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All Outputs (2211)

Effects of NAD at purine receptors in isolated blood vessels (2014)
Journal Article
Alefishat, E., Alexander, S. P., & Ralevic, V. (2015). Effects of NAD at purine receptors in isolated blood vessels. Purinergic Signalling, 11(1), https://doi.org/10.1007/s11302-014-9428-1

Nicotinamide adenine dinucleotide (NAD) belongs to the family of naturally occurring adenine dinucleotides, best known for their various intracellular roles. However, there is evidence that they can also be released from cells to act as novel extrace... Read More about Effects of NAD at purine receptors in isolated blood vessels.

Origins of major archaeal clades correspond to gene acquisitions from bacteria (2014)
Journal Article
Nelson-Sathi, S., Sousa, F. L., Roettger, M., Lozada-Chavez, N., Thiergart, T., Janssen, A., …Martin, W. F. (2015). Origins of major archaeal clades correspond to gene acquisitions from bacteria. Nature, 517(7532), 77-80. https://doi.org/10.1038/nature13805

The mechanisms that underlie the origin of major prokaryotic groups are poorly understood. In principle, the origin of both species and higher taxa among prokaryotes should entail similar mechanisms--ecological interactions with the environment paire... Read More about Origins of major archaeal clades correspond to gene acquisitions from bacteria.

Development and validation of protein microarray technology for simultaneous inflammatory mediator detection in human sera (2014)
Journal Article
Selvarajah, S., Negm, O. H., Hamed, M. R., Tubby, C., Todd, I., Tighe, P. J., …Fairclough, L. C. (2014). Development and validation of protein microarray technology for simultaneous inflammatory mediator detection in human sera. Mediators of Inflammation, 2014, 1-12. https://doi.org/10.1155/2014/820304

© 2014 Senthooran Selvarajah et al. Biomarkers, including cytokines, can help in the diagnosis, prognosis, and prediction of treatment response across a wide range of disease settings. Consequently, the recent emergence of protein microarray technolo... Read More about Development and validation of protein microarray technology for simultaneous inflammatory mediator detection in human sera.

Molecular Evidence for Cryptic Speciation in the Cyclophorus fulguratus (Pfeiffer, 1854) Species Complex (Caenogastropoda: Cyclophoridae) with Description of New Species. (2014)
Journal Article

A high degree of intraspecific variation, both genetic and in shell morphology, of the operculate land snail Cyclophorus fulguratus (Pfeiffer, 1854) suggests that its classification as a single species warrants reconsideration. We sequenced two nucle... Read More about Molecular Evidence for Cryptic Speciation in the Cyclophorus fulguratus (Pfeiffer, 1854) Species Complex (Caenogastropoda: Cyclophoridae) with Description of New Species..

Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis (2014)
Journal Article
Alqahtani, F. Y. S., Mahdavi, J., Wheldon, L. M., Vassey, M., Pirinccioglu, N., Royer, P.-J., …Ala'Aldeen, D. A. (2014). Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis. Open Biology, 4(10), Article 140053. https://doi.org/10.1098/rsob.140053

The non-integrin laminin receptor (LAMR1/RPSA) and galectin-3 (Gal-3) are multi-functional host molecules with roles in diverse pathological processes, particularly of infectious or oncogenic origins. Using bimolecular fluorescence complementation an... Read More about Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis.

Surgical materials: Current challenges and nano-enabled solutions (2014)
Journal Article
Annabi, N., Tamayol, A., Shin, S. R., Ghaemmaghami, A. M., Peppas, N. A., & Khademhosseini, A. (2014). Surgical materials: Current challenges and nano-enabled solutions. Nano Today, 9(5), 574-589. https://doi.org/10.1016/j.nantod.2014.09.006

© 2014 Elsevier Ltd. All rights reserved. Surgical adhesive biomaterials have emerged as substitutes to sutures and staples in many clinical applications. Nano-enabled materials containing nanoparticles or having a distinct nanotopography have been u... Read More about Surgical materials: Current challenges and nano-enabled solutions.

Revision workshops in elementary mathematics enhance student performance in routine laboratory calculations (2014)
Journal Article
Sawbridge, J. L., Qureshi, H. K., Boyd, M. J., & Brown, A. M. (2014). Revision workshops in elementary mathematics enhance student performance in routine laboratory calculations. Advances in Physiology Education, 38(3), 239-245. https://doi.org/10.1152/advan.00036.2014

The ability to understand and implement calculations required for molarity and dilution computations that are routinely undertaken in the laboratory are essential skills that should be possessed by all students entering an undergraduate Life Sciences... Read More about Revision workshops in elementary mathematics enhance student performance in routine laboratory calculations.

A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries (2014)
Journal Article
Wong, P., Garle, M., Alexander, S., Randall, M., & Roberts, R. (2014). A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries. Pharmacological Research, 90, https://doi.org/10.1016/j.phrs.2014.09.004

Hydrogen peroxide (H2O2) has been proposed to act as a factor for endothelium-derived hyperpolar-ization (EDH) and EDH may act as a ‘back up’ system to compensate the loss of the NO pathway. Here,the mechanism of action of H2O2in porcine isolated cor... Read More about A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries.

Development of ten microsatellite loci in the invasive giant African land snail, Achatina (=Lissachatina) fulica Bowdich, 1822 (2014)
Journal Article
Morrison, C. L., Springmann, M. J., Iwanowicz, D. D., & Wade, C. M. (2015). Development of ten microsatellite loci in the invasive giant African land snail, Achatina (=Lissachatina) fulica Bowdich, 1822. Conservation Genetics Resources, 7(1), 201-202. https://doi.org/10.1007/s12686-014-0332-3

© 2014, Springer Science+Business Media Dordrecht (outside the USA). A suite of tetra-nucleotide microsatellite loci were developed for the invasive giant African land snail, Achatina (=Lissachatina) fulica Bowdich, 1822, from Ion Torrent next-genera... Read More about Development of ten microsatellite loci in the invasive giant African land snail, Achatina (=Lissachatina) fulica Bowdich, 1822.

Raised tone reveals ATP as a sympathetic neurotransmitter in the porcine mesenteric arterial bed (2014)
Journal Article
Shatarat, A., Dunn, W. R., & Ralevic, V. (in press). Raised tone reveals ATP as a sympathetic neurotransmitter in the porcine mesenteric arterial bed. Purinergic Signalling, 10(4), https://doi.org/10.1007/s11302-014-9426-3

The relative importance of ATP as a functional sympathetic neurotransmitter in blood vessels has been shown to be increased when the level of preexisting vascular tone or pressure is increased, in studies carried out in rat mesenteric arteries. The a... Read More about Raised tone reveals ATP as a sympathetic neurotransmitter in the porcine mesenteric arterial bed.

Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure (2014)
Journal Article
Haack, T., Schneider, M., Schwendele, B., & Renault, A. D. (2014). Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure. Developmental Biology, 396(2), https://doi.org/10.1016/j.ydbio.2014.08.033

The Drosophila heart is a linear organ formed by the movement of bilaterally specified progenitor cells to the midline and adherence of contralateral heart cells. This movement occurs through the attachment of heart cells to the overlying ectoderm wh... Read More about Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure.

Restricted Genetic Variation in Populations of Achatina (Lissachatina) fulica outside of East Africa and the Indian Ocean Islands Points to the Indian Ocean Islands as the Earliest Known Common Source (2014)
Journal Article

The Giant African Land Snail, Achatina (?=?Lissachatina) fulica Bowdich, 1822, is a tropical crop pest species with a widespread distribution across East Africa, the Indian subcontinent, Southeast Asia, the Pacific, the Caribbean, and North and South... Read More about Restricted Genetic Variation in Populations of Achatina (Lissachatina) fulica outside of East Africa and the Indian Ocean Islands Points to the Indian Ocean Islands as the Earliest Known Common Source.

Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation (2014)
Journal Article
Stephens, F. B., Mendis, B., Shannon, C. E., Cooper, S., Ortori, C. A., Barrett, D. A., …Tsintzas, K. (2014). Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation. Clinical Science, 127(5), 315-322. https://doi.org/10.1042/cs20140031

Acylcarnitine accumulation in skeletal muscle and plasma has been observed in numerous models of mitochondrial lipid overload and insulin resistance. Fish oil n3PUFA (omega-3 polyunsaturated fatty acids) are thought to protect against lipid-induced i... Read More about Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation.

MicroRNAs and p63 in epithelial stemness (2014)
Journal Article
Candi, E., Amelio, I., Agostini, M., & Melino, G. (2015). MicroRNAs and p63 in epithelial stemness. Cell Death and Differentiation, 22(1), 12-21. https://doi.org/10.1038/cdd.2014.113

MicroRNAs (miRs) are a class of small noncoding RNAs that suppress the expression of protein-coding genes by repressing protein translation. Although the roles that miRs and the miR processing machinery have in regulating epithelial stem cell biology... Read More about MicroRNAs and p63 in epithelial stemness.

Evolution of sweet taste perception in hummingbirds by transformation of the ancestral umami receptor (2014)
Journal Article
Baldwin, M. W., Toda, Y., Nakagita, T., O'Connell, M. J., Klasing, K. C., Misaka, T., …Liberles, S. D. (2014). Evolution of sweet taste perception in hummingbirds by transformation of the ancestral umami receptor. Science, 345(6199), 929-933. https://doi.org/10.1126/science.1255097

Sensory systems define an animal's capacity for perception and can evolve to promote survival in new environmental niches. We have uncovered a noncanonical mechanism for sweet taste perception that evolved in hummingbirds since their divergence from... Read More about Evolution of sweet taste perception in hummingbirds by transformation of the ancestral umami receptor.