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Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping (2023)
Journal Article
Hobson, P. J., Hardwicke, N. L., Davis, A., Smith, T. X., Morley, C., Packer, M., Holmes, N., Weil, M. A., Brookes, M. J., Bowtell, R., & Fromhold, M. (2023). Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping. IEEE Transactions on Instrumentation and Measurement, 72, Article 1005815. https://doi.org/10.1109/TIM.2023.3284138

Adaptable, low-cost, coils designed by carefully selecting the arrangements and geometries of simple primitive units are used to generate magnetic fields for diverse applications. These extend from magnetic resonance and fundamental physics experimen... Read More about Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping.

An examination of resting-state functional connectivity in patients with active Crohn's disease (2023)
Journal Article
Francis, S. T., Moran, G. W., Eldeghaidy, S., Radford, S., & Thapaliya, G. (2023). An examination of resting-state functional connectivity in patients with active Crohn's disease. Frontiers in Neuroscience, 17, Article 1265815. https://doi.org/10.3389/fnins.2023.1265815

Background: Alterations in resting state functional connectivity (rs-FC) in Crohn’s Disease (CD) have been documented in default mode network (DMN) and frontal parietal network (FPN) areas, visual, cerebellar, salience and attention resting-state-net... Read More about An examination of resting-state functional connectivity in patients with active Crohn's disease.

An examination of resting-state functional connectivity in patients with active Crohn’s disease (2023)
Journal Article
Thapaliya, G., Eldeghaidy, S., Radford, S. J., Francis, S. T., & Moran, G. W. (in press). An examination of resting-state functional connectivity in patients with active Crohn’s disease. Frontiers in Neuroscience, 17, Article 1265815. https://doi.org/10.3389/fnins.2023.1265815

Background: Alterations in resting state functional connectivity (rs-FC) in Crohn’s Disease (CD) have been documented in default mode network (DMN) and frontal parietal network (FPN) areas, visual, cerebellar, salience and attention resting-state-net... Read More about An examination of resting-state functional connectivity in patients with active Crohn’s disease.

Tri-axial rubidium and helium optically pumped magnetometers for on-scalp magnetoencephalography recording of interictal epileptiform discharges: a case study (2023)
Journal Article
Feys, O., Corvilain, P., Labyt, E., Mahmoudzadeh, M., Routier, L., Sculier, C., Holmes, N., Brookes, M., Goldman, S., Romain, R., Mitryukovskiy, S., Palacios-Laloy, A., Schwartz, D., Betrouni, N., Derambure, P., Wallois, F., Wens, V., & De Tiège, X. (2023). Tri-axial rubidium and helium optically pumped magnetometers for on-scalp magnetoencephalography recording of interictal epileptiform discharges: a case study. Frontiers in Neuroscience, 17, Article 1284262. https://doi.org/10.3389/fnins.2023.1284262

Cryogenic magnetoencephalography (MEG) enhances the presurgical assessment of refractory focal epilepsy (RFE). Optically pumped magnetometers (OPMs) are cryogen-free sensors that enable on-scalp MEG recordings. Here, we investigate the application of... Read More about Tri-axial rubidium and helium optically pumped magnetometers for on-scalp magnetoencephalography recording of interictal epileptiform discharges: a case study.

Multiparametric Renal Magnetic Resonance Imaging for Prediction and Annual Monitoring of the Progression of Chronic Kidney Disease over Two Years (2023)
Journal Article
Buchanan, C. E., Mahmoud, H., Cox, E. F., Prestwich, B. L., Noble, R. A., Selby, N. M., Taal, M. W., & Francis, S. T. (2023). Multiparametric Renal Magnetic Resonance Imaging for Prediction and Annual Monitoring of the Progression of Chronic Kidney Disease over Two Years. Journal of Clinical Medicine, 12(23), Article 7282. https://doi.org/10.3390/jcm12237282

Background: Multiparametric renal Magnetic Resonance Imaging (MRI) provides a non-invasive method to assess kidney structure and function, but longitudinal studies are limited. Methods: A total of 22 patients with CKD category G3-4 (estimated glomeru... Read More about Multiparametric Renal Magnetic Resonance Imaging for Prediction and Annual Monitoring of the Progression of Chronic Kidney Disease over Two Years.

Portable single-beam cesium zero-field magnetometer for magnetocardiography (2023)
Journal Article
Dawson, R., O'Dwyer, C., Mrozowski, M. S., Irwin, E., McGilligan, J. P., Burt, D. P., Hunter, D., Ingleby, S., Rea, M., Holmes, N., Brookes, M. J., Griffin, P. F., & Riis, E. (2023). Portable single-beam cesium zero-field magnetometer for magnetocardiography. Journal of Optical Microsystems, 3(4), Article 044501. https://doi.org/10.1117/1.jom.3.4.044501

Optically pumped magnetometers (OPMs) are becoming common in the realm of biomagnetic measurements. We discuss the development of a prototype zero-field cesium portable OPM and its miniaturized components. Zero-field sensors operate in a very low sta... Read More about Portable single-beam cesium zero-field magnetometer for magnetocardiography.

ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): ASL pipeline inventory (2023)
Journal Article
Fan, H., Mutsaerts, H. J. M. M., Anazodo, U., Arteaga, D., Baas, K. P. A., Buchanan, C., Camargo, A., Keil, V. C., Lin, Z., Lindner, T., Hirschler, L., Hu, J., Padrela, B. E., Taghvaei, M., Thomas, D. L., Dolui, S., & Petr, J. (2024). ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): ASL pipeline inventory. Magnetic Resonance in Medicine, 91(5), 1787-1802. https://doi.org/10.1002/mrm.29869

Purpose: To create an inventory of image processing pipelines of arterial spin labeling (ASL) and list their main features, and to evaluate the capability, flexibility, and ease of use of publicly available pipelines to guide novice ASL users in sele... Read More about ISMRM Open Science Initiative for Perfusion Imaging (OSIPI): ASL pipeline inventory.

Liver investigation: Testing marker utility in steatohepatitis (LITMUS): Assessment & validation of imaging modality performance across the NAFLD spectrum in a prospectively recruited cohort study (the LITMUS imaging study): Study protocol (2023)
Journal Article
Pavlides, M., Mózes, F. E., Akhtar, S., Wonders, K., Cobbold, J., Tunnicliffe, E. M., Allison, M., Godfrey, E. M., Aithal, G. P., Francis, S., Romero-Gomez, M., Castell, J., Fernandez-Lizaranzu, I., Aller, R., Sigüenza González, R., Agustin, S., Pericàs, J. M., Boursier, J., Aube, C., Ratziu, V., …Harrison, S. (2023). Liver investigation: Testing marker utility in steatohepatitis (LITMUS): Assessment & validation of imaging modality performance across the NAFLD spectrum in a prospectively recruited cohort study (the LITMUS imaging study): Study protocol. Contemporary Clinical Trials, 134, Article 107352. https://doi.org/10.1016/j.cct.2023.107352

Non-alcoholic fatty liver disease (NAFLD) is the liver manifestation of the metabolic syndrome with global prevalence reaching epidemic levels. Despite the high disease burden in the population only a small proportion of those with NAFLD will develop... Read More about Liver investigation: Testing marker utility in steatohepatitis (LITMUS): Assessment & validation of imaging modality performance across the NAFLD spectrum in a prospectively recruited cohort study (the LITMUS imaging study): Study protocol.

Unified Surface and Volumetric Inference on Functional Imaging Data (2023)
Presentation / Conference Contribution
Kirk, T. F., Craig, M. S., & Chappell, M. A. (2023, October). Unified Surface and Volumetric Inference on Functional Imaging Data. Presented at Medical Image Computing and Computer Assisted Intervention – MICCAI 2023, Vancouver, BC, Canada

Surface-based analysis methods for functional imaging data have been shown to offer substantial benefits for the study of the human cortex, namely in the localisation of functional areas and the establishment of inter-subject correspondence. A new ap... Read More about Unified Surface and Volumetric Inference on Functional Imaging Data.

A novel approach to monitor head movement inside an MR scanner using voltages induced in coils by time-varying gradients (2023)
Journal Article
Bhuiyan, E. H., Chowdhury, M. E., & Glover, P. M. (2023). A novel approach to monitor head movement inside an MR scanner using voltages induced in coils by time-varying gradients. IEEE Access, 11, 107004-107018. https://doi.org/10.1109/access.2023.3318171

To determine head pose within an MR scanner using measurements of gradient-induced voltage from a multiple coil. A practical implementation of this approach would involve measuring the position-sensitive voltages induced by the imaging gradients rath... Read More about A novel approach to monitor head movement inside an MR scanner using voltages induced in coils by time-varying gradients.

The impact of variations in subject geometry, respiration and coil repositioning on the specific absorption rate in parallel transmit abdominal imaging at 7 T (2023)
Journal Article
Doran, E., Naim, I., Bowtell, R., Gowland, P. A., Glover, P. M., & Bawden, S. (in press). The impact of variations in subject geometry, respiration and coil repositioning on the specific absorption rate in parallel transmit abdominal imaging at 7 T. NMR in Biomedicine, Article e5032. https://doi.org/10.1002/nbm.5032

Parallel transmit MRI at 7 T has increasingly been adopted in research projects and provides increased signal‐to‐noise ratios and novel contrasts. However, the interactions of fields in the body need to be carefully considered to ensure safe scanning... Read More about The impact of variations in subject geometry, respiration and coil repositioning on the specific absorption rate in parallel transmit abdominal imaging at 7 T.

Two-Dimensional Population Receptive Field Mapping of Human Primary Somatosensory Cortex (2023)
Journal Article
Asghar, M., Sanchez-Panchuelo, R., Schluppeck, D., & Francis, S. (2023). Two-Dimensional Population Receptive Field Mapping of Human Primary Somatosensory Cortex. Brain Topography, 36, 816-834. https://doi.org/10.1007/s10548-023-01000-8

Functional magnetic resonance imaging can provide detailed maps of how sensory space is mapped in the human brain. Here, we use a novel 16 stimulator setup (a 4 × 4 grid) to measure two-dimensional sensory maps of between and within-digit (D2–D4) spa... Read More about Two-Dimensional Population Receptive Field Mapping of Human Primary Somatosensory Cortex.

Spatial organisation of the mesoscale connectome: A feature influencing synchrony and metastability of network dynamics (2023)
Journal Article
Mackay, M., Huo, S., & Kaiser, M. (2023). Spatial organisation of the mesoscale connectome: A feature influencing synchrony and metastability of network dynamics. PLoS Computational Biology, 19(8), Article e1011349. https://doi.org/10.1371/journal.pcbi.1011349

Significant research has investigated synchronisation in brain networks, but the bulk of this work has explored the contribution of brain networks at the macroscale. Here we explore the effects of changing network topology on functional dynamics in s... Read More about Spatial organisation of the mesoscale connectome: A feature influencing synchrony and metastability of network dynamics.

Measuring chemical exchange saturation transfer exchange rates in the human brain using a particle swarm optimisation algorithm (2023)
Journal Article
Carradus, A. J., Bradley, J. M., Gowland, P. A., & Mougin, O. E. (2023). Measuring chemical exchange saturation transfer exchange rates in the human brain using a particle swarm optimisation algorithm. NMR in Biomedicine, 36(11), Article e5001. https://doi.org/10.1002/nbm.5001

The z‐spectrum contains many pools with different exchange rates and T 2 values, which can make it difficult to interpret in vivo data and complicates the design of experiments aimed at providing sensitivity to one pool. This work aims to characteris... Read More about Measuring chemical exchange saturation transfer exchange rates in the human brain using a particle swarm optimisation algorithm.

Randomised trial comparing standard versus thermocontrolled haemodialysis using intradialytic cardiac, brain and renal magnetic resonance imaging (2023)
Journal Article
Gullapudi, V. R. L., Cox, E. F., Buchanan, C. E., Canaud, B., White, K., Taal, M. W., Selby, N. M., & Francis, S. T. (2024). Randomised trial comparing standard versus thermocontrolled haemodialysis using intradialytic cardiac, brain and renal magnetic resonance imaging. Nephrology Dialysis Transplantation, 39(2), 233–241. https://doi.org/10.1093/ndt/gfad150

Background
Ischaemic end-organ damage during haemodialysis (HD) is a significant problem that may be ameliorated by intradialytic cooling. A randomised trial was performed to compare standard HD (SHD; dialysate temperature 37°C) and programmed cooli... Read More about Randomised trial comparing standard versus thermocontrolled haemodialysis using intradialytic cardiac, brain and renal magnetic resonance imaging.

Benchtop magnetic shielding for benchmarking atomic magnetometers (2023)
Journal Article
Hobson, P. J., Holmes, N., Patel, P., Styles, B., Chalmers, J., Morley, C., Davis, A., Packer, M., Smith, T. X., Raudonyte, S., Holmes, D., Harrison, R., Woolger, D., Sims, D., Brookes, M. J., Bowtell, R., & Fromhold, M. (2023). Benchtop magnetic shielding for benchmarking atomic magnetometers. IEEE Transactions on Instrumentation and Measurement, 72, Article 6007309. https://doi.org/10.1109/tim.2023.3293540

Here, a benchtop hybrid magnetic shield containing four mumetal cylinders and nine internal flexible printed circuit boards is designed, constructed, tested, and operated. The shield is designed specifically as a test-bed for building and operating u... Read More about Benchtop magnetic shielding for benchmarking atomic magnetometers.

An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts (2023)
Journal Article
Holmes, N., Bowtell, R., Brookes, M. J., & Taulu, S. (2023). An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts. Sensors, 23(14), Article 6537. https://doi.org/10.3390/s23146537

The signal space separation (SSS) method is routinely employed in the analysis of multichannel magnetic field recordings (such as magnetoencephalography (MEG) data). In the SSS method, signal vectors are posed as a multipole expansion of the magnetic... Read More about An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts.