Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle

Brearley-Sholto, Madelaine C.; Loczenski-Brown, David M.; Jones, Sarah; Daniel, Zoe C.T.R.; Ebling, Francis J.P.; Parr, Tim; Brameld, John M.

doi:10.1038/s41598-021-99432-4

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Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle (2021)
Journal Article
Brearley-Sholto, M. C., Loczenski-Brown, D. M., Jones, S., Daniel, Z. C., Ebling, F. J., Parr, T., & Brameld, J. M. (2021). Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle. Scientific Reports, 11(1), 1-13. https://doi.org/10.1038/s41598-021-99432-4

We previously reported that growth promoter-induced skeletal muscle hypertrophy co-ordinately upregulated expression of genes associated with an integrated stress response (ISR), as well as potential ISR regulators. We therefore used Adeno-Associated... Read More about Effect of AAV-mediated overexpression of ATF5 and downstream targets of an integrated stress response in murine skeletal muscle.