All Outputs (93)

Comorbidities in Osteoarthritis: a systematic review and meta-analysis of observational studies (2020)
Journal Article
Swain, S., Sarmanova, A., Coupland, C., Doherty, M., & Zhang, W. (2020). Comorbidities in Osteoarthritis: a systematic review and meta-analysis of observational studies. Arthritis Care and Research, 72(7), 991-1000. https://doi.org/10.1002/acr.24008

Objectives

Osteoarthritis (OA) is a common chronic condition in older people but its association with other chronic conditions is largely unknown. This study aimed to systematically review the literature on comorbidities in people with OA compared... Read More about Comorbidities in Osteoarthritis: a systematic review and meta-analysis of observational studies.

Pain distant from the index site and sensitization in people with knee pain and low back pain (2020)
Presentation / Conference Contribution
Akin-Akinyosoye, K., Georgopoulos, V., Frowd, N., Swaithes, L., Stocks, J., Fernandes, G. S., Valdes, A., McWilliams, D., Zhang, W., Doherty, M., Ferguson, E., & Walsh, D. (2020, April). Pain distant from the index site and sensitization in people with knee pain and low back pain. Presented at OARSI 2020 World Congress, Vienna, Austria

Mediators of the predictive relationship between a self-report measure of central mechanisms and future knee pain outcomes in the knee pain in the community (KPIC) cohort (2020)
Presentation / Conference Contribution
Matthews, R., Akin-Akinyosoye, K., Frowd, N., Swaithes, L., Stocks, J., Sarmanova, A., Fernandes, G. S., Valdes, A., McWilliams, D. F., Zhang, W., Doherty, M., Ferguson, E., & Walsh, D. A. (2020, April). Mediators of the predictive relationship between a self-report measure of central mechanisms and future knee pain outcomes in the knee pain in the community (KPIC) cohort. Presented at OARSI 2020 World Congress, Vienna, Austria

Predicting response to topical non-steroidal anti-inflammatory drugs in osteoarthritis: an individual patient data meta-analysis of randomized controlled trials (2020)
Journal Article
Persson, M. S., Stocks, J., Varadi, G., Hashempur, M. H., van Middelkoop, M., Bierma-Zeinstra, S., Walsh, D. A., Doherty, M., & Zhang, W. (2020). Predicting response to topical non-steroidal anti-inflammatory drugs in osteoarthritis: an individual patient data meta-analysis of randomized controlled trials. Rheumatology, 59(9), 2207-2216. https://doi.org/10.1093/rheumatology/keaa113

© The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology.

OBJECTIVES: To identify predictors of the specific (difference between treatment and placebo) and overall (change from baseline in treat... Read More about Predicting response to topical non-steroidal anti-inflammatory drugs in osteoarthritis: an individual patient data meta-analysis of randomized controlled trials.

Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD) (2020)
Journal Article
Swain, S., Sarmanova, A., Mallen, C., Kuo, C. F., Coupland, C., Doherty, M., & Zhang, W. (2020). Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD). Osteoarthritis and Cartilage, 28(6), 792-801. https://doi.org/10.1016/j.joca.2020.03.004

© 2020 The Authors Objective: This study aimed to explore the incidence and prevalence of OA in the UK in 2017 and their trends from 1997 to 2017 using a large nationally representative primary care database. Design: The UK Clinical Practice Research... Read More about Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD).

Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study (2020)
Journal Article
Sarmanova, A., Doherty, M., Kuo, C., Wei, J., Abhishek, A., Mallen, C., Zeng, C., Wang, Y., Lei, G., & Zhang, W. (2020). Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study. Rheumatology, 59(10), 2898-2907. https://doi.org/10.1093/rheumatology/keaa044

© The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com. OBJECTIVE: Statins are reported to have a potential benefi... Read More about Statin use and risk of joint replacement due to osteoarthritis and rheumatoid arthritis: a propensity-score matched longitudinal cohort study.

Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI (2020)
Journal Article
Iwabuchi, S. J., Xing, Y., Cottam, W. J., Drabek, M. M., Tadjibaev, A., Fernandes, G. S., Petersen, K. K., Arendt-Nielsen, L., Graven-Nielsen, T., Valdes, A. M., Zhang, W., Doherty, M., Walsh, D., & Auer, D. P. (2020). Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI. PAIN, 161(6), 1255-1263. https://doi.org/10.1097/j.pain.0000000000001829

Chronic musculoskeletal pain is a common problem globally. Current evidence suggests that maladapted central pain pathways are associated with pain chronicity, for example, in postoperative pain after knee replacement. Other factors such as low mood,... Read More about Brain perfusion patterns are altered in chronic knee pain: a spatial covariance analysis of arterial spin labelling MRI.

Intra-articular Injection Administration in UK Ex-professional Footballers During Their Playing Careers and the Association with Post-career Knee Osteoarthritis (2020)
Journal Article
Fernandes, G. S., Parekh, S. M., Moses, J. P., Fuller, C. W., Scammell, B. E., Batt, M. E., Zhang, W., & Doherty, M. (2020). Intra-articular Injection Administration in UK Ex-professional Footballers During Their Playing Careers and the Association with Post-career Knee Osteoarthritis. Sports Medicine, 50, 1039–1046. https://doi.org/10.1007/s40279-019-01255-x

© 2020, The Author(s). Background: The long-term risk from knee intra-articular (KIA) injections in professional athletes such as ex-footballers remains unknown. The use of KIA injections is controversial and remains anecdotally prolific as it is per... Read More about Intra-articular Injection Administration in UK Ex-professional Footballers During Their Playing Careers and the Association with Post-career Knee Osteoarthritis.

Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort (2019)
Journal Article
Akin-Akinyosoye, K., Sarmanova, A., Fernandes, G., Frowd, N., Swaithes, L., Stocks, J., Valdes, A., Mcwilliams, D. F., Zhang, W., Doherty, M., Ferguson, E., & Walsh, D. A. (2020). Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort. Osteoarthritis and Cartilage, 28(2), 173-181. https://doi.org/10.1016/j.joca.2019.11.004

Objectives

We investigated whether baseline scores for a self-report trait linked to central mechanisms predict 1 year pain outcomes in the Knee Pain in the Community cohort.

Method

1471 participants reported knee pain at baseline and respon... Read More about Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort.

Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort (2019)
Journal Article
Akin-Akinyosoye, K., Sarmanova, A., Fernandes, G. S., Frowd, N., Swaithes, L., Stocks, J., Valdes, A., McWilliams, D. F., Zhang, W., Doherty, M., Ferguson, E., & Walsh, D. A. (2020). Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort. Osteoarthritis and Cartilage, 28(2), 173-181. https://doi.org/10.1016/j.joca.2019.11.004

© 2019 The Authors Objectives: We investigated whether baseline scores for a self-report trait linked to central mechanisms predict 1 year pain outcomes in the Knee Pain in the Community cohort. METHOD: 1471 participants reported knee pain at baselin... Read More about Baseline self-report ‘central mechanisms’ trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort.

The powerful placebo effect in osteoarthritis (2019)
Journal Article
Zhang, W. (2019). The powerful placebo effect in osteoarthritis. Clinical and Experimental Rheumatology, 37(5), S118-S123

Osteoarthritis (OA) is the most common form of arthritis. Pain and its related function and stiffness are currently the major symptoms and primary outcomes for treatment. However, the treatment in the past has been primarily targeting on the peripher... Read More about The powerful placebo effect in osteoarthritis.

Depressive symptoms and the general health of retired professional footballers compared with the general population in the UK: a case–control study (2019)
Journal Article
Fernandes, G. S., Parekh, S. M., Moses, J., Fuller, C. W., Scammell, B., Batt, M. E., Zhang, W., & Doherty, M. (2019). Depressive symptoms and the general health of retired professional footballers compared with the general population in the UK: a case–control study. BMJ Open, 9(9), Article e030056. https://doi.org/10.1136/bmjopen-2019-030056

The effectiveness of treatments for Kashin–Beck disease: a systematic review and network meta-analysis (2019)
Journal Article
Zou, K., Hu, J., Zhou, Q., Su, J., Dong, B., & Zhang, W. (2019). The effectiveness of treatments for Kashin–Beck disease: a systematic review and network meta-analysis. Clinical Rheumatology, 38(12), 3595-3607. https://doi.org/10.1007/s10067-019-04704-0

Objectives: This study aims to evaluate the efficacy of treatments for Kashin–Beck disease (KBD). Method: We searched PubMed, Cochrane Central Register of Controlled Trials, Embase, Web of Science, SinoMed, Chinese National Knowledge Infrastructure,... Read More about The effectiveness of treatments for Kashin–Beck disease: a systematic review and network meta-analysis.

Do β-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population?: A primary-care based prospective cohort study using the Clinical Practice Research Datalink (2019)
Journal Article
Nakafero, G., Grainge, M., Valdes, A., Townsend, N., Mallen, C., Zhang, W., Doherty, M., Mamas, M., & Abhishek, A. (2019). Do β-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population?: A primary-care based prospective cohort study using the Clinical Practice Research Datalink. BMJ Open, 9(8), Article e032050. https://doi.org/10.1136/bmjopen-2019-032050

© Author(s) (or their employer(s)) 2019. Introduction: To investigate if β-adrenoreceptor blocking drug (β-blocker) prescription reduces the risk of knee or hip osteoarthritis, total joint replacement and analgesic prescription. Setting: Primary care... Read More about Do β-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population?: A primary-care based prospective cohort study using the Clinical Practice Research Datalink.

Predictors of placebo response to local (intra-articular) therapy in osteoarthritis: An individual patient data meta-analysis protocol (2019)
Journal Article
Yu, S. P. C., Ferreira, M. L., Van Middelkoop, M., Bierma-Zeinstra, S. M., Zhang, W., Deveza, L. A., & Hunter, D. J. (2019). Predictors of placebo response to local (intra-articular) therapy in osteoarthritis: An individual patient data meta-analysis protocol. BMJ Open, 9(5), 1-6. https://doi.org/10.1136/bmjopen-2018-027372

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Osteoarthritis (OA) is a highly prevalent and disabling condition with limited safe and effecti... Read More about Predictors of placebo response to local (intra-articular) therapy in osteoarthritis: An individual patient data meta-analysis protocol.

Efficacy and potential determinants of exercise therapy in knee and hip osteoarthritis: a systematic review and meta-analysis (2019)
Journal Article
Goh, S.-L., Persson, M. S., Stocks, J., Hou, Y., Lin, J., Hall, M. C., Doherty, M., & Zhang, W. (2019). Efficacy and potential determinants of exercise therapy in knee and hip osteoarthritis: a systematic review and meta-analysis. Annals of Physical and Rehabilitation Medicine, 62(5), 356-365. https://doi.org/10.1016/j.rehab.2019.04.006

Background. Exercise is an effective treatment for osteoarthritis. However, the effect may vary from one patient (or study) to another.

Objective. To evaluate the efficacy of exercise and its potential determinants for pain, function, performance,... Read More about Efficacy and potential determinants of exercise therapy in knee and hip osteoarthritis: a systematic review and meta-analysis.

Identifying predictors of placebo response in osteoarthritis clinical trials of three agents with different routes of delivery: a meta-analysis using individual patient data (2019)
Presentation / Conference Contribution
Stocks, J., Persson, M., van Middelkoop, M., Bierma-Zeinstra, S., Runhaar, J., Sawitzke, A., McAlindon, T., Atchia, I., Lambert, R., Hashem Hasempur, M., Walsh, D., Doherty, M., & Zhang, W. (2019, May). Identifying predictors of placebo response in osteoarthritis clinical trials of three agents with different routes of delivery: a meta-analysis using individual patient data. Presented at 2019 World Congress on Osteoarthritis, Toronto, Canada

Self-report central mechanisms trait predicts knee pain persistence in the Knee Pain In the Community (KPIC) cohort (2019)
Presentation / Conference Contribution
McWilliams, D., Akin-Akinyosoye, K., Walsh, D., Frowd, N., Swaithes, L., Fernandes, G., Stocks, J., Sarmanova, A., Zhang, W., Doherty, M., Valdes, A., & Ferguson, E. (2019, April). Self-report central mechanisms trait predicts knee pain persistence in the Knee Pain In the Community (KPIC) cohort. Poster presented at Rheumatology 2019, Birmingham, UK

Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink (2019)
Journal Article
Nakafero, G., Grainge, M. J., Myles, P., Mallen, C. D., Zhang, W., Doherty, M., Nguyen-Van-Tam, J. S., & Abhishek, A. (2019). Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink. Annals of the Rheumatic Diseases, 78(8), 1122-1126. https://doi.org/10.1136/annrheumdis-2019-215086

Objectives To examine the association between inactivated influenza vaccine (IIV) administration and primary care consultation for joint pain, rheumatoid arthritis (RA) flare, corticosteroid prescription, vasculitis, and unexplained fever in people w... Read More about Association between inactivated influenza vaccine and primary care consultations for autoimmune rheumatic disease flares: a self-controlled case series study using data from the Clinical Practice Research Datalink.

Risk Factors for Knee Osteoarthritis in Retired Professional Footballers: A Cross-Sectional Study (2019)
Journal Article
Parekh, S. M., Fernandes, G. S., Moses, J. P., Fuller, C. W., Scammell, B. E., Batt, M. E., Zhang, W., & Doherty, M. (2021). Risk Factors for Knee Osteoarthritis in Retired Professional Footballers: A Cross-Sectional Study. Clinical Journal of Sport Medicine, 31(3), 281-288. https://doi.org/10.1097/JSM.0000000000000742

Objective: To determine risk factors for three knee osteoarthritis (KOA) outcomes, knee pain (KP), radiographic KOA (RKOA) and total knee replacement (TKR), in professional footballers.
Design: This was a cross-sectional study involving a postal que... Read More about Risk Factors for Knee Osteoarthritis in Retired Professional Footballers: A Cross-Sectional Study.