Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth
(2006)
Journal Article
Telomerase catalytic subunit (TERT) seems a key factor controlling telomerase activity, telomere length, and cell growth. To further address this issue, we forced expression of a catalytically inactive mutant human TERT (hTERT) in hTERT-immortalised... Read More about Telomerase with mutated catalytic motifs has dominant negative effects on telomerase activity and inhibits cell growth.