Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial.

John, Michelle; Cockcroft, John R.; McKeever, Tricia M.; Coward, William R.; Shale, Dennis J.; Johnson, Simon R.; Thornton, Jim; Harrison, Timothy W.; Knox, Alan J.; Bolton, Charlotte E.

doi:10.2147/COPD.S76061

All Outputs (3)

Using venous blood gas analysis in the assessment of COPD exacerbations: a prospective cohort study (2015)
Journal Article

Introduction: Identifying acute hypercapnic respiratory failure is crucial in the initial management of acute exacerbations of COPD. Guidelines recommend obtaining arterial blood samples but these are more difficult to obtain than venous. We assessed... Read More about Using venous blood gas analysis in the assessment of COPD exacerbations: a prospective cohort study.

A randomised controlled trial of small particle inhaled steroids in refractory eosinophilic asthma (SPIRA) (2015)
Journal Article

Background: Some patients with refractory asthma have evidence of uncontrolled eosinophilic inflammation in the distal airways. While traditional formulations of inhaled steroids settle predominantly in the large airways, newer formulations with an e... Read More about A randomised controlled trial of small particle inhaled steroids in refractory eosinophilic asthma (SPIRA).

Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial. (2015)
Journal Article

BACKGROUND: There is excess cardiovascular mortality in patients with chronic obstructive pulmonary disease. Aortic stiffness, an independent predictor of cardiovascular risk, and systemic and airway inflammation are increased in patients with the... Read More about Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial..