Nose-to-brain delivery: investigation of the rransport of nanoparticles with different surface characteristics and sizes in excised porcine olfactory epithelium

Mistry, Alpesh; Stolnik, Snjezana; Illum, Lisbeth

doi:10.1021/acs.molpharmaceut.5b00088

All Outputs (3)

Live imaging of cellular internalization of single colloidal particle by combined label-free and fluorescence total internal reflection microscopy (2015)
Journal Article

In this work we utilize the combination of label-free total internal reflection microscopy and total internal reflectance fluorescence (TIRM/TIRF) microscopy to achieve a simultaneous, live imaging of single, label-free colloidal particle endocytosis... Read More about Live imaging of cellular internalization of single colloidal particle by combined label-free and fluorescence total internal reflection microscopy.

Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA (2015)
Journal Article

Helicobacter pylori is a leading cause of peptic ulceration and gastric cancer worldwide. To achieve colonization of the stomach, this Gram-negative bacterium adheres to Lewis(b) (Le(b)) antigens in the gastric mucosa using its outer membrane protein... Read More about Structural basis of Lewis(b) antigen binding by the Helicobacter pylori adhesin BabA.

Nose-to-brain delivery: investigation of the rransport of nanoparticles with different surface characteristics and sizes in excised porcine olfactory epithelium (2015)
Journal Article

The ability to deliver therapeutically relevant amounts of drugs directly from the nasal cavity to the central nervous system to treat neurological diseases is dependent on the availability of efficient drug delivery systems. Increased delivery and/o... Read More about Nose-to-brain delivery: investigation of the rransport of nanoparticles with different surface characteristics and sizes in excised porcine olfactory epithelium.