All Outputs (2)

The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge (2014)
Journal Article
Bannunah, A. M., Vllasaliu, D., Lord, J., & Stolnik, . S. (2014). The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge. Molecular Pharmaceutics, 11(12), 4363-4373. doi:10.1021/mp500439c

This study investigated the effect of nanoparticle size (50 and 100 nm) and surface charge on their interaction with Caco-2 monolayers as a model of the intestinal epithelium, including cell internalization pathways and the level of transepithelial t... Read More about The mechanisms of nanoparticle internalization and transport across an intestinal epithelial cell model: effect of size and surface charge.

Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules (2014)
Journal Article
Stolnik-Trenkic, S., Vllasaliua, D., Falcone, F. H., & Garnett, M. (2014). Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules. Experimental Cell Research, 323(1), 218-231. https://doi.org/10.1016/j.yexcr.2014.02.022

This work examines the potential drug delivery barrier of the basement membrane (BM) by assessing the permeability of select macromolecules and nanoparticles. The study further extends to probing the effect of BM on intestinal epithelial cell attachm... Read More about Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules.