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All Outputs (95)

Effect of allopurinol on all-cause mortality in adults with incident gout: propensity score–matched landmark analysis (2015)
Journal Article
Kuo, C.-F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2015). Effect of allopurinol on all-cause mortality in adults with incident gout: propensity score–matched landmark analysis. Rheumatology, 54(12), https://doi.org/10.1093/rheumatology/kev246

Objective: To examine the association between allopurinol use and all-cause mortality for patients with incident gout.

Methods: We compared all-cause mortality in incident gout patients who received allopurinol for at least 6 months within the exp... Read More about Effect of allopurinol on all-cause mortality in adults with incident gout: propensity score–matched landmark analysis.

Global epidemiology of gout: prevalence, incidence and risk factors (2015)
Journal Article
Kuo, C.-F., Grainge, M. J., Zhang, W., & Doherty, M. (2015). Global epidemiology of gout: prevalence, incidence and risk factors. Nature Reviews Rheumatology, 11(11), 649-662. https://doi.org/10.1038/nrrheum.2015.91

Gout is a crystal-deposition disease that results from chronic elevation of uric acid levels above the saturation point for monosodium urate (MSU) crystal formation. Initial presentation is mainly severely painful episodes of peripheral joint synovit... Read More about Global epidemiology of gout: prevalence, incidence and risk factors.

Familial risk of Sjögren's syndrome and co-aggregation of autoimmune diseases in affected families: a nationwide population study (2015)
Journal Article
Kuo, C.-F., Grainge, M. J., Valdes, A. M., See, L.-C., Luo, S.-F., Yu, K.-H., Zhang, W., & Doherty, M. (2015). Familial risk of Sjögren's syndrome and co-aggregation of autoimmune diseases in affected families: a nationwide population study. Arthritis and Rheumatology, 67(7), 1904-1912. https://doi.org/10.1002/art.39127

Objective: To investigate familial aggregation of Sjögren's syndrome (SS) and the relative risks (RRs) of other autoimmune disease in relatives of patients with SS.
Methods: We identified 23,658,577 beneficiaries enrolled in the Taiwan National Hea... Read More about Familial risk of Sjögren's syndrome and co-aggregation of autoimmune diseases in affected families: a nationwide population study.

Epidemiology and management of gout in Taiwan: a nationwide population study (2015)
Journal Article
Kuo, C.-F., Grainge, M. J., See, L.-C., Yu, K.-H., Luo, S.-F., Zhang, W., & Doherty, M. (in press). Epidemiology and management of gout in Taiwan: a nationwide population study. Arthritis Research and Therapy, 17(1), https://doi.org/10.1186/s13075-015-0522-8

INTRODUCTION: Gout is the most common inflammatory arthritis worldwide and is the only type of chronic arthritis that potentially can be ‘cured’. However, data on gout incidence, prevalence and management, assessed at multiple time points in the same... Read More about Epidemiology and management of gout in Taiwan: a nationwide population study.

Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England (2014)
Journal Article
Kuo, C.-F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2014). Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England. Journal of the American Medical Association, 312(24), https://doi.org/10.1001/jama.2014.14484

Gout is caused by urate crystal deposition secondary to persistent hyperuricemia. Current guidelines recommend urate-lowering treatment to prevent crystal deposition and encourage crystal dissolution for patients with more severe gout or concomitant... Read More about Eligibility for and prescription of urate-lowering treatment in patients with incident gout in England.

The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012 (2014)
Journal Article
Rees, F., Doherty, M., Grainge, M. J., Davenport, G., Lanyon, P., & Zhang, W. (in press). The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012. Annals of the Rheumatic Diseases, 75(1), https://doi.org/10.1136/annrheumdis-2014-206334

Objectives: To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999–2012.

Methods: A retrospective cohort study using the Clinical Practice Research Datalink (CPRD). The incidence was calculate... Read More about The incidence and prevalence of systemic lupus erythematosus in the UK, 1999–2012.

The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study (2014)
Journal Article
Doherty, S., Zhang, W., Maciewicz, R., Doherty, M., Muir, K., Abhishek, A., & Valdes, A. M. (2014). The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study. Arthritis Research and Therapy, 16(1), Article R25. https://doi.org/10.1186/ar4453

Introduction
Chondrocalcinosis (CC) most commonly results from calcium pyrophosphate crystal deposition (CPPD). The objective of this study is to examine the association between candidate single-nucleotide polymorphisms (SNPs) and radiographic CC.... Read More about The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case–control study.

Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study (2014)
Journal Article
Kuo, C. F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2015). Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study. Annals of the Rheumatic Diseases, 74(4), 661-667. https://doi.org/10.1136/annrheumdis-2013-204463

Objectives: To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012. Methods: We used the Clinical Practice Research Datalink to estimate the prevalence and incidenc... Read More about Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study.

Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan (2013)
Journal Article
Kuo, C.-F., Grainge, M. J., See, L.-C., Yu, K.-H., Luo, S.-F., Valdes, A. M., Zhang, W., & Doherty, M. (2015). Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan. Annals of the Rheumatic Diseases, 74(2), 369-374. https://doi.org/10.1136/annrheumdis-2013-204067

© 2015, BMJ Publishing Group. All rights reserved. Objective: To examine familial aggregation of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population. Methods: Using data from the Nati... Read More about Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan.

Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study (2013)
Journal Article
Doherty, S., Doherty, M., Maciewicz, R., Abhishek, A., Muir, K., & Zhang, W. (2014). Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study. Annals of the Rheumatic Diseases, 73(11), 1997-2002. https://doi.org/10.1136/annrheumdis-2013-203400

Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis (2013)
Journal Article
Muthuri, S. G., Doherty, S., Zhang, W., Maciewicz, R. A., Muir, K. R., & Doherty, M. (2013). Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis. Arthritis Research and Therapy, 15(2), Article R52. https://doi.org/10.1186/ar4214

Introduction: The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFβ1 polymorphisms in knee and hip osteoarthritis (OA).
Methods: We conducted a case-control study of Caucasian me... Read More about Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis.

Quantitative sensory testing in painful osteoarthritis: A systematic review and meta-analysis (2012)
Journal Article
Suokas, A. K., Walsh, D. A., McWilliams, D. F., Condon, L., Moreton, B., Wylde, V., Arendt-Nielsen, L., & Zhang, W. (2012). Quantitative sensory testing in painful osteoarthritis: A systematic review and meta-analysis. Osteoarthritis and Cartilage, 20(10), 1075-1085. https://doi.org/10.1016/j.joca.2012.06.009

Objective: To systematically review the use of Quantitative sensory testing (QST) in pain characterisation (phenotyping) in Osteoarthritis (OA). Methods: Six bibliographic databases (Medline, Embase, Amed, Cinahl, PubMed, Web of Science) were searche... Read More about Quantitative sensory testing in painful osteoarthritis: A systematic review and meta-analysis.

Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study (2012)
Journal Article
McWilliams, D. F., Zhang, W., Mansell, J. S., Kiely, P. D., Young, A., & Walsh, D. A. (2012). Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study. Arthritis Care and Research, 64(10), https://doi.org/10.1002/acr.21723

Objective: To investigate possible predictors for lack of pain improvement after 1 year of treatment for early rheumatoid arthritis (RA).

Methods: The Early Rheumatoid Arthritis Network (ERAN) database was used for analysis of baseline and 1-year... Read More about Predictors of change in bodily pain in early rheumatoid arthritis: an inception cohort study.