Skip to main content

Research Repository

Advanced Search

All Outputs (5)

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study (2018)
Journal Article
Shrine, N., Portelli, M. A., John, C., Soler Artigas, M., Bennett, N., Hall, R., …Sayers, I. (2019). Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. Lancet Respiratory Medicine, 7(1), 20-34. https://doi.org/10.1016/S2213-2600%2818%2930389-8

Background Few genetic studies that focus on moderate-to-severe asthma exist. We aimed to identity novel genetic variants associated with moderate-to-severe asthma, see whether previously identified genetic variants for all types of asthma contribut... Read More about Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics (2018)
Journal Article
Sanderson, M., Chikhani, M., Blyth, E., Wood, S., Moppett, I. K., McKeever, T., & Simmonds, M. J. (2018). Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics. Journal of the Intensive Care Society, 19(4), 299-304. https://doi.org/10.1177/1751143718758975

Background Sepsis represents a significant public health burden, costing the NHS £2.5 billion annually, with 35% mortality in 2006. The aim of this exploratory study was to investigate risk factors predictive of 30-day mortality amongst patients w... Read More about Predicting 30-day mortality in patients with sepsis: an exploratory analysis of process of care and patient characteristics.

Lung cancer diagnosed following an emergency admission: Mixed methods study of the management, outcomes and needs and experiences of patients and carers (2016)
Journal Article
Wilcock, A., Crosby, V., Hussain, A., McKeever, T. M., Manderson, C., Farnan, S., …Seymour, J. (2016). Lung cancer diagnosed following an emergency admission: Mixed methods study of the management, outcomes and needs and experiences of patients and carers. Respiratory Medicine, 114, 38-45. https://doi.org/10.1016/j.rmed.2016.03.006

Background In the UK, although 40% of patients with lung cancer are diagnosed following an emergency admission (EA), data is limited on their needs and experiences as they progress through diagnostic and treatment pathways. Methods Prospective... Read More about Lung cancer diagnosed following an emergency admission: Mixed methods study of the management, outcomes and needs and experiences of patients and carers.

The utility of exhaled nitric oxide in patients with suspected asthma (2016)
Journal Article
Martin, M., Wilson, E., Gerrard-Tarpey, W., Meakin, G., Hearson, G., McKeever, T., …Harrison, T. (2016). The utility of exhaled nitric oxide in patients with suspected asthma. Thorax, 71(6), https://doi.org/10.1136/thoraxjnl-2015-208014

The value of FENO measurements in patients with symptoms suggestive of asthma is unclear. We performed an observational study to assess the ability of FENO to diagnose asthma and to predict response to inhaled corticosteroids (ICS). Our findings sugg... Read More about The utility of exhaled nitric oxide in patients with suspected asthma.