STAT3-mediated astrocyte reactivity associated with brain metastasis contributes to neurovascular dysfunction
(2020)
Journal Article
Sarmiento Soto, M., Larkin, J. R., Martin, C., Khrapitchev, A. A., Maczka, M., Economopoulos, V., …Sibson, N. R. (2020). STAT3-mediated astrocyte reactivity associated with brain metastasis contributes to neurovascular dysfunction. Cancer Research, 80(24), 5642-5655. https://doi.org/10.1158/0008-5472.CAN-20-2251
© 2020 American Association for Cancer Research. Astrocytes are thought to play a pivotal role in coupling neural activity and cerebral blood flow. However, it has been shown that astrocytes undergo morphologic changes in response to brain metastasis... Read More about STAT3-mediated astrocyte reactivity associated with brain metastasis contributes to neurovascular dysfunction.