Genetic variants in glutamate-, A??, and tau-related pathways determine polygenic risk for Alzheimer's disease
(2020)
Journal Article
© 2020 Elsevier Inc. Synapse loss is an early event in late-onset Alzheimer's disease (LOAD). In this study, we have assessed the capacity of a polygenic risk score (PRS) restricted to synapse-encoding loci to predict LOAD. We used summary statistics... Read More about Genetic variants in glutamate-, A??, and tau-related pathways determine polygenic risk for Alzheimer's disease.