All Outputs (77)

Physical model tests and numerical simulation for assessing the stability of brick-lined tunnels (2016)
Journal Article

Nowadays, numerical modelling is increasingly used to assess the stability of tunnels and underground caverns. However, an analysis of the mechanical behaviour of existing brick-lined tunnels remains challenging due to the complex material component... Read More about Physical model tests and numerical simulation for assessing the stability of brick-lined tunnels.

Calpain-1 is associated with adverse relapse free survival in breast cancer: a confirmatory study (2016)
Journal Article

Standardization efforts: the relationship between knowledge dimensions, search processes and innovation outcomes (2015)
Journal Article

We explore how a standardization effort (i.e., when a firm pursues standards to further innovation) involves different search processes for knowledge and innovation outcomes. Using an inductive case study of Vanke, a leading Chinese property develope... Read More about Standardization efforts: the relationship between knowledge dimensions, search processes and innovation outcomes.

Strategic and natural risk in entrepreneurship: an experimental study (2015)
Journal Article

We report on the results of experiments where participants choose between entrepreneurship and an outside option. Entrepreneurs enter a market and then make investment decisions to capture value. Payoffs depend on both strategic risk (i.e. the invest... Read More about Strategic and natural risk in entrepreneurship: an experimental study.

Multiple pathways regulate Cten in colorectal cancer without a Tensin switch. (2015)
Journal Article

Conflict minerals and supply chain due diligence: an exploratory study of multi-tier supply chains (2015)
Journal Article

As recently stakeholders complain about the use of conflict minerals in consumer products that are often invisible to them in final products, firms across industries implement conflict mineral management practices. Conflict minerals are those, whose... Read More about Conflict minerals and supply chain due diligence: an exploratory study of multi-tier supply chains.

Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer (2015)
Journal Article

Radiation?induced DNA damage activates the DNA damage response (DDR). DDR up?regulation may predict radio?resistance and increase the risk of early local recurrence despite radiotherapy in early stage breast cancers. In 1755 early stage breast cancer... Read More about Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer.

Combining ‘‘real effort’’ with induced effort costs: the ball-catching task (2015)
Journal Article

We introduce the “ball-catching task”, a novel computerized task, which combines a tangible action (“catching balls”) with induced material cost of effort. The central feature of the ball-catching task is that it allows researchers to manipulate the... Read More about Combining ‘‘real effort’’ with induced effort costs: the ball-catching task.

Calpain in Breast Cancer: Role in Disease Progression and Treatment Response (2015)
Journal Article

Risk taking and information aggregation in groups (2015)
Journal Article

We report a controlled laboratory experiment examining risk-taking and information aggregation in groups facing a common risk. The experiment allows us to examine how subjects respond to new information, in the form of both privately observed signals... Read More about Risk taking and information aggregation in groups.

Lymphovascular invasion assessment and prognostic impact in melanoma and breast cancer (2015)
Journal Article

© 2015, Histology and Histopathology. All rights reserved. The presence of lymphovascular invasion is a recognised poor prognostic factor in a wide range of tumour types. Vascular invasion was historically identified through haematoxylin and eosin st... Read More about Lymphovascular invasion assessment and prognostic impact in melanoma and breast cancer.

Discretionary sanctions and rewards in the repeated inspection game (2015)
Journal Article

We experimentally investigate a repeated “inspection game” where, in the stage game, an employee can either work or shirk and an employer simultaneously chooses to inspect or not inspect. The unique equilibrium of the stage game is in mixed strategie... Read More about Discretionary sanctions and rewards in the repeated inspection game.

Quality assessment of an Ultra-Wide Band positioning system for indoor wheelchair court sports (2015)
Journal Article

Ultra-Wide Band radio positioning systems are maturing very quickly and now represent a good candidate for indoor positioning. The aim of this study was to undertake a quality assessment on the use of a commercial Ultra-Wide Band positioning system f... Read More about Quality assessment of an Ultra-Wide Band positioning system for indoor wheelchair court sports.

FKBPL: a marker of good prognosis in breast cancer (2015)
Journal Article

FK506-binding protein-like (FKBPL) has established roles as an anti-tumor protein, with a therapeutic peptide based on this protein, ALM201, shortly entering phase I/II clinical trials. Here, we evaluated FKBPL’s prognostic ability in primary breast... Read More about FKBPL: a marker of good prognosis in breast cancer.

Structural aspects of MOF-based energy materials research at Diamond (2015)
Journal Article

Large-scale central facilities such as Diamond Light Source fulfil an increasingly pivotal role in many large-scale scientific research programmes. We illustrate these developments by reference to energy-centred projects at the University of Nottingh... Read More about Structural aspects of MOF-based energy materials research at Diamond.

Supramolecular binding and separation of hydrocarbons within a functionalised porous metal-organic framework (2015)
Journal Article

Supramolecular interactions are fundamental to host-guest binding in chemical and biological processes. Direct visualisation of such supramolecular interactions within host-guest systems is extremely challenging but crucial for the understanding of t... Read More about Supramolecular binding and separation of hydrocarbons within a functionalised porous metal-organic framework.

Low calpain-9 is associated with adverse disease-specific survival following endocrine therapy in breast cancer (2014)
Journal Article

Background The calpains are intracellular cysteine proteases that function in a variety of important cellular functions, including signalling, motility, apoptosis and survival. In breast cancer high calpain-1 and calpain-2 expression has been asso... Read More about Low calpain-9 is associated with adverse disease-specific survival following endocrine therapy in breast cancer.

Prognostic significance of lymphatic invasion in lymph node-positive breast carcinoma: findings from a large case series with long-term follow-up using immunohistochemical endothelial marker (2014)
Journal Article

Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapy (2014)
Journal Article

Metformin is under evaluation as a potential anticancer agent. Expression of total and phospho(Thr172)-adenosine monophosphate-activated kinase-α (AMPKα and pAMPKα(Thr172) respectively), a main metformin target, was examined in radiotherapy treated b... Read More about Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapy.

The clinicopathological and gene expression patterns associated with ulceration of primary melanoma (2014)
Journal Article