On the control of secondary carbanion structure utilising ligand effects during directed metallation
(2012)
Journal Article
Wheatley, A. E., Clayden, J., Hillier, I. H., Campbell Smith, A., Vincent, M. A., Taylor, L. J., & Haywood, J. (2012). On the control of secondary carbanion structure utilising ligand effects during directed metallation. Beilstein Journal of Organic Chemistry, 8, 50-60. https://doi.org/10.3762/bjoc.8.5
N,N-Diisopropyl-2-propylbenzamide 6-H undergoes lateral deprotonation by t-BuLi in the presence of the Lewis base PMDTA (N,N,N′,N″,N″-pentamethyldiethylenetriamine) to give a benzyllithium 6-Lil·PMDTA that incorporates a trigonal planar secondary car... Read More about On the control of secondary carbanion structure utilising ligand effects during directed metallation.