All Outputs (59)

Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography (2024)
Journal Article
Rier, L., Rhodes, N., Pakenham, D. O., Boto, E., Holmes, N., Hill, R. M., …Brookes, M. J. (2024). Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography. eLife, 13, Article RP94561. https://doi.org/10.7554/elife.94561.3

Neural oscillations mediate the coordination of activity within and between brain networks, supporting cognition and behaviour. How these processes develop throughout childhood is not only an important neuroscientific question but could also shed lig... Read More about Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography.

The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study (2024)
Journal Article
Rier, L., Rhodes, N., Pakenham, D., Boto, E., Holmes, N., Hill, R. M., …Brookes, M. J. (2024). The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study. eLife, Article 94561v1. https://doi.org/10.7554/eLife.94561.1

Neural oscillations mediate coordination of activity within and between brain networks, supporting cognition and behaviour. How these processes develop throughout childhood is not only a critical neuroscientific question but could also shed light on... Read More about The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study.

Test-retest reliability of the human connectome: An OPM-MEG study (2023)
Journal Article
Rier, L., Michelmann, S., Ritz, H., Shah, V., Hill, R. M., Osborne, J., …Boto, E. (2023). Test-retest reliability of the human connectome: An OPM-MEG study. Imaging Neuroscience, 1, 1-20. https://doi.org/10.1162/imag_a_00020

Magnetoencephalography with optically pumped magnetometers (OPM-MEG) offers a new way to record electrophysiological brain function, with significant advantages over conventional MEG, including adaptability to head shape/size, free movement during sc... Read More about Test-retest reliability of the human connectome: An OPM-MEG study.

The impact of variations in subject geometry, respiration and coil repositioning on the specific absorption rate in parallel transmit abdominal imaging at 7 T (2023)
Journal Article
Doran, E., Naim, I., Bowtell, R., Gowland, P. A., Glover, P. M., & Bawden, S. (in press). The impact of variations in subject geometry, respiration and coil repositioning on the specific absorption rate in parallel transmit abdominal imaging at 7 T. NMR in Biomedicine, Article e5032. https://doi.org/10.1002/nbm.5032

Parallel transmit MRI at 7 T has increasingly been adopted in research projects and provides increased signal‐to‐noise ratios and novel contrasts. However, the interactions of fields in the body need to be carefully considered to ensure safe scanning... Read More about The impact of variations in subject geometry, respiration and coil repositioning on the specific absorption rate in parallel transmit abdominal imaging at 7 T.

An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts (2023)
Journal Article
Holmes, N., Bowtell, R., Brookes, M. J., & Taulu, S. (2023). An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts. Sensors, 23(14), Article 6537. https://doi.org/10.3390/s23146537

The signal space separation (SSS) method is routinely employed in the analysis of multichannel magnetic field recordings (such as magnetoencephalography (MEG) data). In the SSS method, signal vectors are posed as a multipole expansion of the magnetic... Read More about An Iterative Implementation of the Signal Space Separation Method for Magnetoencephalography Systems with Low Channel Counts.

Naturalistic Hyperscanning with Wearable Magnetoencephalography (2023)
Journal Article
Holmes, N., Rea, M., Hill, R. M., Boto, E., Leggett, J., Edwards, L. J., …Bowtell, R. (2023). Naturalistic Hyperscanning with Wearable Magnetoencephalography. Sensors, 23(12), Article 5454. https://doi.org/10.3390/s23125454

The evolution of human cognitive function is reliant on complex social interactions which form the behavioural foundation of who we are. These social capacities are subject to dramatic change in disease and injury; yet their supporting neural substra... Read More about Naturalistic Hyperscanning with Wearable Magnetoencephalography.

Non-invasive measurements of ictal and interictal epileptiform activity using optically pumped magnetometers (2023)
Journal Article
Hillebrand, A., Holmes, N., Sijsma, N., O’Neill, G. C., Tierney, T. M., Liberton, N., …Barnes, G. R. (2023). Non-invasive measurements of ictal and interictal epileptiform activity using optically pumped magnetometers. Scientific Reports, 13(1), Article 4623. https://doi.org/10.1038/s41598-023-31111-y

Magneto- and electroencephalography (MEG/EEG) are important techniques for the diagnosis and pre-surgical evaluation of epilepsy. Yet, in current cryogen-based MEG systems the sensors are offset from the scalp, which limits the signal-to-noise ratio... Read More about Non-invasive measurements of ictal and interictal epileptiform activity using optically pumped magnetometers.

Measurement of Frontal Midline Theta Oscillations using OPM-MEG (2023)
Journal Article
Rhodes, N., Rea, M., Boto, E., Rier, L., Shah, V., Hill, R. M., …Brookes, M. J. (2023). Measurement of Frontal Midline Theta Oscillations using OPM-MEG. NeuroImage, 271, Article 120024. https://doi.org/10.1016/j.neuroimage.2023.120024

Optically pumped magnetometers (OPMs) are an emerging lightweight and compact sensor that can measure magnetic fields generated by the human brain. OPMs enable construction of wearable magnetoencephalography (MEG) systems, which offer advantages over... Read More about Measurement of Frontal Midline Theta Oscillations using OPM-MEG.

Deuterium brain imaging at 7T during D2O dosing (2022)
Journal Article
Cocking, D., Damion, R. A., Franks, H., Jaconelli, M., Wilkinson, D., Brook, M., …Bowtell, R. (2023). Deuterium brain imaging at 7T during D2O dosing. Magnetic Resonance in Medicine, 89(4), 1514-1521. https://doi.org/10.1002/mrm.29539

Purpose To characterize the (2H) deuterium MR signal measured from human brain at 7T in participants loading with D2O to ˜1.5% enrichment over a six-week period. Methods 2H spectroscopy and imaging measurements were used to track the time-course... Read More about Deuterium brain imaging at 7T during D2O dosing.

Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity (2022)
Journal Article
Zhang, J., Najeeb, F., Wang, X., Xu, P., Omer, H., Zheng, J., …Wang, C. (2022). Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity. IEEE Access, 10, 121193-121203. https://doi.org/10.1109/access.2022.3222313

This work presents a free-breathing dynamic contrast-enhanced (DCE) MRI reconstruction method called low-rank plus sparse (L+S) with joint sparsity. The proposed method improved dynamic contrast performance by integrating an additional temporal Fast... Read More about Improved Dynamic Contrast-Enhanced MRI Using Low Rank with Joint Sparsity.

Chronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer's Association Global Consortium (2022)
Journal Article
de Erausquin, G. A., Snyder, H., Brugha, T. S., Seshadri, S., Carrillo, M., Sagar, R., …Vahidy, F. S. (2022). Chronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer's Association Global Consortium. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 8(1), Article e12348. https://doi.org/10.1002/trc2.12348

Introduction: Coronavirus disease 2019 (COVID-19) has caused >3.5 million deaths worldwide and affected >160 million people. At least twice as many have been infected but remained asymptomatic or minimally symptomatic. COVID-19 includes central nervo... Read More about Chronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer's Association Global Consortium.

Turning OPM-MEG into a Wearable Technology (2022)
Book Chapter
Rhodes, N., Holmes, N., Hill, R., Barnes, G., Bowtell, R., Brookes, M., & Boto, E. (2022). Turning OPM-MEG into a Wearable Technology. In E. Labyt, T. Sander, & R. Wakai (Eds.), Flexible High Performance Magnetic Field Sensors: On-Scalp Magnetoencephalography and Other Applications (195-223). Springer International Publishing. https://doi.org/10.1007/978-3-031-05363-4_11

This chapter explores the use of optically pumped magnetometers (OPMs) as a tool for magnetoencephalography (MEG). Conventional MEG systems use superconducting quantum interference devices (SQUIDs) to measure the femto-Tesla-level magnetic fields at... Read More about Turning OPM-MEG into a Wearable Technology.

A lightweight magnetically shielded room with active shielding (2022)
Journal Article
Holmes, N., Rea, M., Chalmers, J., Leggett, J., Edwards, L. J., Nell, P., …Bowtell, R. (2022). A lightweight magnetically shielded room with active shielding. Scientific Reports, 12, Article 13561. https://doi.org/10.1038/s41598-022-17346-1

Magnetically shielded rooms (MSRs) use multiple layers of materials such as MuMetal to screen external magnetic fields that would otherwise interfere with high precision magnetic field measurements such as magnetoencephalography (MEG). Optically pump... Read More about A lightweight magnetically shielded room with active shielding.

A global survey of healthcare professionals undertaking MRI of patients with cochlear implants: a heterogeneity of practice and opinions (2022)
Journal Article
Dewey, R. S., Bowtell, R., & Kitterick, P. (2022). A global survey of healthcare professionals undertaking MRI of patients with cochlear implants: a heterogeneity of practice and opinions. British Journal of Radiology, 95(1137), Article 20220213. https://doi.org/10.1259/bjr.20220213

Objective: To capture practice and opinions around the current clinical use of MRI in patients with cochlear implants (CIs), and to characterise patient progression from referral to image reporting. Methods: An online survey recruited 237 healthcare... Read More about A global survey of healthcare professionals undertaking MRI of patients with cochlear implants: a heterogeneity of practice and opinions.

Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging (2022)
Journal Article
Wang, C., Martins-Bach, A. B., Alfaro-Almagro, F., Douaud, G., Klein, J. C., Llera, A., …Miller, K. L. (2022). Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging. Nature Neuroscience, 25(6), 818-831. https://doi.org/10.1038/s41593-022-01074-w

A key aim in epidemiological neuroscience is identification of markers to assess brain health and monitor therapeutic interventions. Quantitative susceptibility mapping (QSM) is an emerging magnetic resonance imaging technique that measures tissue ma... Read More about Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging.

Using OPM-MEG in contrasting magnetic environments (2022)
Journal Article
Hill, R. M., Devasagayam, J., Holmes, N., Boto, E., Shah, V., Osborne, J., …Brookes, M. J. (2022). Using OPM-MEG in contrasting magnetic environments. NeuroImage, 253, Article 119084. https://doi.org/10.1016/j.neuroimage.2022.119084

Magnetoencephalography (MEG) has been revolutionised by optically pumped magnetometers (OPMs). “OPM-MEG” offers higher sensitivity, better spatial resolution, and lower cost than conventional instrumentation based on superconducting quantum interfere... Read More about Using OPM-MEG in contrasting magnetic environments.

Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children (2022)
Journal Article
Boto, E., Shah, V., Hill, R. M., Rhodes, N., Osborne, J., Doyle, C., …Brookes, M. J. (2022). Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children. NeuroImage, 252, Article 119027. https://doi.org/10.1016/j.neuroimage.2022.119027

Optically-pumped magnetometers (OPMs) are an established alternative to superconducting sensors for magnetoencephalography (MEG), offering significant advantages including flexibility to accommodate any head size, uniform coverage, free movement duri... Read More about Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children.

Practical real-time MEG-based neural interfacing with optically pumped magnetometers (2021)
Journal Article
Wittevrongel, B., Holmes, N., Boto, E., Hill, R., Rea, M., Libert, A., …Brookes, M. J. (2021). Practical real-time MEG-based neural interfacing with optically pumped magnetometers. BMC Biology, 19(1), Article 158. https://doi.org/10.1186/s12915-021-01073-6

Background: Brain-computer interfaces decode intentions directly from the human brain with the aim to restore lost functionality, control external devices or augment daily experiences. To combine optimal performance with wide applicability, high-qual... Read More about Practical real-time MEG-based neural interfacing with optically pumped magnetometers.

Magnetic Field Mapping and Correction for Moving OP-MEG (2021)
Journal Article
Mellor, S., Tierney, T. M., O'Neill, G. C., Alexander, N., Seymour, R. A., Holmes, N., …Barnes, G. R. (2022). Magnetic Field Mapping and Correction for Moving OP-MEG. IEEE Transactions on Biomedical Engineering, 69(2), 528-536. https://doi.org/10.1109/TBME.2021.3100770

Background: Optically pumped magnetometers (OPMs) have made moving, wearable magnetoencephalography (MEG) possible. The OPMs typically used for MEG require a low background magnetic field to operate, which is achieved using both passive and active ma... Read More about Magnetic Field Mapping and Correction for Moving OP-MEG.

Precision magnetic field modelling and control for wearable magnetoencephalography (2021)
Journal Article
Rea, M., Holmes, N., Hill, R. M., Boto, E., Leggett, J., Edwards, L. J., …Brookes, M. J. (2021). Precision magnetic field modelling and control for wearable magnetoencephalography. NeuroImage, 241, Article 118401. https://doi.org/10.1016/j.neuroimage.2021.118401

Optically-pumped magnetometers (OPMs) are highly sensitive, compact magnetic field sensors, which offer a viable alternative to cryogenic sensors (superconducting quantum interference devices – SQUIDs) for magnetoencephalography (MEG). With the promi... Read More about Precision magnetic field modelling and control for wearable magnetoencephalography.