Differential activation of killer cells in the circulation and the lung: a study of current smoking status and chronic obstructive pulmonary disease (COPD)

Wang, Jia; Urbanowicz, Richard A.; Tighe, Patrick J.; Todd, Ian; Corne, Jonathan M.; Fairclough, Lucy C.

doi:10.1371/journal.pone.0058556

All Outputs (5)

Urinary extracellular vesicle protein profiling and endogenous lithium clearance support excessive renal sodium wasting and water reabsorption in thiazide induced hyponatremia (2018)
Journal Article

Introduction Thiazide diuretics are amongst the most widely used anti-hypertensive medicines worldwide. Thiazide-Induced Hyponatremia (TIH) is one of their most clinically significant adverse effects. A priori TIH must result from excessive saliur... Read More about Urinary extracellular vesicle protein profiling and endogenous lithium clearance support excessive renal sodium wasting and water reabsorption in thiazide induced hyponatremia.

Clinical and molecular features of thiazide-induced hyponatremia (2018)
Journal Article

Hypertension affects more than 30% of the world’s adult population and thiazide (and thiazide-like) diuretics are amongst the most widely used, effective and least costly treatments available, with all-cause mortality benefits equivalent to ACE inhib... Read More about Clinical and molecular features of thiazide-induced hyponatremia.

Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia (2017)
Journal Article

Thiazide diuretics are among the most widely used treatments for hypertension, but thiazide-induced hyponatremia (TIH), a clinically significant adverse effect, is poorly understood. Here, we have studied the phenotypic and genetic characteristics of... Read More about Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia.

Hippocampus and two-way active avoidance conditioning: Contrasting effects of cytotoxic lesion and temporary inactivation (2015)
Journal Article

© 2015 Wiley Periodicals, Inc. Hippocampal lesions tend to facilitate two-way active avoidance (2WAA) conditioning, where rats learn to cross to the opposite side of a conditioning chamber to avoid a tone-signaled footshock. This classical finding ha... Read More about Hippocampus and two-way active avoidance conditioning: Contrasting effects of cytotoxic lesion and temporary inactivation.

Differential activation of killer cells in the circulation and the lung: a study of current smoking status and chronic obstructive pulmonary disease (COPD) (2013)
Journal Article

Background:CD8+ T-lymphocytes, natural killer T-like cells (NKT-like cells, CD56+CD3+) and natural killer cells (NK cells, CD56+CD3?) are the three main classes of human killer cells and they are implicated in the pathogenesis of chronic obstructive... Read More about Differential activation of killer cells in the circulation and the lung: a study of current smoking status and chronic obstructive pulmonary disease (COPD).