Use of short-tandem repeat (STR) fingerprinting to validate sample origins in hepatitis C virus molecular epidemiology studies

Edwards, Victoria C.; McClure, Patrick; Brown, Richard J.P.; Thompson, Emma; Irving, William L.; Ball, Jonathan K.

doi:10.1099/vir.0.057828-0

All Outputs (5)

Serum autoantibody measurement for the detection of hepatocellular carcinoma (2014)
Journal Article

Background: Individuals with liver disease, and especially those with Hepatitis B or C, are at an increased risk of developing hepatocellular carcinoma (HCC) which is the third most common cause of cancer-related death worldwide. Inadequate screening... Read More about Serum autoantibody measurement for the detection of hepatocellular carcinoma.

Recombinant Human L-Ficolin Directly Neutralizes Hepatitis C Virus Entry (2014)
Journal Article

L-ficolin is a soluble pattern recognition molecule expressed by the liver that contributes to innate immune defense against microorganisms. It is well described that binding of L-ficolin to specific pathogen-associated molecular patterns activates t... Read More about Recombinant Human L-Ficolin Directly Neutralizes Hepatitis C Virus Entry.

Multiplex protein analysis to determine fibrosis stage and progression in patients with chronic hepatitis C. (2014)
Journal Article

Background & Aims: Noninvasive tests cannot differentiate between adjacent stages of fibrosis, which limits assessment of disease progression and regression during therapy. We investigated whether levels of cytokines and extracellular matrix proteins... Read More about Multiplex protein analysis to determine fibrosis stage and progression in patients with chronic hepatitis C..

Using surveillance data to determine treatment rates and outcomes for patients with chronic hepatitis C virus infection (2014)
Journal Article

The aim of this work was to develop and validate an algorithm to monitor rates of, and response to, treatment of patients infected with hepatitis C virus (HCV) across England using routine laboratory HCV RNA testing data. HCV testing activity between... Read More about Using surveillance data to determine treatment rates and outcomes for patients with chronic hepatitis C virus infection.

Use of short-tandem repeat (STR) fingerprinting to validate sample origins in hepatitis C virus molecular epidemiology studies (2014)
Journal Article

Sequence analysis is used to define the molecular epidemiology and evolution of the hepatitis C virus. Whilst most studies have shown that individual patients harbour viruses that are derived from a limited number of highly related strains, some rece... Read More about Use of short-tandem repeat (STR) fingerprinting to validate sample origins in hepatitis C virus molecular epidemiology studies.