2 Dopamine Receptor (D2-R) Isoforms. Biomolecules, 10(10), Article 1355. https://doi.org/10.3390/biom10101355

The type 2 dopamine receptor D2 (D2-R), member of the G protein-coupled receptor (GPCR) superfamily, exists in two isoforms, short (D2S-R) and long (D2L-R). They differ by an additional 29 amino acids (AA) in the third cytoplasmic loop (ICL3) of the... Read More about Critical Impact of Different Conserved Endoplasmic Retention Motifs and Dopamine Receptor Interacting Proteins (DRIPs) on Intracellular Localization and Trafficking of the D2 Dopamine Receptor (D2-R) Isoforms.

Promising Applications of Tumor Spheroids and Organoids for Personalized Medicine (2020)
Journal Article
Gilazieva, Z., Ponomarev, A., Rutland, C., Rizvanov, A., & Solovyeva, V. (2020). Promising Applications of Tumor Spheroids and Organoids for Personalized Medicine. Cancers, 12(10), Article 2727. https://doi.org/10.3390/cancers12102727

One of the promising directions in personalized medicine is the use of three-dimensional (3D) tumor models such as spheroids and organoids. Spheroids and organoids are three-dimensional cultures of tumor cells that can be obtained from patient tissue... Read More about Promising Applications of Tumor Spheroids and Organoids for Personalized Medicine.

Acetylome analysis of the feline small intestine following Toxoplasma gondii infection (2020)
Journal Article
Meng, Y., Zhai, B., Elsheikha, H. M., Xie, S., Wang, Z., Zhao, Q., …He, J. (2020). Acetylome analysis of the feline small intestine following Toxoplasma gondii infection. Parasitology Research, 119(11), 3649-3657. https://doi.org/10.1007/s00436-020-06880-4

Toxoplasma gondii is a protozoan parasite capable of infecting a large number of warm-blooded animals and causes serious health complications in immunocompromised patients. T. gondii infection of the feline small intestine is critical for the complet... Read More about Acetylome analysis of the feline small intestine following Toxoplasma gondii infection.