Neuromelanin-MRI to Quantify and Track Nigral Depigmentation in Parkinson's Disease: A Multicenter Longitudinal Study Using Template-Based Standardized Analysis
(2022)
Journal Article
Xing, Y., Sapuan, A. H., Martín-Bastida, A., Naidu, S., Tench, C., Evans, J., Sare, G., Schwarz, S. T., Al-bachari, S., Parkes, L. M., Kanavou, S., Raw, J., Silverdale, M., Bajaj, N., Pavese, N., Burn, D., Piccini, P., Grosset, D. G., & Auer, D. P. (2022). Neuromelanin-MRI to Quantify and Track Nigral Depigmentation in Parkinson's Disease: A Multicenter Longitudinal Study Using Template-Based Standardized Analysis. Movement Disorders, 37(5), 1028-1039. https://doi.org/10.1002/mds.28934
Background: Clinical diagnosis and monitoring of Parkinson's disease (PD) remain challenging because of the lack of an established biomarker. Neuromelanin-magnetic resonance imaging (NM-MRI) is an emerging biomarker of nigral depigmentation indexing... Read More about Neuromelanin-MRI to Quantify and Track Nigral Depigmentation in Parkinson's Disease: A Multicenter Longitudinal Study Using Template-Based Standardized Analysis.