All Outputs (155)

The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012 (2014)
Journal Article
Rees, F., Doherty, M., Grainge, M. J., Davenport, G., Lanyon, P., & Zhang, W. (in press). The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012. Annals of the Rheumatic Diseases, 75(1), https://doi.org/10.1136/annrheumdis-2014-206334

Objectives: To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999–2012.

Methods: A retrospective cohort study using the Clinical Practice Research Datalink (CPRD). The incidence was calculate... Read More about The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012.

Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study. (2014)
Journal Article
McWilliams, D. F., Muthuri, S., Muir, K. R., Maciewicz, R. A., Zhang, W., & Doherty, M. (2014). Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study. BMC Musculoskeletal Disorders, 15(1), https://doi.org/10.1186/1471-2474-15-308

Background: Biomechanical factors may play a role in osteoarthritis (OA) development and progression. Previous biomechanical studies have indicated that types of footwear may modulate forces across the knee joint, and high heeled womens' shoes in par... Read More about Self-reported adult footwear and the risks of lower limb osteoarthritis: the GOAL case control study..

The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study (2014)
Journal Article
Doherty, S., Zhang, W., Maciewicz, R., Doherty, M., Muir, K., Abhishek, A., & Valdes, A. M. (2014). The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study. Arthritis Research and Therapy, 16(1), Article R25. https://doi.org/10.1186/ar4453

Introduction
Chondrocalcinosis (CC) most commonly results from calcium pyrophosphate crystal deposition (CPPD). The objective of this study is to examine the association between candidate single-nucleotide polymorphisms (SNPs) and radiographic CC.... Read More about The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study.

Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial (2014)
Journal Article
Mu, R., Bao, C. D., Chen, Z. W., Zheng, Y., Wang, G. C., Zhao, D. B., Hu, S. X., Li, Y. J., Shao, Z. W., Zhang, Z. Y., Xiao, W. G., Zhang, W., & Li, Z. G. (2016). Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial. Clinical Rheumatology, 35(1), 165-173. https://doi.org/10.1007/s10067-014-2701-4

© 2014, Clinical Rheumatology. This study is aimed at comparing the efficacy and safety of loxoprofen sodium hydrogel patch (LX-P) with loxoprofen sodium tablet (LX-T) in patients with knee osteoarthritis (OA). One hundred sixty-nine patients were en... Read More about Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial.

Ultrasound detected synovial change and pain response following intra-articular injection of corticosteroid and a placebo in symptomatic osteoarthritic knees: a pilot study (2014)
Journal Article
Hall, M. C., Doherty, S., Courtney, P., Latief, K., Zhang, W., & Doherty, M. (in press). Ultrasound detected synovial change and pain response following intra-articular injection of corticosteroid and a placebo in symptomatic osteoarthritic knees: a pilot study. Annals of the Rheumatic Diseases, 73(8), https://doi.org/10.1136/annrheumdis-2014-205206

Knee joint stiffness and its relationship with severity of radiographic osteoarthritis, pain and self-reported stiffness (2014)
Journal Article
Hall, M., Doherty, S., Zhang, W., & Doherty, M. (2014). Knee joint stiffness and its relationship with severity of radiographic osteoarthritis, pain and self-reported stiffness. Osteoarthritis and Cartilage, 22(Supplement), S92. https://doi.org/10.1016/j.joca.2014.02.178

Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials: Impact of Exercise Type and Dose in Knee Osteoarthritis (2014)
Journal Article
Juhl, C., Christensen, R., Roos, E. M., Zhang, W., & Lund, H. (2014). Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials: Impact of Exercise Type and Dose in Knee Osteoarthritis. Arthritis and Rheumatology, 66(3), 622-636. https://doi.org/10.1002/art.38290

Objective: To identify the optimal exercise program, characterized by type and intensity of exercise, length of program, duration of individual supervised sessions, and number of sessions per week, for reducing pain and patient-reported disability in... Read More about Impact of Exercise Type and Dose on Pain and Disability in Knee Osteoarthritis: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials: Impact of Exercise Type and Dose in Knee Osteoarthritis.

Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study (2014)
Journal Article
Kuo, C. F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2015). Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study. Annals of the Rheumatic Diseases, 74(4), 661-667. https://doi.org/10.1136/annrheumdis-2013-204463

Objectives: To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012. Methods: We used the Clinical Practice Research Datalink to estimate the prevalence and incidenc... Read More about Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study.

Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan (2013)
Journal Article
Kuo, C.-F., Grainge, M. J., See, L.-C., Yu, K.-H., Luo, S.-F., Valdes, A. M., Zhang, W., & Doherty, M. (2015). Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan. Annals of the Rheumatic Diseases, 74(2), 369-374. https://doi.org/10.1136/annrheumdis-2013-204067

© 2015, BMJ Publishing Group. All rights reserved. Objective: To examine familial aggregation of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population. Methods: Using data from the Nati... Read More about Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan.

The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study (2013)
Journal Article
Panoutsopoulou, K., Metrustry, S., Doherty, S. A., Laslett, L. L., Maciewicz, R. A., Hart, D. J., Zhang, W., Muir, K. R., Wheeler, M., Cooper, C., Spector, T. D., Cicuttini, F. M., Jones, G., Arden, N. K., Doherty, M., Zeggini, E., & Valdes, A. M. (2014). The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study. Annals of the Rheumatic Diseases, 73(12), 2082-2086. https://doi.org/10.1136/annrheumdis-2013-203772

© 2015, BMJ Publishing Group. All rights reserved. Objective: Variation in the fat mass and obesity-associated (FTO) gene influences susceptibility to obesity. A variant in the FTO gene has been implicated in genetic risk to osteoarthritis (OA). We e... Read More about The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study.

Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study (2013)
Journal Article
Doherty, S., Doherty, M., Maciewicz, R., Abhishek, A., Muir, K., & Zhang, W. (2014). Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study. Annals of the Rheumatic Diseases, 73(11), 1997-2002. https://doi.org/10.1136/annrheumdis-2013-203400

Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis (2013)
Journal Article
Muthuri, S. G., Doherty, S., Zhang, W., Maciewicz, R. A., Muir, K. R., & Doherty, M. (2013). Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis. Arthritis Research and Therapy, 15(2), Article R52. https://doi.org/10.1186/ar4214

Introduction: The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFβ1 polymorphisms in knee and hip osteoarthritis (OA).
Methods: We conducted a case-control study of Caucasian me... Read More about Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis.

Chondrocalcinosis is common in the absence of knee involvement (2012)
Journal Article
Abhishek, A., Doherty, S., Maciewicz, R., Muir, K., Zhang, W., & Doherty, M. (2012). Chondrocalcinosis is common in the absence of knee involvement. Arthritis Research and Therapy, 14(5), Article 5. https://doi.org/10.1186/ar4043

Introduction: We aimed to describe the distribution of radiographic chondrocalcinosis (CC) and to examine
whether metacarpophalangeal joint (MCPJ) calcification and CC at other joints occurs in the absence of knee
involvement.

Methods: This was... Read More about Chondrocalcinosis is common in the absence of knee involvement.

Quantitative sensory testing in painful osteoarthritis: A systematic review and meta-analysis (2012)
Journal Article
Suokas, A. K., Walsh, D. A., McWilliams, D. F., Condon, L., Moreton, B., Wylde, V., Arendt-Nielsen, L., & Zhang, W. (2012). Quantitative sensory testing in painful osteoarthritis: A systematic review and meta-analysis. Osteoarthritis and Cartilage, 20(10), 1075-1085. https://doi.org/10.1016/j.joca.2012.06.009

Objective: To systematically review the use of Quantitative sensory testing (QST) in pain characterisation (phenotyping) in Osteoarthritis (OA). Methods: Six bibliographic databases (Medline, Embase, Amed, Cinahl, PubMed, Web of Science) were searche... Read More about Quantitative sensory testing in painful osteoarthritis: A systematic review and meta-analysis.

Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study (2012)
Journal Article
McWilliams, D. F., Zhang, W., Mansell, J. S., Kiely, P. D., Young, A., & Walsh, D. A. (2012). Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study. Arthritis Care and Research, 64(10), https://doi.org/10.1002/acr.21723

Objective: To investigate possible predictors for lack of pain improvement after 1 year of treatment for early rheumatoid arthritis (RA).

Methods: The Early Rheumatoid Arthritis Network (ERAN) database was used for analysis of baseline and 1-year... Read More about Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study.