The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite

Shang, V.C.M.; O'Sullivan, Saoirse; Kendall, D.A.; Roberts, Richard E.

doi:10.1016/j.phrs.2016.01.023

All Outputs (3)

?9-tetrahydrocannabinol reverses TNF?-induced increase in airway epithelial cell permeability through CB2 receptors (2016)
Journal Article

Despite pharmacological treatment, bronchial hyperresponsiveness continues to deteriorate as airway remodelling persists in airway inflammation. Previous studies have demonstrated that the phytocannabinoid ?9-tetrahydrocannabinol (THC)reverses bronch... Read More about ?9-tetrahydrocannabinol reverses TNF?-induced increase in airway epithelial cell permeability through CB2 receptors.

Effect of simvastatin on vascular tone in porcine coronary artery: potential role of the mitochondria (2016)
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Statins induce acute vasorelaxation which may contribute to the overall benefits of statins in the treatment of cardiovascular disease. The mechanism underlying this relaxation is unknown. As statins have been shown to alter mitochondrial function, i... Read More about Effect of simvastatin on vascular tone in porcine coronary artery: potential role of the mitochondria.

The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite (2016)
Journal Article

Injury to the bronchial epithelium in respiratory diseases such as asthma and COPD results in the lossof barrier function and an elevated sensitivity to environmental insults. An increased release of theendogenous cannabinoid, anandamide in response... Read More about The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite.