Asymmetric pentafulvene carbometalation-access to enantiopure titanocene dichlorides of biological relevance

Cini, Melchior; Bradshaw, Tracey D.; Woodward, Simon; Lewis, William

doi:10.1002/anie.201508034

All Outputs (2)

An Apoferritin-based Drug Delivery System for the Tyrosine Kinase Inhibitor Gefitinib (2015)
Journal Article
Kuruppu, A. I., Zhang, L., Collins, H. M., Turyanska, L., Thomas, N. R., & Bradshaw, T. D. (2015). An Apoferritin-based Drug Delivery System for the Tyrosine Kinase Inhibitor Gefitinib. Advanced Healthcare Materials, 4(18), 2816-2821. https://doi.org/10.1002/adhm.201500389

Asymmetric pentafulvene carbometalation-access to enantiopure titanocene dichlorides of biological relevance (2015)
Journal Article
Cini, M., Bradshaw, T. D., Woodward, S., & Lewis, W. (2015). Asymmetric pentafulvene carbometalation-access to enantiopure titanocene dichlorides of biological relevance. Angewandte Chemie International Edition, 54(47), https://doi.org/10.1002/anie.201508034

Unprecedented asymmetric copper-catalyzed addition of ZnEt2 (ZnBu2) to the exocyclic C[DOUBLE BOND]C bond of pentafulvenes C5H4([DOUBLE BOND]CHAr) (Ar=2-MeOPh and related species) results in enantiomerically enriched (up to 93:7 e.r.) cyclopentadieny... Read More about Asymmetric pentafulvene carbometalation-access to enantiopure titanocene dichlorides of biological relevance.