All Outputs (3)

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice (2016)
Journal Article
Poissonnier, A., Sanséau, D., Le Gallo, M., Malleter, M., Levoin, N., Viel, R., …Legembre, P. (2016). CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. Immunity, 45(1), 209-223. https://doi.org/10.1016/j.immuni.2016.06.028

CD95 ligand (CD95L) is expressed by immune cells and triggers apoptotic death. Metalloprotease-cleaved CD95L (cl-CD95L) is released into the bloodstream but does not trigger apoptotic signaling. Hence, the pathophysiological role of cl-CD95L remains... Read More about CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.

TGF-? superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development (2015)
Journal Article
Japa, O., Hodgkinson, J. E., Emes, R. D., & Flynn, R. J. (2015). TGF-? superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development. Veterinary Research, 46(1), Article 29. https://doi.org/10.1186/s13567-015-0167-2

© 2015 Japa et al.; licensee BioMed Central. The helminth Fasciola hepatica causes fasciolosis throughout the world, a major disease of livestock and an emerging zoonotic disease in humans. Sustainable control mechanisms such as vaccination are urgen... Read More about TGF-? superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development.

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis (2013)
Journal Article
Hams, E., Armstrong, M. E., Barlow, J. L., Saunders, S. P., Schwartz, C., Cooke, G., …Fallon, P. G. (2014). IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis. Proceedings of the National Academy of Sciences, 111(1), 367-372. https://doi.org/10.1073/pnas.1315854111

Disease conditions associated with pulmonary fibrosis are progressive and have a poor long-term prognosis with irreversible changes in airway architecture leading to marked morbidity and mortalities. Using murine models we demonstrate a role for inte... Read More about IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.