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All Outputs (3)

T(2)-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS (2014)
Journal Article
Evans, M. C., Serres, . S., Khrapitchev, A. A., Stolp, H. B., Anthony, D. C., Talbot, K., …Sibson, N. R. (2014). T(2)-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS. Journal of Cerebral Blood Flow and Metabolism, 34(5), 785-793. https://doi.org/10.1038/jcbfm.2014.19

Neuroinflammation has been identified as a potential therapeutic target in amyotrophic lateral sclerosis (ALS), but relevant biomarkers are needed. The superoxide dismutase (SOD1)G93A transgenic mouse model of ALS offers a unique opportunity to study... Read More about T(2)-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS.

Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker (2014)
Journal Article
ER, O., Serres, S., V, K., M, T., B, C., MS, S., …NR., S. (2014). Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker. Journal of Nuclear Medicine, 55(2), 275-280. https://doi.org/10.2967/jnumed.113.127449

Metastatic spread of cancer cells to the brain is associated with high mortality, primarily because current diagnostic tools identify only well-advanced metastases. Brain metastases have been shown to induce a robust glial response, including both as... Read More about Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker.