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The influence of bioreactor geometry and the mechanical environment on engineered tissues (2010)
Journal Article
Osborne, J., O'Dea, R. D., Whiteley, J., Byrne, H., & Waters, S. (2010). The influence of bioreactor geometry and the mechanical environment on engineered tissues. Journal of Biomechanical Engineering, 132(5), Article 051006. https://doi.org/10.1115/1.4001160

A three phase model for the growth of a tissue construct within a perfusion bioreactor is examined. The cell population (and attendant extracellular matrix), culture medium and porous scaffold are treated as distinct phases. The bioreactor system is... Read More about The influence of bioreactor geometry and the mechanical environment on engineered tissues.

A multiphase model for tissue construct growth in a perfusion bioreactor (2010)
Journal Article
O'Dea, R. D., Waters, S. L., & Byrne, H. M. (2010). A multiphase model for tissue construct growth in a perfusion bioreactor. Mathematical Medicine and Biology, 27(2), https://doi.org/10.1093/imammb/dqp003

The growth of a cell population within a rigid porous scaffold in a perfusion bioreactor is studied, using a three phase continuum model of the type presented by Lemon et al. (2006, Multiphase modelling of tissue growth using the theory of mixtures.... Read More about A multiphase model for tissue construct growth in a perfusion bioreactor.