All Outputs (70)

Admission to hospital in the UK at a weekend does not influence the prognosis of adults with community-acquired pneumonia (2020)
Journal Article

Outcomes for adults with community-acquired pneumonia (CAP) admitted to hospital at the weekend were compared with those admitted during weekdays using data from the British Thoracic Society national CAP audits. Of 31?400 cases, 40.7% were weekend ad... Read More about Admission to hospital in the UK at a weekend does not influence the prognosis of adults with community-acquired pneumonia.

A retrospective database study of oral corticosteroid and bisphosphonate prescribing patterns in England (2020)
Journal Article

© 2020, The Author(s). Exposure to oral corticosteroids (OCS) is associated with an increased risk of osteoporosis and fragility fractures. Guidelines suggest bisphosphonate (BP) therapy as the first-line treatment of glucocorticoid-induced osteoporo... Read More about A retrospective database study of oral corticosteroid and bisphosphonate prescribing patterns in England.

A systematic review of survival following anti-cancer treatment for small cell lung cancer (2020)
Journal Article

Objectives: We conducted a systematic review and meta-analysis of survival following treatment recommended by the European Society of Medical Oncology for SCLC in order to determine a benchmark for novel therapies to be compared with. Materials and m... Read More about A systematic review of survival following anti-cancer treatment for small cell lung cancer.

Pneumococcal serotype trends, surveillance and risk factors in UK adult pneumonia, 2013 – 2018 (2019)
Journal Article

Background: Changes over the last five years (2013

Prevalence of tobacco use in healthcare workers: A systematic review and meta-analysis (2019)
Journal Article

© 2019 Nilan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cred... Read More about Prevalence of tobacco use in healthcare workers: A systematic review and meta-analysis.

Effect of tobacco smoking on the risk of developing community acquired pneumonia: A systematic review and meta-analysis (2019)
Journal Article

Aim To summarise and quantify the effect of tobacco smoking on the risk of developing community acquired pneumonia (CAP) in adults. Methods We systematically searched MEDLINE, Embase, CINAHL, PsychINFO and Web of Science, from inception to Octob... Read More about Effect of tobacco smoking on the risk of developing community acquired pneumonia: A systematic review and meta-analysis.

The Its Not JUST Idiopathic pulmonary fibrosis Study (INJUSTIS): Description of the protocol for a multicentre prospective observational cohort study identifying biomarkers of progressive fibrotic lung disease (2019)
Journal Article

Introduction: The Its Not JUST Idiopathic pulmonary fibrosis Study (INJUSTIS) is a multicentre, prospective, observational cohort study. The aims of this study are to identify genetic, serum and other biomarkers that may identify specific molecular m... Read More about The Its Not JUST Idiopathic pulmonary fibrosis Study (INJUSTIS): Description of the protocol for a multicentre prospective observational cohort study identifying biomarkers of progressive fibrotic lung disease.

Predicting fracture risk in patients with chronic obstructive pulmonary disease: a UK-based population-based cohort study (2019)
Journal Article

Patient reported distress can aid clinical decision making in idiopathic pulmonary fibrosis: analysis of the PROFILE cohort (2019)
Journal Article

Idiopathic pulmonary fibrosis is a progressive and fatal interstitial lung disease. We aimed to determine if patient response to a palliative assessment survey could predict disease progression or death. We undertook a cross-sectional study in a U... Read More about Patient reported distress can aid clinical decision making in idiopathic pulmonary fibrosis: analysis of the PROFILE cohort.

Patient reported outcome measures in the recovery of adults hospitalised with community-acquired pneumonia: a systematic review (2019)
Journal Article

Symptomatic and functional recovery are important patient-reported outcome measures (PROMs) in community-acquired pneumonia (CAP) that are increasingly used as trial endpoints. This systematic review summarises the literature on PROMs in CAP. Comp... Read More about Patient reported outcome measures in the recovery of adults hospitalised with community-acquired pneumonia: a systematic review.

Temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: FAST (2018)
Journal Article

Hip fracture outcomes in patients with COPD (2018)
Journal Article

Hip fractures are common in patients with COPD and contemporary outcome data is needed. Patients admitted with a hip fracture to one acute trust (2010-2015) were assessed prospectively (UK National Hip Fracture Database audit) and mortality data col... Read More about Hip fracture outcomes in patients with COPD.

Factors influencing treatment selection and thirty-day mortality following chemotherapy for people with small cell lung cancer: an analysis of national audit data (2018)
Journal Article

Background Thirty-day mortality after treatment for lung cancer is a measure of unsuccessful outcome and where treatment should have been avoided. Guidelines recommend offering chemotherapy to individuals with small cell lung cancer (SCLC) who ha... Read More about Factors influencing treatment selection and thirty-day mortality following chemotherapy for people with small cell lung cancer: an analysis of national audit data.

Investigating the discriminative value of Early Warning Scores in patients with respiratory disease using a retrospective cohort analysis of admissions to Nottingham University Hospitals Trust over a 2-year period (2018)
Journal Article

Objective: Early Warning Scores (EWSs) are used to monitor patients for signs of imminent deterioration. Although used in respiratory disease, EWSs have not been well studied in this population, despite the underlying cardiopulmonary pathophysiology... Read More about Investigating the discriminative value of Early Warning Scores in patients with respiratory disease using a retrospective cohort analysis of admissions to Nottingham University Hospitals Trust over a 2-year period.

Risk of fall in patients with COPD (2018)
Journal Article

A matched cohort study was conducted to determine the incidence of falls in patients following a diagnosis of COPD using a UK primary care database. 44 400 patients with COPD and 175?545 non-COPD subjects were identified. The incidence rate of fall p... Read More about Risk of fall in patients with COPD.

Quadrupling inhaled glucocorticoid dose to abort asthma exacerbations (2018)
Journal Article

Copyright © 2018 Massachusetts Medical Society. BACKGROUND Asthma exacerbations are frightening for patients and are occasionally fatal. We tested the concept that a plan for patients to manage their asthma (self-management plan), which included a te... Read More about Quadrupling inhaled glucocorticoid dose to abort asthma exacerbations.

A survey of tobacco dependence treatment guidelines content in 61 countries (2018)
Journal Article

Aims: To assess tobacco dependence treatment guidelines content in accordance with Article 14 of the World Health Organisation (WHO) Framework Convention on Tobacco Control (FCTC) and its guidelines, and association between content and country income... Read More about A survey of tobacco dependence treatment guidelines content in 61 countries.

Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics (2018)
Journal Article

Background Sepsis represents a significant public health burden, costing the NHS £2.5 billion annually, with 35% mortality in 2006. The aim of this exploratory study was to investigate risk factors predictive of 30-day mortality amongst patients w... Read More about Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics.

13-Valent vaccine serotype pneumococcal community acquired pneumonia in adults in high clinical risk groups (2018)
Journal Article

There is debate regarding the value of vaccinating adults with the 13-valent pneumococcal conjugate vaccine (PCV-13). This analysis was conducted to investigate the risk of PCV-13 serotype community acquired pneumonia (CAP) in hospitalised adults wit... Read More about 13-Valent vaccine serotype pneumococcal community acquired pneumonia in adults in high clinical risk groups.

The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database (2017)
Journal Article

Pulmonary rehabilitation is recommended for patients with COPD to improve physical function, breathlessness and quality of life. Using The Health Information Network (THIN) primary care database in UK, we compared the demographic and clinical paramet... Read More about The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database.