Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: Genetic subtype defines antigenic but not neutralization serotype
(2011)
Journal Article
Tarr, A. W., Urbanowicz, R. A., Hamed, M. R., Albecka, A., McClure, C. P., Brown, R. J., …Ball, J. K. (2011). Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: Genetic subtype defines antigenic but not neutralization serotype. Journal of Virology, 85(9), 4246-4257. https://doi.org/10.1128/JVI.01332-10
Neutralizing antibodies have a role in controlling hepatitis C virus (HCV) infection. A successful vaccine will need to elicit potently neutralizing antibodies that are capable of preventing the infection of genetically diverse viral isolates. Howeve... Read More about Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: Genetic subtype defines antigenic but not neutralization serotype.