All Outputs (103)

Foreword to ‘Quantitative and analytical relations in biochemistry’—a special issue in honour of Donald J. Winzor’s 80th birthday (2016)
Journal Article
Hall, D., & Harding, S. E. (2016). Foreword to ‘Quantitative and analytical relations in biochemistry’—a special issue in honour of Donald J. Winzor’s 80th birthday. Biophysical Reviews, 8(4), 269-277. https://doi.org/10.1007/s12551-016-0227-5

The purpose of this special issue is to honour Professor Donald J. Winzor’s long career as a researcher and scientific mentor, and to celebrate the milestone of his 80th birthday. Throughout his career, Don has been renowned for his development of cl... Read More about Foreword to ‘Quantitative and analytical relations in biochemistry’—a special issue in honour of Donald J. Winzor’s 80th birthday.

Refinement of the taxonomic structure of 16SrXI and 16SrXIV phytoplasmas of gramineous plants using multilocus sequence typing (2016)
Journal Article
Abeysinghe, S., Abeysinghe, P. D., Kanatiwela-de Silva, C., Udagama, P., Warawichanee, K., Aljafar, N., …Dickinson, M. (2016). Refinement of the taxonomic structure of 16SrXI and 16SrXIV phytoplasmas of gramineous plants using multilocus sequence typing. Plant Disease, 100(10), https://doi.org/10.1094/PDIS-02-16-0244-RE

Phytoplasmas that infect gramineous plants, including Napier grass stunt, sugarcane whiteleaf, sugarcane grassy shoot, and Bermuda grass whiteleaf, have been classified into two closely related groups, 16SrXI and 16SrXIV, based on the 16S ribosomal R... Read More about Refinement of the taxonomic structure of 16SrXI and 16SrXIV phytoplasmas of gramineous plants using multilocus sequence typing.

Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis (2016)
Journal Article
Ferguson, A., Pearce, S., Band, L. R., Yang, C., Ferjentsikova, I., King, J., …Wilson, Z. A. (in press). Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis. New Phytologist, 213, https://doi.org/10.1111/nph.14200

Viable pollen is essential for plant reproduction and crop yield. Its production requires coordinated expression at specific stages during anther development, involving early meiosis-associated events and late pollen wall formation. The ABORTED MICRO... Read More about Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis.

The influence of style and origin on mineral composition of beers retailing in the UK (2016)
Journal Article
Rodrigo, S., Young, S. D., Talaverano, M., & Broadley, M. R. (in press). The influence of style and origin on mineral composition of beers retailing in the UK. European Food Research and Technology, https://doi.org/10.1007/s00217-016-2805-y

Beer has high nutritional values in terms of energy and is also a dietary source of antioxidants, carbohydrates and minerals among others. In Europe, 53 Mt of beer are produced annually, and with an average supply of 68.2 kg capita‾¹ year‾¹ among adu... Read More about The influence of style and origin on mineral composition of beers retailing in the UK.

Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein (2016)
Journal Article
Abdelhameed, A. S., Morris, G. A., Almutairi, F., Adams, G. G., Duvivier, P., Conrath, K., & Harding, S. E. (in press). Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein. Scientific Reports, 6(1), 1-11. https://doi.org/10.1038/srep35588

The structural integrity of meningococcal native, micro-fluidized and activated capsular polysaccharides and their glycoconjugates – in the form most relevant to their potential use as vaccines (dilute solution) - have been investigated with respect... Read More about Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein.

Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions (2016)
Journal Article
Sarangapani, P. S., Weaver, J., Parupudi, A., Besong, T. M., Adams, G. G., Harding, S. E., …Pathak, J. A. (2016). Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions. Journal of Pharmaceutical Sciences, 105(12), https://doi.org/10.1016/j.xphs.2016.08.020

The role of antibody structure (conformation) in solution rheology is probed. It is demonstrated here that pH-dependent changes in the tertiary structure of 2 mAb solutions lead to viscoelasticity and not merely a shear viscosity (η) increase. Steady... Read More about Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions.

STAT2 is a pervasive cytokine regulator due to its inhibition of STAT1 in multiple signaling pathways (2016)
Journal Article
Ho, J., Pelzel, C., Begitt, A., Mee, M., Elsheikha, H. M., Scott, D. J., & Vinkemeier, U. (2016). STAT2 is a pervasive cytokine regulator due to its inhibition of STAT1 in multiple signaling pathways. PLoS Biology, 14(10), 1-27. https://doi.org/10.1371/journal.pbio.2000117

STAT2 is the quintessential transcription factor for type 1 interferons (IFNs), where it functions as a heterodimer with STAT1. However, the human and murine STAT2-deficient phenotypes suggest important additional and currently unidentified type 1 IF... Read More about STAT2 is a pervasive cytokine regulator due to its inhibition of STAT1 in multiple signaling pathways.

Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner (2016)
Journal Article
Kroes, A., Broekgaarden, C., Castellanos Uribe, M., May, S., van Loon, J. J., & Dicke, M. (2017). Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner. Oecologia, 183(1), 107-120. https://doi.org/10.1007/s00442-016-3758-3

Plants are commonly attacked by multiple herbivorous species. Yet, little is known about transcriptional patterns underlying plant responses to multiple insect attackers feeding simultaneously. Here, we assessed= transcriptomic responses of Arabidops... Read More about Brevicoryne brassicae aphids interfere with transcriptome responses of Arabidopsis thaliana to feeding by Plutella xylostella caterpillars in a density?dependent manner.

Effects of soil type and composition of rhizodeposits on rhizosphere priming phenomena (2016)
Journal Article
Lloyd, D. A., Ritz, K., Paterson, E., & Kirk, G. J. (2016). Effects of soil type and composition of rhizodeposits on rhizosphere priming phenomena. Soil Biology and Biochemistry, 103, https://doi.org/10.1016/j.soilbio.2016.10.002

Inputs of fresh plant-derived C may stimulate microbially-mediated turnover of soil organic matter (SOM) in the rhizosphere. But studies of such ‘priming’ effects in artificial systems often produce conflicting results, depending on such variables as... Read More about Effects of soil type and composition of rhizodeposits on rhizosphere priming phenomena.

Distinct respiratory responses of soils to complex organic substrate are governed predominantly by soil architecture and its microbial community (2016)
Journal Article
Fraser, F., Todman, L., Corstanje, R., Deeks, L., Harris, J., Pawlett, M., …Ritz, K. (in press). Distinct respiratory responses of soils to complex organic substrate are governed predominantly by soil architecture and its microbial community. Soil Biology and Biochemistry, 103, https://doi.org/10.1016/j.soilbio.2016.09.015

Factors governing the turnover of organic matter (OM) added to soils, including substrate quality, climate, environment and biology, are well known, but their relative importance has been difficult to ascertain due to the interconnected nature of the... Read More about Distinct respiratory responses of soils to complex organic substrate are governed predominantly by soil architecture and its microbial community.

The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport (2016)
Journal Article
Daniel, Z., Swali, A., Emes, R. D., & Langley-Evans, S. C. (2016). The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport. Genes and Nutrition, 11(27), https://doi.org/10.1186/s12263-016-0541-3

Fetal exposure to a maternal low protein diet during rat pregnancy is associated with hypertension, renal dysfunction and metabolic disturbance in adult life. These effects are present when dietary manipulations target only the first half of pregnanc... Read More about The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport.

Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration (2016)
Journal Article
Pollard, A., Shephard, F., Freed, J., Liddell, S., & Chakrabarti, L. (2016). Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration. Aging, 8(10), 2425-2436. https://doi.org/10.18632/aging.101064

Carbonic anhydrase inhibitors are used to treat glaucoma and cancers. Carbonic anhydrases perform a crucial role in the conversion of carbon dioxide and water into bicarbonate and protons. However, there is little information about carbonic anhydrase... Read More about Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration.

Chemotaxonomy as a tool for interpreting the cryptic diversity of Poaceae pollen (2016)
Journal Article
Julier, A. C., Jardine, P. E., Coe, A. L., Gosling, W. D., Lomax, B. H., & Fraser, W. T. (2016). Chemotaxonomy as a tool for interpreting the cryptic diversity of Poaceae pollen. Review of Palaeobotany and Palynology, 235, https://doi.org/10.1016/j.revpalbo.2016.08.004

The uniform morphology of different species of Poaceae (grass) pollen means that identification to below family level using light microscopy is extremely challenging. Poor taxonomic resolution reduces recoverable information from the grass pollen rec... Read More about Chemotaxonomy as a tool for interpreting the cryptic diversity of Poaceae pollen.

Metabolomics of aging assessed in individual parasitoid wasps (2016)
Journal Article
Kapranas, A., Snart, C. J., Williams, H. E. L., Hardy, I. C., & Barrett, D. A. (2016). Metabolomics of aging assessed in individual parasitoid wasps. Scientific Reports, 6(1), Article 34848. https://doi.org/10.1038/srep34848

Metabolomics studies of low-biomass organisms, such as small insects, have previously relied on the pooling of biological samples to overcome detection limits, particularly using NMR. We show that the differentiation of metabolite profiles of individ... Read More about Metabolomics of aging assessed in individual parasitoid wasps.

Hybrid vertex-midline modelling of elongated plant organs (2016)
Journal Article
Fozard, J. A., Bennett, M. J., King, J. R., & Jensen, O. E. (2016). Hybrid vertex-midline modelling of elongated plant organs. Interface Focus, 6(5), Article 20160043. https://doi.org/10.1098/rsfs.2016.0043

We describe a method for the simulation of the growth of elongated plant organs, such as seedling roots. By combining a midline representation of the organ on a tissue scale and a vertex-based representation on the cell scale, we obtain a multiscale... Read More about Hybrid vertex-midline modelling of elongated plant organs.

Brassinosteroids participate in the control of basal and acquired freezing tolerance of plants (2016)
Journal Article
Eremina, M., Unterholzner, S. J., Rathnayake, A. I., Castellanos, M., Khan, M., Kugler, K. G., …Poppenberger, B. (2016). Brassinosteroids participate in the control of basal and acquired freezing tolerance of plants. Proceedings of the National Academy of Sciences, 113(40), Article E5982-E5991. https://doi.org/10.1073/pnas.1611477113

Brassinosteroids (BRs) are growth-promoting plant hormones that play a role in abiotic stress responses, but molecular modes that enable this activity remain largely unknown. Here we show that BRs participate in the regulation of freezing tolerance.... Read More about Brassinosteroids participate in the control of basal and acquired freezing tolerance of plants.

Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root (2016)
Journal Article
Street, I. H., Mathews, D. E., Yamburkenko, M. V., Sorooshzadeh, A., John, R. T., Swarup, R., …Schaller, G. E. (2016). Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root. Development, 143(21), 3982-3993. https://doi.org/10.1242/dev.132035

Hormonal interactions are critical for plant development. In Arabidopsis, cytokinins inhibit root growth through effects on cell proliferation and cell elongation. Here we define key mechanistic elements in a regulatory network by which cytokinin inh... Read More about Cytokinin acts through the auxin influx carrier AUX1 to regulate cell elongation in the root.

Reproductive efficiency of the bethylid wasp Cephalonomia tarsalis: the influences of spatial structure and host density (2016)
Journal Article
Eliopoulos, P. A., Kapranas, A., Givropoulou, E., & Hardy, I. C. (in press). Reproductive efficiency of the bethylid wasp Cephalonomia tarsalis: the influences of spatial structure and host density. Bulletin of Entomological Research, https://doi.org/10.1017/S0007485316000651

The parasitoid wasp Cephalonomia tarsalis (Ashmead) (Hymenoptera: Bethylidae) is commonly present in stored product facilities. While beneficial, it does not provide a high 24 degree of biological pest control against its host, the saw-toothed beetle... Read More about Reproductive efficiency of the bethylid wasp Cephalonomia tarsalis: the influences of spatial structure and host density.

The effect of adenosine monophosphate deaminase overexpression on the accumulation of umami-related metabolites in tomatoes (2016)
Journal Article
Chew, B. L., Fisk, I. D., Fray, R., Tucker, G. A., Bodi, Z., Ferguson, A., …Seymour, G. B. (in press). The effect of adenosine monophosphate deaminase overexpression on the accumulation of umami-related metabolites in tomatoes. Plant Cell Reports, 36(1), https://doi.org/10.1007/s00299-016-2058-z

Taste is perceived as one of a combination of five sensations, sweet, sour, bitter, salty, and umami. The umami taste is best known as a savoury sensation and plays a central role in food flavour, palatability, and eating satisfaction. Umami flavour... Read More about The effect of adenosine monophosphate deaminase overexpression on the accumulation of umami-related metabolites in tomatoes.

The 4-Dimensional Plant: Effects of Wind-Induced Canopy Movement on Light Fluctuations and Photosynthesis (2016)
Journal Article
Burgess, A. J., Retkute, R., Preston, S. P., Jensen, O. E., Pound, M. P., Pridmore, T. P., & Murchie, E. H. (2016). The 4-Dimensional Plant: Effects of Wind-Induced Canopy Movement on Light Fluctuations and Photosynthesis. Frontiers in Plant Science, 7(1392), https://doi.org/10.3389/fpls.2016.01392

Physical perturbation of a plant canopy brought about by wind is a ubiquitous phenomenon and yet its biological importance has often been overlooked. This is partly due to the complexity of the issue at hand: wind-induced movement (or mechanical exci... Read More about The 4-Dimensional Plant: Effects of Wind-Induced Canopy Movement on Light Fluctuations and Photosynthesis.